tetano
Editor, Senior Moderator
Transpl Infect Dis
. 2020 Jul 23;e13423.
doi: 10.1111/tid.13423. Online ahead of print.
Influence of Immunosuppression on Seroconversion Against SARS-Cov-2 in Two Kidney Transplant Recipients
Aileen X Wang[SUP] 1 [/SUP], Orlando Quintero Cardona[SUP] 2 [/SUP], Dora Y Ho[SUP] 2 [/SUP], Stephan Busque[SUP] 3 [/SUP], Colin R Lenihan[SUP] 1 [/SUP]
Affiliations
Abstract
Solid organ transplant recipients are at risk for infectious complications due to chronic immunosuppression. The outbreak of Coronavirus Disease 2019 (COVID-19) in United States has raised growing concerns for the transplant patient population. We seek to add to the current limited literature on COVID-19 in transplant recipients by describing the clinical course of two kidney transplant recipients with SARS-Cov-2 infection monitored by both RT-PCR and serology. Through careful adjustment of their immunosuppression regimen, both patients had excellent recovery with intact graft function and development of anti-SARS-Cov-2 antibodies.
Keywords: COVID-19; RT-PCR; SARS-Cov-2; antibodies; immunosuppression; seroconversion.
. 2020 Jul 23;e13423.
doi: 10.1111/tid.13423. Online ahead of print.
Influence of Immunosuppression on Seroconversion Against SARS-Cov-2 in Two Kidney Transplant Recipients
Aileen X Wang[SUP] 1 [/SUP], Orlando Quintero Cardona[SUP] 2 [/SUP], Dora Y Ho[SUP] 2 [/SUP], Stephan Busque[SUP] 3 [/SUP], Colin R Lenihan[SUP] 1 [/SUP]
Affiliations
- PMID: 32701196
- DOI: 10.1111/tid.13423
Abstract
Solid organ transplant recipients are at risk for infectious complications due to chronic immunosuppression. The outbreak of Coronavirus Disease 2019 (COVID-19) in United States has raised growing concerns for the transplant patient population. We seek to add to the current limited literature on COVID-19 in transplant recipients by describing the clinical course of two kidney transplant recipients with SARS-Cov-2 infection monitored by both RT-PCR and serology. Through careful adjustment of their immunosuppression regimen, both patients had excellent recovery with intact graft function and development of anti-SARS-Cov-2 antibodies.
Keywords: COVID-19; RT-PCR; SARS-Cov-2; antibodies; immunosuppression; seroconversion.