tetano
Editor, Senior Moderator
Transplant Proc
. 2020 Dec 18;S0041-1345(20)32900-6.
doi: 10.1016/j.transproceed.2020.10.048. Online ahead of print.
COVID-19 Manifesting as Renal Allograft Dysfunction, Acute Pancreatitis, and Thrombotic Microangiopathy: A Case Report
Tiana Jespersen Nizamic[SUP] 1 [/SUP], Yihung Huang[SUP] 1 [/SUP], Muna Alnimri[SUP] 1 [/SUP], Mingyu Cheng[SUP] 2 [/SUP], Ling-Xin Chen[SUP] 1 [/SUP], Kuang-Yu Jen[SUP] 3 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) is associated with high morbidity and mortality worldwide in both the general population and kidney transplant recipients. Acute kidney injury is a known complication of COVID-19 and appears to most commonly manifest as acute tubular injury on renal biopsy. Coagulopathy associated with COVID-19 is a known but poorly understood complication that has been reported to cause thrombotic microangiopathy on rare occasions in native kidneys of patients with COVID-19. Here, we report the first case of biopsy-proven thrombotic microangiopathy in a kidney transplant recipient with COVID-19 who developed acute pancreatitis and clinical features of microangiopathic hemolytic anemia. The patient recovered with supportive care alone.
. 2020 Dec 18;S0041-1345(20)32900-6.
doi: 10.1016/j.transproceed.2020.10.048. Online ahead of print.
COVID-19 Manifesting as Renal Allograft Dysfunction, Acute Pancreatitis, and Thrombotic Microangiopathy: A Case Report
Tiana Jespersen Nizamic[SUP] 1 [/SUP], Yihung Huang[SUP] 1 [/SUP], Muna Alnimri[SUP] 1 [/SUP], Mingyu Cheng[SUP] 2 [/SUP], Ling-Xin Chen[SUP] 1 [/SUP], Kuang-Yu Jen[SUP] 3 [/SUP]
Affiliations
- PMID: 33436168
- DOI: 10.1016/j.transproceed.2020.10.048
Abstract
Coronavirus disease 2019 (COVID-19) is associated with high morbidity and mortality worldwide in both the general population and kidney transplant recipients. Acute kidney injury is a known complication of COVID-19 and appears to most commonly manifest as acute tubular injury on renal biopsy. Coagulopathy associated with COVID-19 is a known but poorly understood complication that has been reported to cause thrombotic microangiopathy on rare occasions in native kidneys of patients with COVID-19. Here, we report the first case of biopsy-proven thrombotic microangiopathy in a kidney transplant recipient with COVID-19 who developed acute pancreatitis and clinical features of microangiopathic hemolytic anemia. The patient recovered with supportive care alone.