tetano
Editor, Senior Moderator
Turk J Med Sci
. 2020 Oct 6.
doi: 10.3906/sag-2006-203. Online ahead of print.
Cerebral hemodynamic alterations in patients with Covid-19
Alİ Riza Sonkaya, Bİlgİn ?zt?rk, ?mer KaradaŞ
Abstract
Background/aim: Coronavirus 2019 disease (Covid-19) was first seen in December 2019 and afterwards it became a pandemic. Several systemic involvements have been reported in Covid-19 patients. In this study, it was aimed to investigate the cerebrovascular hemodynamics in patients with Covid-19.
Materials and methods: The sample of this study was conducted on 20 patients hospitalized in our clinic diagnosed with Covid-19 via PCR modality and 20 healthy volunteers of similar age and sex. Bilateral middle cerebral arteries were investigated with Transcranial Doppler Ultrasonography. Basal serebral blood flow velocities and vasomotor reactivity rates were determined and compared as statistically.
Results: When patient and control groups were compared, the mean blood flow velocity was found to be higher in Covid-19 patients than the healthy volunteers and it was statistically significant (p = 0.00). The mean vasomotor reactivity rates values were found to be lower in Covid-19 group than the healthy group and also it was statistically significant (p = 0.00).
Conclusion: An increase in cerebral basal blood velocity and a decrease in vasomotor reactivity rates in patients with Covid-19 can be considered as an indicator of dysfunction of cerebral hemodynamics in central nervous system and this can be evaluated as a result of endothelial dysfunction.
Keywords: Blood flow velocity; Covid-19; SARS-Cov-2; Vasomotor reactivity.
. 2020 Oct 6.
doi: 10.3906/sag-2006-203. Online ahead of print.
Cerebral hemodynamic alterations in patients with Covid-19
Alİ Riza Sonkaya, Bİlgİn ?zt?rk, ?mer KaradaŞ
- PMID: 33021761
- DOI: 10.3906/sag-2006-203
Abstract
Background/aim: Coronavirus 2019 disease (Covid-19) was first seen in December 2019 and afterwards it became a pandemic. Several systemic involvements have been reported in Covid-19 patients. In this study, it was aimed to investigate the cerebrovascular hemodynamics in patients with Covid-19.
Materials and methods: The sample of this study was conducted on 20 patients hospitalized in our clinic diagnosed with Covid-19 via PCR modality and 20 healthy volunteers of similar age and sex. Bilateral middle cerebral arteries were investigated with Transcranial Doppler Ultrasonography. Basal serebral blood flow velocities and vasomotor reactivity rates were determined and compared as statistically.
Results: When patient and control groups were compared, the mean blood flow velocity was found to be higher in Covid-19 patients than the healthy volunteers and it was statistically significant (p = 0.00). The mean vasomotor reactivity rates values were found to be lower in Covid-19 group than the healthy group and also it was statistically significant (p = 0.00).
Conclusion: An increase in cerebral basal blood velocity and a decrease in vasomotor reactivity rates in patients with Covid-19 can be considered as an indicator of dysfunction of cerebral hemodynamics in central nervous system and this can be evaluated as a result of endothelial dysfunction.
Keywords: Blood flow velocity; Covid-19; SARS-Cov-2; Vasomotor reactivity.