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Typhoid confirmed in Mozambique (and Malawi)

alert

Senior Moderator
I can't even imagine the cause on this one.

http://www.promedmail.org/pls/otn/f..._BACK_PAGE,F2400_P1001_PUB_MAIL_ID:1000,78306

UNDIAGNOSED FATALITIES - MALAWI, MOZAMBIQUE: REQUEST FOR INFORMATION
********************************************************************
A ProMED-mail post
<http://www.promedmail.org>
ProMED-mail is a program of the
International Society for Infectious Diseases
<http://www.isid.org>

Date: 11 Jul 2009
Source: Nation Online, Window on Malawi [edited]
<http://www.nationmw.net/newsdetail.asp?article_id=3384>


Strange disease hits Neno
-------------------------
An unknown disease has killed 15 people out of 103 patients since May
this year [2009] in 2 bordering villages of Mtemankhawa and Datson in
Malawi and Mozambique, respectively. Mtemankhawa Village, with a
total population of 753, is in the area of TA Dambe in Neno while
Datson Village, in the area of Chief Tsangano in Mozambique, has a
population of 329.

Traditional leaders in the area and Secretary for Health Chris
Kang'ombe have confirmed the occurrence of the unknown disease and
the deaths. "It is true that 15 people out of 103 cases have died so
far. 8 are from the Malawi side while 7 from Mozambique side. 5 are
admitted to Neno District Hospital," said Kang'ombe in an interview
yesterday. He described the disease as "not well known".

The PS said the ministry has already sent laboratory samples to South
Africa for analysis. The symptoms of the disease, according to
Kang'ombe, include stiff neck, dehydration, fever, headache, joint
pain, discomfort in abdomen and loss of voice. He ruled out meningitis.

While waiting for the results of the samples, he said, the ministry
is treating some patients with antibiotics and has supplied the
people with Chlorine because "they use unprotected wells for water."
He said the area is "very cold" and some people are forced not to
bathe for many days. He said some live together with animals in their
round grass-thatched houses which have no windows. "These could be
some contributing factors but it is yet to be seen," said Kang'ombe.
He said the ministry has also set up a treatment camp in the area to
handle minor cases.

Group Village Headman Chakulembera, who oversees Mtemankhawa Village,
said in an interview on Wednesday [8 Jul 2009] in Mwanza that those
affected by the disease develop stiff jaws, neck and have abdominal
pains. "It makes it difficult for them to eat," he said.
Chakulembera, who was flanked by village headman Mtemankhawa and T/A
Dambe's envoy MacDonald Chindimwe, said among those killed include 5
pupils, 3 from Chawe Primary School.

"On average, we have 3 or 4 deaths per week. People are worried about
the development because they cannot work in their wheat and Irish
potato gardens," said Chakulembera, who was supported by Mtemankhawa
who said: "The latest death was on Monday this week, 6 Jul 2009."

The group village headman said the disease has affected almost every
family, with some having more than one patient. Chakulembera said
some patients died at Neno District Hospital but the majority
succumbed at their homes. "We are living in fear. When one is
attacked, we know he or she is going to die," he said.

Chakulembera said health officials from both Malawi and Mozambique
have been visiting the area "frequently" to monitor the situation.
"The Ministry of Health supplied us with Chlorine to add to the water
we use," confirmed Chakulembera. There is no piped water or
boreholes. Most of the houses are old round grass-thatched ones and
have no windows. People sleep together with animals in such houses,"
he said when asked to explain the living conditions of the people in
the affected area.

On another note, Mtemankhawa said he is living in fear for his life
after some of his villagers warned they would "deal with him. They
accuse me of being a wizard and that I am behind the deaths. They
make such allegations because they say I do not provide a solution.
But it is not true," he said.

He said villagers have since agitated for a witchdoctor to come to
the village to find the cause of the mysterious disease. He also said
grave-diggers have threatened to abandon their work, arguing they are
fed up with the frequent deaths. Dambe's advisor said the chief
advised fellow traditional leaders to tell people to stop sleeping in
the same house with animals and ensure that all dwelling units have
windows and pit latrines as preventive measures.

--
Communicated by:
ProMED-mail
<promed@promedmail.org>

[The above newswire describes a clinical picture that is difficult to
come to diagnostic conclusions on. Some of the symptoms might lead
one to think meningitis was the etiology, but the newswire mentions
that meningitis has been ruled out. Other symptoms might be
compatible with the more severe form of leptospirosis, although
arthralgias are described rather than myalgias, and jaundice is not
mentioned where it tends to be a predominant presenting symptom with
severe leptospirosis. According to the article, since the beginning
of May 2009, the overall attack rate has been 9.5 percent (103 cases
out of a total population of 1082) with a case fatality rate of 14.6
percent. Oftentimes when one reads newswires, the presumed risk
factors of disease mentioned helps to narrow down the etiologic
agent. In the above newswire this isn't really the case as it
mentions poor water and sanitation, and close proximity to animals,
risk factors for a large spectrum of microbial agents includi!
ng bacterial and viral agents. Note, that while this moderator is
mentioning microbial agents, the possibility of exposure to
environmental toxins has not been ruled out as yet either.

More information from knowledgeable sources in the region would be
greatly appreciated.

For a map of the Neno district of Malawi, see
<http://www.maplandia.com/malawi/southern/neno/>. For a map of the
Tsangano district of Mozambique, see
<http://www.maplandia.com/mozambique/tete/tsangano/>. If one zooms
out, one sees that the 2 districts are to the south of Lake Nyasa.

For the interactive HealthMap/ProMED map of Neno, Malawi, see
<http://healthmap.org/r/00Aa>, and for Tsangano Mozambique, see
<http://healthmap.org/r/00Ab>. - Mod.MPP]
..............................mpp/ejp/dk

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Re: Undiagnosed fatalities - 15 dead - Mozambique and Malawi - RFI

Re: Undiagnosed fatalities - 15 dead - Mozambique and Malawi - RFI

We'll have to wait a few days for the diagnosis out of the reference laboratories in South Africa. There may be more than one illness at work here, which may be complicating the diagnosis.
 
Outbreak of mystery illness in Mozambique (and Malawi)

Outbreak of mystery illness in Mozambique (and Malawi)

I thought I had posted the ProMed report below as undiagnosed fatalities on here somewhere, but the new report seems to give a possible diagnosis. Also of note in the new report is that the figures in the July 11th ProMed posting are as of July 3rd.

http://www.reliefweb.int/rw/rwb.nsf/db900SID/NSPR-7TZJ69?OpenDocument

Mozambique: Surveillance has been strengthened to the outbreak of the disease not yet identified which began on 24 June 2009 in the District Tsangano, Tete province which borders the district of Neno Malawi and seen as a viral meningo encephalitis . Au total 103 cas 14 d?c?s (l?talit?: 13,6%) ont ?t? notifi?s au 3 juillet 2009*. In total 103 cases 14 deaths (CFR 13.6%) were notified on 3 July 2009

----------------------------------------

http://www.promedmail.org/pls/otn/f...CHECK_DISPLAY,F2400_P1202_PUB_MAIL_ID:X,78306

UNDIAGNOSED FATALITIES - MALAWI, MOZAMBIQUE: REQUEST FOR INFORMATION
********************************************************************
A ProMED-mail post
<http://www.promedmail.org>
ProMED-mail is a program of the
International Society for Infectious Diseases
<http://www.isid.org>

Date: 11 Jul 2009
Source: Nation Online, Window on Malawi [edited]
<http://www.nationmw.net/newsdetail.asp?article_id=3384>


Strange disease hits Neno
-------------------------
An unknown disease has killed 15 people out of 103 patients since May
this year [2009] in 2 bordering villages of Mtemankhawa and Datson in
Malawi and Mozambique, respectively. Mtemankhawa Village, with a
total population of 753, is in the area of TA Dambe in Neno while
Datson Village, in the area of Chief Tsangano in Mozambique, has a
population of 329.

Traditional leaders in the area and Secretary for Health Chris
Kang'ombe have confirmed the occurrence of the unknown disease and
the deaths. "It is true that 15 people out of 103 cases have died so
far. 8 are from the Malawi side while 7 from Mozambique side. 5 are
admitted to Neno District Hospital," said Kang'ombe in an interview
yesterday. He described the disease as "not well known".

The PS said the ministry has already sent laboratory samples to South
Africa for analysis. The symptoms of the disease, according to
Kang'ombe, include stiff neck, dehydration, fever, headache, joint
pain, discomfort in abdomen and loss of voice. He ruled out meningitis.

While waiting for the results of the samples, he said, the ministry
is treating some patients with antibiotics and has supplied the
people with Chlorine because "they use unprotected wells for water."
He said the area is "very cold" and some people are forced not to
bathe for many days. He said some live together with animals in their
round grass-thatched houses which have no windows. "These could be
some contributing factors but it is yet to be seen," said Kang'ombe.
He said the ministry has also set up a treatment camp in the area to
handle minor cases.

Group Village Headman Chakulembera, who oversees Mtemankhawa Village,
said in an interview on Wednesday [8 Jul 2009] in Mwanza that those
affected by the disease develop stiff jaws, neck and have abdominal
pains. "It makes it difficult for them to eat," he said.
Chakulembera, who was flanked by village headman Mtemankhawa and T/A
Dambe's envoy MacDonald Chindimwe, said among those killed include 5
pupils, 3 from Chawe Primary School.

"On average, we have 3 or 4 deaths per week. People are worried about
the development because they cannot work in their wheat and Irish
potato gardens," said Chakulembera, who was supported by Mtemankhawa
who said: "The latest death was on Monday this week, 6 Jul 2009."

The group village headman said the disease has affected almost every
family, with some having more than one patient. Chakulembera said
some patients died at Neno District Hospital but the majority
succumbed at their homes. "We are living in fear. When one is
attacked, we know he or she is going to die," he said.

Chakulembera said health officials from both Malawi and Mozambique
have been visiting the area "frequently" to monitor the situation.
"The Ministry of Health supplied us with Chlorine to add to the water
we use," confirmed Chakulembera. There is no piped water or
boreholes. Most of the houses are old round grass-thatched ones and
have no windows. People sleep together with animals in such houses,"
he said when asked to explain the living conditions of the people in
the affected area.

On another note, Mtemankhawa said he is living in fear for his life
after some of his villagers warned they would "deal with him. They
accuse me of being a wizard and that I am behind the deaths. They
make such allegations because they say I do not provide a solution.
But it is not true," he said.

He said villagers have since agitated for a witchdoctor to come to
the village to find the cause of the mysterious disease. He also said
grave-diggers have threatened to abandon their work, arguing they are
fed up with the frequent deaths. Dambe's advisor said the chief
advised fellow traditional leaders to tell people to stop sleeping in
the same house with animals and ensure that all dwelling units have
windows and pit latrines as preventive measures.

--
Communicated by:
ProMED-mail
<promed@promedmail.org>

[The above newswire describes a clinical picture that is difficult to
come to diagnostic conclusions on. Some of the symptoms might lead
one to think meningitis was the etiology, but the newswire mentions
that meningitis has been ruled out. Other symptoms might be
compatible with the more severe form of leptospirosis, although
arthralgias are described rather than myalgias, and jaundice is not
mentioned where it tends to be a predominant presenting symptom with
severe leptospirosis. According to the article, since the beginning
of May 2009, the overall attack rate has been 9.5 percent (103 cases
out of a total population of 1082) with a case fatality rate of 14.6
percent. Oftentimes when one reads newswires, the presumed risk
factors of disease mentioned helps to narrow down the etiologic
agent. In the above newswire this isn't really the case as it
mentions poor water and sanitation, and close proximity to animals,
risk factors for a large spectrum of microbial agents includi!
ng bacterial and viral agents. Note, that while this moderator is
mentioning microbial agents, the possibility of exposure to
environmental toxins has not been ruled out as yet either.

More information from knowledgeable sources in the region would be
greatly appreciated.

For a map of the Neno district of Malawi, see
<http://www.maplandia.com/malawi/southern/neno/>. For a map of the
Tsangano district of Mozambique, see
<http://www.maplandia.com/mozambique/tete/tsangano/>. If one zooms
out, one sees that the 2 districts are to the south of Lake Nyasa.

For the interactive HealthMap/ProMED map of Neno, Malawi, see
<http://healthmap.org/r/00Aa>, and for Tsangano Mozambique, see
<http://healthmap.org/r/00Ab>. - Mod.MPP]
..............................mpp/ejp/dk
 
Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

This might be something unusual, as the US CDC is now getting involved. Also note the increase to 120 cases with 17 deaths.

http://www.apanews.net/public/apa.php?page=article&id_article=104797

Malawi - United States - Health



Des médecins américains au Malawi pour étudier une maladie mystérieuse American doctors in Malawi to investigate a mysterious disease

APA-Lilongwe (Malawi) Le gouvernement américain a dépêche cinq épidémiologistes du Centre de lute contre les maladies (CDC) basé à Atlanta, à Neno, une localité située dans le sud du Malawi pour enquêter sur l'apparition d'une maladie inconnue qui vient de se signaler. APA-Lilongwe (Malawi) The U.S. government has sent out five epidemiologists CENTRAL fight against the disease (CDC) based in Atlanta, Neno, a city located in southern Malawi to investigate the occurrence of a disease unknown has just been reported.

Selon un officiel américain, « Le groupe va commencer son travail avec le responsable de santé du District dans les localités concernées afin de mener une enquête complète sur l'apparition et rendre compte au ministre de la santé ». According to a U.S. official, "The group will begin its work with the head of Health District in the localities concerned to conduct a full investigation into the outbreak and report to the minister of health."

Depuis le mois de mai, une maladie mystérieuse a touché plus de 90 personnes à Neno et plus de 30 autres dans la localité voisine de Tsangano au Mozambique,avec un bilan de 17 morts souligne t-on. Since May, a mysterious disease has affected over 90 people in Neno and over 30 others in the nearby town of Tsangano in Mozambique, with a balance of 17 dead stresses there.

Les personnes touchées par cette maladie présentent des complications neurologiques. Those affected by this disease have neurological complications. Les essais de laboratoire et de radiologie préliminaires n'ont indiqué aucune maladie spécifique. Laboratory tests and preliminary X-ray indicated no specific disease.
 
Re: US sends five outbreak specialists to investigate Malawi mysterious outbreak

Re: US sends five outbreak specialists to investigate Malawi mysterious outbreak

US sends five outbreak specialists to investigate Malawi mysterious outbreak
Published July 24th, 2009 in World News, Africa News.
from Charles Mkula 5:32 am
date Jul 23, 2009 5:32 AM
subject US sends five outbreak specialists to investigate Malawi mysterious outbreak

US sends five outbreak specialists to investigate Malawi mysterious outbreak

By Charles Mkula

Lilongwe. The United States Government, through the Centers for
Disease Control (CDC), flown into Malawi five outbreak specialists to
work in Neno District, where an undiagnosed disease outbreak which has
so far killed 17 people since May.

Alison Liwanda, US Embassy Information Assistant said the specialists
are experts in environmental health and neurology and are working with
the Neno District Health Office to conduct a full investigation on the
outbreak.

The disease has affected 95 persons in the district in Malawi and 38
in neighbouring Tsangano District in Mozambique. Of the 17 deaths
reported nine have occured in Malawi, and eight in Mozambique.

According to eye witnesses, affected persons display unusual symptoms
with neurological complications. Patients admitted to hospital have
been treated with antibiotics and given supportive care including
rehydration.

The Malawi government earlier in the month sent blood samples for
initial laboratory and radiology examinations to South Africa, and
Zimbabwe but the results were not indicative of any specific illness.

New samples have now been sent to the Centers for Disease Control and
Prevention (CDC) in the USA for analysis, said Liwanda.

The Government of Malawi formally requested Epidemiological Aid
assistance from United States Government on July 15. Typically, the
CDC?s official response includes specialists in the relevant health
fields working with host country health officials to deal with
epidemiological investigation, diagnosis and laboratory support,
treatment and containment of the outbreak. The CDC works
collaboratively with the World Health Organization (WHO) and other
partners in country.


--------------------------------------------------------------------------------

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Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

If the US CDC is involved we should get a diagnosis really soon. Hopefully this should help to tell what some of the other outreaks are.
 
Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

And this article quotes 133 cases with 17 deaths.

http://www.dailytimes.bppmw.com/article.asp?ArticleID=13893

Neno outbreak affects 133
BY THERESA KASAWALA
12:48:37 - 24 July 2009

The mysterious epidemic that has plagued Neno continues to cause casualties. It has now infected 133 people and caused 17 deaths.

A press statement from the United States Government says the disease, which broke out in May this year, has infected 95 people in Neno and 38 in neighbouring Tsangano district in Mozambique.

?Affected persons display unusual symptoms with neurological complications. Patients admitted to the hospital have been treated with antibiotics and given supportive care including rehydration,? the statement states.

The development forced the Malawi government to seek help from the US government which has sent five specialists to investigate the outbreak.

?The specialists have expertise in environmental health and neurology. They arrived in the country on July 20, and are working with the District Health Officer and his team to conduct a full investigation on the outbreak,? the statement says.

It states that the experts were conducting epidemiological investigations, diagnosis and laboratory support, treatment and containment of the outbreak.

?Previous attempts to demystify the disease have proved futile because the blood samples collected by the ministry for testing in Malawi, Zimbabwe and South Africa all yielded negative,? says part of the statement.

According to the statement, new samples have been taken and are being shipped to the Centers for Disease Control and Prevention (CDC) in the USA for further analysis.

Secretary for Health Chris Kang?ombe confirmed in an interview yesterday that the specialists have already started their work.

Kang?ombe said the specialists would be in the country for two to three weeks.

?The results will be available immediately they finish their mission in the country,? the PS said.

The Government of Malawi formally requested Epidemiological Aid assistance from United States Government on July 15.
 
Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

If the US CDC is involved we should get a diagnosis really soon. Hopefully this should help to tell what some of the other outreaks are.

It might, or might not. I think there is a good chance that this one is going to be a novel encephalitis virus, possibly either waterborne or vector-borne. It is also possible that this one might not be infectious at all but could be exposure to some toxin. The rate of new cases has remained fairly steady, neither increasing or decreasing over the past couple weeks. That suggests an ongoing exposure.
 
Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

It might, or might not. I think there is a good chance that this one is going to be a novel encephalitis virus, possibly either waterborne or vector-borne. It is also possible that this one might not be infectious at all but could be exposure to some toxin. The rate of new cases has remained fairly steady, neither increasing or decreasing over the past couple weeks. That suggests an ongoing exposure.

So would an ongoing exposure, indicate that this is waterboune or vector bourne and cannot spread from person to person?
 
Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

So would an ongoing exposure, indicate that this is waterboune or vector bourne and cannot spread from person to person?

I'm leaning that way on this outbreak. The timing doesn't seem like person-to-person. But I don't know for sure. That attack rate is very high. The total population of the two villages is less than 1100 people, so you are now approaching a 15% attack rate. This outbreak seems very odd. The symptoms are bizarre and varied, and the fact that the South African labs couldn't find anything is odd. We learned last year that they could find even a novel virus quickly. But they didn't find anything here.

I do agree with you though, that the CDC's involvement makes this one the most likely of the undiagnosed neurological illnesses to get diagnosed.
 
Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

If anyone can diagnose it is the US CDC. They found swine flu.
 
Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

And ProMed strikes again on this one. I strongly agree with the bold statement. If there were an infectious agent, the South Africa labs would have found it. Also, the fact that the outbreak has been continuing for two months with new cases, but no geographical spread is not really consistent with an infectious agent.

http://www.promedmail.org/pls/otn/f..._BACK_PAGE,F2400_P1001_PUB_MAIL_ID:1000,78480

UNDIAGNOSED FATALITIES - MALAWI, MOZAMBIQUE (02): REQUEST FOR INFORMATION
*************************************************************************
A ProMED-mail post
<http://www.promedmail.org>
ProMED-mail is a program of the
International Society for Infectious Diseases
<http://www.isid.org>

Date: 24 Jul 2009
Source: Daily Times, Malawi
<http://www.dailytimes.bppmw.com/article.asp?ArticleID=13893>


Neno outbreak affects 133
-----------------
The mysterious epidemic that has plagued Neno continues to cause
casualties. It has now infected 133 people and caused 17 deaths.

A press statement from the United States Government says the disease,
which broke out in May this year [2009], has infected 95 people in
Neno and 38 in neighbouring Tsangano district in Mozambique.

"Affected persons display unusual symptoms with neurological
complications. Patients admitted to the hospital have been treated
with antibiotics and given supportive care including rehydration,"
the statement states.

The development forced the Malawi government to seek help from the US
government which has sent 5 specialists to investigate the outbreak.

"The specialists have expertise in environmental health and
neurology. They arrived in the country on [20 Jul 2009], and are
working with the District Health Officer and his team to conduct a
full investigation on the outbreak," the statement says.

It states that the experts were conducting epidemiological
investigations, diagnosis and laboratory support, treatment and
containment of the outbreak.

"Previous attempts to demystify the disease have proved futile
because the blood samples collected by the ministry for testing in
Malawi, Zimbabwe and South Africa all yielded negative," says part of
the statement.

According to the statement, new samples have been taken and are being
shipped to the Centers for Disease Control and Prevention (CDC) in
the USA for further analysis.

Secretary for Health Chris Kang'ombe confirmed in an interview
yesterday that the specialists have already started their work.

Kang'ombe said the specialists would be in the country for 2 to 3 weeks.

"The results will be available immediately they finish their mission
in the country," the PS said.

The Government of Malawi formally requested Epidemiological Aid
assistance from United States Government on [15 Jul 2009].

[Byline: Theresa Kasawala]

--
Communicated by:
ProMED-mail <promed@promedmail.org>

[There are now 133 cases and 17 deaths (case fatality rate [CFR] 12.8
percent). In the 1st newswire covered in a prior ProMED-mail posting
on 11 Jul 2009 (see archive number 20090711.2489), there were
reports of 103 cases with 15 deaths (CFR 14.6 percent). The earlier
report mentioned a total population at risk of 1082, so the overall
attack rate has increased from 9.5 percent to 12.3 percent. The
earlier report mentioned a symptom complex of "stiff neck,
dehydration, fever, headache, joint pain, discomfort in abdomen and
loss of voice". The above newswire doesn't provide much more on the
clinical picture other than to mention neurologic complications. The
mention that environmental health specialists and neurologists are on
the investigating team from the CDC in the USA suggests that
environmental etiologies are suspected.


More information on this outbreak from knowledgeable sources would be
greatly appreciated.

For a map of the Neno district of Malawi, see
<http://www.maplandia.com/malawi/southern/neno/>. For a map of the
Tsangano district of Mozambique, see
<http://www.maplandia.com/mozambique/tete/tsangano/>. If one zooms
out, one sees that the 2 districts are to the south of Lake Nyasa.

For the interactive HealthMap/ProMED map of Neno, Malawi, see
<http://healthmap.org/r/00Aa>, and for Tsangano Mozambique, see
<http://healthmap.org/r/00Ab>. - Mod.MPP]
 
Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

Note the increase to 19 deaths. The mention of a virus here is purely speculative; we have no idea what is causing this outbreak. The CDC ought to be able to give us some results soon. At the very least, they should be able to tell whether person-to-person spread is occurring, or whether the cases are sporadic.


http://www.thezimbabwean.co.uk/2009...s-in-malawi-to-investigate-bizarre-virus.html

US medical experts in Malawi to investigate bizarre virus
By David .Five American medical experts are in Malawi to conduct full investigations on a strange disease that has so far claimed lives of over 15 people in Neno district and the neighbouring Mozambique.


The five environmental health and neurology experts arrived in the country on July 20 and have already conducted a full investigation on the outbreak.

The United States (US) Embassy Office in Lilongwe said the specialists were brought into the country through the Centre for Disease Control (DCD) in response to a request from the Malawi Government for an intervention on the matter.

An undiagnosed disease broke out in Neno some three months ago and so far about 10 Malawians and nine Mozambicans have died after being attacked by the strange disease.

And close to 100 people in Neno district and about 40 in Tsangano district in Mozambique have so far been affected since the disease was first reported in May this year.

Affected people display unusual symptoms with neurological complications. However, patients with such symptoms have been treated with antibiotics and given supportive care including rehydration.

Initial laboratory and radiology examinations have not indicated any specific illness but the American experts have collected new samples which have been shipped to the Centers for Disease Control and Prevention (CDC) in the USA for analysis.

The Ministry of Health collected blood samples for further testing in Malawi, Zimbabwe and South Africa, whose results were negative.

“The CDC’s official response includes specialists in the relevant health fields working with host country health officials to deal with epidemiological investigation, diagnosis and laboratory support, treatment and containment of the outbreak,” says a media statement from the US Embassy.
 
Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

This might just be an echo story, especially since it only mentions 18 deaths and we had a story a couple weeks ago that mentioned 19. Also, it mentions that the samples have been sent to South Africa. Those samples came back empty weeks ago. The CDC has now had a team in the area since July 20, and still they haven't found anything. This is likely to be VERY unusual. I don't even think a novel virus would be unusual enough - the South African labs and CDC would have found that by now.

I don't know if orally (and the same word in Spanish) means foodborne or what we would call fecal-oral.

http://www.elfinanciero.com.mx/ElFi...cId=207475&docTipo=1&orderby=docid&sortby=ASC

18 people die on the border of Mozambique and Malawi
Internacional - Jueves 6 de agosto (08:40 hrs.) International - Thursday, August 6 (08:40 hrs.)




Fallecen a causa de una enfermedad desconocida Die from an unknown disease
Al parecer se transmite por vía oral Apparently transmitted orally


El Financiero en línea El Financiero Online

Maputo, 6 de agosto.- Dieciocho personas han muerto víctimas de una enfermedad desconocida en la frontera de Mozambique y Malaui, informó hoy el periódico mozambiqueño "O País". Maputo, August 6 .- Eighteen people have died of an unknown disease at the border of Malawi and Mozambique, Mozambican newspaper reported today "O Pais".

Según el rotativo, que cita fuentes médicas, los hospitales de la zona están a la espera de recibir los resultados de los análisis que están siendo efectuados en Sudáfrica. According to the newspaper, citing medical sources, hospitals in the area are awaiting the results of the analysis being carried out in South Africa.

"La última víctima mortal se produjo en las últimas 48 horas en el hospital del distrito de Neno, en Malawi", donde además están ingresados varios pacientes mozambiqueños, informa el diario. "The last fatality occurred in the last 48 hours in Neno District Hospital in Malawi, where many patients are also admitted Mozambicans, the newspaper reported.

Las autoridades, que pronostican que la enfermedad se transmite por vía oral, han confirmado que la dolencia afecta al sistema nervioso central, que causa pérdidas de voz y dolores abdominales, y que sus síntomas pueden confundirse con los de la malaria. The authorities predict that the disease is transmitted orally, have confirmed that the disease affects the central nervous system, causing loss of voice and abdominal pain, and symptoms can be confused with those of malaria.

Carla Mosse, médico de la provincia de Tsangano, dijo que podría ser una dolencia causada por las bajas temperaturas que se registran en esa zona del país. Carla Mosse, medical Tsangano province, said a condition could be caused by the low temperatures recorded in that region. (Con información de EFE/CFE) (With information from Reuters / CFE)
 
Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

So now we are up to 142 cases with 20 deaths. The CDC has been investigating this for over a month, and still hasn't found anything. It does appear that there have only been about 9 news cases in the past month.

http://allafrica.com/stories/200908160001.html

Mozambique: Mysterious Disease Kills 20 in Tete
16 August 2009

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Maputo — An outbreak of a strange disease in the district of Tsangano, in the central Mozambican province of Tete, has killed at least 20 people since it was first reported last May.

At present there some 142 infected, reported Mozambique's state television TVM on Saturday.

The health authorities in Tete are concerned with the outbreak of this disease, since it is still unclear its real source.

According to the health authorities, they are still waiting for laboratory results of the samples sent to the neighbouring South Africa

The disease attacks the central nervous system. In the early the stages its symptoms are similar to malaria, including abdominal pain, and loss of voice in its advanced stages.

As the origin of the disease is still unknown, the team of doctors both national and foreign working in the region are just prescribing antibiotics to the patients.

Meanwhile, the health authorities, in partnership with other relevant entities, including community leaders, have already launched a sanitation campaign in the affected communities.

There is a suspicion that the disease may have its origin in the region of Maujete, district of Tsangano, in the province of Tete, which still lacks a health centre.

Some of the patients have been taken to a district hospital in Neno, in neighbouring Malawi, for treatment.

The province of Tete shares the same border with Malawi.
 
Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

I think we should change the name of this thread to Strange Disease in Mozambique as it now appears unlikely that bacterial meningitis or viral encephalitis is involved. The thread should probably also be moved back to the "Emerging Diseases.." forum. Someone should also send the new article to ProMed.
 
Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

An older article that I missed. This one claimed 137 cases as of August 6, so 142 yesterday would be 5 new cases in 9 days.

http://www.rm.co.mz/noticiasarquivo/06Agosto/Doencaestranhamatanovepessoasemtete.html

Doen?a estranha mata nove pessoas em Tete
06/08/09

Um total de nove pessoas morreram por causa de uma doen?a estranha que eclodiu em meados de Maio passado no distrito de Tsangano, prov?ncia de Tete, Centro de Mocambique

At? agora, n?o se conhece a referida doen?a, j? que ainda se espera pelos resultados das an?lises laboratoriais das amostras enviadas para a vizinha Africa do Sul. Mas ela afecta o sistema nervoso central e ? caracterizada, na sua fase inicial, por sintomas semelhantes aos da mal?ria, dores abdominais e perda de voz (j? no seu estado avan?ado).

Mas suspeita-se que a mesma ter? eclodido em Maujete, uma zona de Tsangano desprovida de uma unidade sanit?ria, sendo por isso que os doentes foram evacuados para um hospital do vizinho distrito de Neno, Malawi, onde agora encontram-se internados cinco mo?ambicanos e outros nove cidad?os daquele pa?s.

De acordo com os novos dados, o n?mero de mortos passou para 18, sendo a outra metade de cidad?os malawianos, dos 137 casos cumulativos da doen?a registados at? agora, segundo escreve o jornal ?O Pa?s?.

N?o conhecendo as reais causas da doen?a, a equipa de m?dicos (nacionais e estrangeiros) em actividade naquela unidade sanit?ria limita-se a fornecer antibi?ticos aos doentes.

Entretanto, a m?dica-chefe da prov?ncia de Tete, Carla Mosse, avan?ou a hip?tese de a doen?a ser encefalite viral provocadas pelas baixas temperaturas registadas naquele ponto do pa?s, aliadas as prec?rias condi??es de higiene e de habita??o.

Por essa raz?o, o sector da sa?de, em parceria com outras entidades relevantes, incluindo l?deres comunit?rios, est? a desencadear uma campanha de saneamento do meio nas comunidades afectadas pela doen?a, medidas que parece n?o terem sido tomadas preventivamente.

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Strange disease kills nine people in Tete
06/08/09

A total of nine people died because of a strange disease that broke out in mid-May last Tsangano the district, province of Tete, central Mozambique

Until now, we do not know the disease, as if waiting for the results of laboratory analysis of samples sent to neighboring South Africa but it affects the central nervous system and is characterized in its early stage by symptoms similar to malaria, abdominal pain and loss of voice (already in its advanced stage).

But it is suspected that it will have hatched in Maujete, an area devoid of Tsangano a health unit, and why the patients were evacuated to a hospital in the neighboring district of Neno, Malawi, where they are now hospitalized and five Mozambicans nine other citizens of that country.

According to new data, the number of dead rose to 18, the other half of Malawi citizens, of the 137 cumulative cases of the disease so far, according to the newspaper writes "The Country".

Not knowing the real causes of disease, the team of doctors (and foreign) in activity in that health unit is limited to provide antibiotics to patients.

However, the medical chief of the province of Tete, Carla Mosse, advanced the hypothesis that the disease is viral encephalitis caused by low temperatures recorded in that section of the country, along the precarious conditions of health and housing.

Therefore, the health sector, in partnership with other relevant organizations, including community leaders, is to launch a campaign to clean up the environment in communities affected by the disease, measures that seem to have been taken preventively.
 
Re: Outbreak of mystery illness in Mozambique (and Malawi)

Re: Outbreak of mystery illness in Mozambique (and Malawi)

Thank you for merging the threads.

http://www.thetimes.co.za/News/Article.aspx?id=1051140

Mozambique outbreak kills 20
Sapa Published:Aug 17, 2009

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An unidentified disease in the Tsangano district of Mozambique?s north-western Tete province has claimed 20 lives since May, the daily independent O Pais reported today.

According to the Maputo-based paper, health authorities have sent samples to South Africa and are still waiting for laboratory results.

The disease has claimed 20 lives out of 142 cases reported since May, the report said citing health authorities in the province.

The disease attacks the central nervous system.

In the early the stages its symptoms are similar to malaria, including abdominal pain. In its advanced stage, one of the symptoms is the loss of voice.

The paper suggested the outbreak of the disease could have begun in the region of Maujete, in Tsangano, where there are no nearby clinics.

Some of the patients have been taken to a district hospital in Neno, in neighbouring Malawi, for treatment, said the paper.
 
Re: Outbreak of mystery illness in Mozambique (and Malawi)

Re: Outbreak of mystery illness in Mozambique (and Malawi)

From a Mozambican source (repeated at either link). This is a recent post (September 1), but does not have the latest numbers. This seems unlikely to be spread person-to-person by breath, as suspected in this post, as there would have been many more cases by now, with this outbreak well into its fourth (fifth?) month. There were 103 cases by July 3, but so far only about 40 since.

I have been expecting a new MSM article on this for the past week (we had been averaging one every 10 days), but so far there has not been one since August 17.

http://rcm.amazon.com/e/cm?t=fernanddasilvain&o=1&p=27&l=qs1&f=ifr

http://www.canalmoz.com/default.jsp?file=ver_artigo&nivel=1&id=6&idRec=6253

Doença estranha mata 20 em Tete Strange disease kills 20 in Tete
A médica chefe provincial diz haver suspeitas de que a doença seja “encefalite viral”, mas alega que não passa de suspeita. The provincial medical chief says there are suspicions that the disease is "viral encephalitis", but argues that there is only suspicion. Justifica: “Ainda não existem exames médicos que o provem”. Justified: "There are no medical tests to prove that."

Uma doença estranha está a matar, a norte da província de Tete, no noroeste do País. O fenómeno arrasta-se desde Abril do ano corrente. A strange disease is killing, the northern province of Tete in the northwest of the country The phenomenon creeps since April this year. Já foi responsável pela morte de 20 pessoas, até ao presente momento. It has been responsible for killing 20 people, until now. A doença tem vários sintomas associados: dor de cabeça, vómitos, diarreias e perturbações psicológicas. The disease has many symptoms: headache, vomiting, diarrhea and psychological disorders. Dos 137 casos diagnosticados pelos serviços da saúde na província, registaram-se 20 óbitos nos últimos três meses: Nove (9) moçambicanos e onze (11) malawianos. Of the 137 cases diagnosed by health services in the province, there were 20 deaths in the past three months: Nine (9) Mozambicans and eleven (11) Malawians.


Apesar dos primeiros casos terem sido identificados em Abril, as autoridades sanitárias só identificaram a doença que está a matar em Tete, no princípio de Julho último. Although the first cases were identified in April, health authorities only identified the disease that is killing in Tete, in early July. Foi detectada, em grande parte, em imigrantes malawianos. Was detected largely in Malawian immigrants.
A povoação de Mwenjate, distrito de Tsangano, que faz fronteira com o Malawi, é das mais afectadas pelo surto. The village of Mwenjate, Tsangano district, which borders with Malawi, is the most affected by the outbreak.

Formas de contaminação Forms of contamination

Ainda não está provada a forma de transmissão desta doença, mas há suspeitas de que se propaga por meio de contacto interpessoal, através da respiração. Although there is no proven way of transmission of this disease, but there are suspicions that spreads through interpersonal contact, through the breath.

Refira-se que alguns doentes moçambicanos contaminados por esta doença não estão a ser tratados no País. Recebem tratamento no Hospital de Neno, no Malawi, pelo facto de na povoação de Mwenjate existir apenas uma unidade sanitária, que se torna incapaz de responder ao surto da doença. It should be noted that some patients Mozambicans infected by this disease are not being treated in the country being treated in hospital in Neno, Malawi, the fact that the village of Mwenjate there is only one facility that is unable to respond to the outbreak disease.

A médica chefe da província de Tete, Carla Mosse, disse que a doença está a afectar grande número de cidadãos no povoado de Mwenjate, pelo facto desta ser uma zona de muito frio, e montanhosa, onde as pessoas estão sempre juntas nas cabanas a aquecerem-se ao fogo. The medical chief of the province of Tete, Carla Mosse, said the disease is affecting many people in the village of Mwenjate, because this is an area of very cold, and mountain, where people are always together in the cabins warm to the fire.

Ainda de acordo com Carla Mosse, já foi destacada para aquela povoação, uma equipa de socorrer aos pacientes. Also according to Carla Mosse, already deployed in that village, a team to rescue the patients. Os casos mais graves, segundo a médica chefe de Tete são evacuados para o Hospital de Neno, no vizinho Malawi. The most serious cases, according to the medical chief of Tete are evacuated to the Hospital of Neno, in neighboring Malawi.

A médica disse-nos haver suspeitas de que a doença seja “encefalite viral”, mas alega que não passa de suspeita. The doctor told us there is a suspicion that the disease is "viral encephalitis", but argues that there is only suspicion. Justifica: “Ainda não existem exames médicos que o provem”. Justified: "There are no medical tests to prove that."

Tratamento Treatment

Segundo a médica chefe da província de Tete, para além do pessoal de saúde nacional, já se encontra naquela província, uma equipe dos Estados Unidos de América, que “tem grande experiência e meios para mitigar a doença”. According to the medical chief of the province of Tete, in addition to the national health personnel, is already in that province, a team of United States of America, which "has great experience and means to mitigate the disease."

“Por enquanto estamos a fazer o tratamento com antibióticos simples e também usamos os mais complexos para os casos complicados”, conclui Carla Mosse. "For now we are doing the simple course of antibiotics and also use the more complex for the complicated cases," concludes Carla Mosse. ( José Mirione ) (José Mirion)

CANALMOZ – 01.09.2009 Canalmoz - 01/09/2009

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