tetano
Editor, Senior Moderator
Trans R Soc Trop Med Hyg
. 2022 Sep 24;trac089.
doi: 10.1093/trstmh/trac089. Online ahead of print.
Multicountry study of SARS-CoV-2 and associated risk factors among healthcare workers in Côte d'Ivoire, Burkina Faso and South Africa
Sarah Kribi[SUP] 1 [/SUP], Fidèle Touré[SUP] 2 [/SUP], Adriano Mendes[SUP] 3 [/SUP], Soufiane Sanou[SUP] 4 [/SUP], Arsène Some[SUP] 4 [/SUP], Abdoul M Aminou[SUP] 2 [/SUP], Essia Belarbi[SUP] 1 [/SUP], Rosemary Griessel[SUP] 5 6 [/SUP], Arsène Hema[SUP] 7 [/SUP], Firmin Kabore[SUP] 4 [/SUP], Paul Pitzinger[SUP] 1 [/SUP], Amy Strydom[SUP] 3 [/SUP], Ann Christin Vietor[SUP] 1 [/SUP], Korotimi Traoré[SUP] 4 [/SUP], Arsène Zongo[SUP] 4 [/SUP], Etilé A Anoh[SUP] 2 [/SUP], Marica Grossegesse[SUP] 1 [/SUP], Natalie Hofmann[SUP] 1 [/SUP], Soumeya Ouangraoua[SUP] 4 [/SUP], Armel Poda[SUP] 7 [/SUP], Thérèse Kagone[SUP] 4 [/SUP], Grit Schubert[SUP] 1 [/SUP], Tim Eckmanns[SUP] 1 [/SUP], Marietjie Venter[SUP] 3 [/SUP], Fabian Leendertz[SUP] 1 [/SUP], Chantal Akoua-Koffi[SUP] 2 [/SUP], Sara Tomczyk[SUP] 1 [/SUP]
Affiliations
Abstract
Background: Reports on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread across Africa have varied, including among healthcare workers (HCWs). This study assessed the comparative SARS-CoV-2 burden and associated risk factors among HCWs in three African countries.
Methods: A multicentre study was conducted at regional healthcare facilities in Côte d'Ivoire (CIV), Burkina Faso (BF) and South Africa (SA) from February to May 2021. HCWs provided blood samples for SARS-CoV-2 serology and nasopharyngeal/oropharyngeal swabs for testing of acute infection by polymerase chain reaction and completed a questionnaire. Factors associated with seropositivity were assessed with logistic regression.
Results: Among 719 HCWs, SARS-CoV-2 seroprevalence was 34.6% (95% confidence interval 31.2 to 38.2), ranging from 19.2% in CIV to 45.7% in BF. A total of 20 of 523 (3.8%) were positive for acute SARS-CoV-2 infection. Female HCWs had higher odds of SARS-CoV-2 seropositivity compared with males, and nursing staff, allied health professionals, non-caregiver personnel and administration had higher odds compared with physicians. HCWs also reported infection prevention and control (IPC) gaps, including 38.7% and 29% having access to respirators and IPC training, respectively, in the last year.
Conclusions: This study was a unique comparative HCW SARS-CoV-2 investigation in Africa. Seroprevalence estimates varied, highlighting distinctive population/facility-level factors affecting COVID-19 burden and the importance of established IPC programmes to protect HCWs and patients.
Keywords: Africa; COVID-19; SARS-CoV-2; healthcare workers; infection prevention and control; serology.
. 2022 Sep 24;trac089.
doi: 10.1093/trstmh/trac089. Online ahead of print.
Multicountry study of SARS-CoV-2 and associated risk factors among healthcare workers in Côte d'Ivoire, Burkina Faso and South Africa
Sarah Kribi[SUP] 1 [/SUP], Fidèle Touré[SUP] 2 [/SUP], Adriano Mendes[SUP] 3 [/SUP], Soufiane Sanou[SUP] 4 [/SUP], Arsène Some[SUP] 4 [/SUP], Abdoul M Aminou[SUP] 2 [/SUP], Essia Belarbi[SUP] 1 [/SUP], Rosemary Griessel[SUP] 5 6 [/SUP], Arsène Hema[SUP] 7 [/SUP], Firmin Kabore[SUP] 4 [/SUP], Paul Pitzinger[SUP] 1 [/SUP], Amy Strydom[SUP] 3 [/SUP], Ann Christin Vietor[SUP] 1 [/SUP], Korotimi Traoré[SUP] 4 [/SUP], Arsène Zongo[SUP] 4 [/SUP], Etilé A Anoh[SUP] 2 [/SUP], Marica Grossegesse[SUP] 1 [/SUP], Natalie Hofmann[SUP] 1 [/SUP], Soumeya Ouangraoua[SUP] 4 [/SUP], Armel Poda[SUP] 7 [/SUP], Thérèse Kagone[SUP] 4 [/SUP], Grit Schubert[SUP] 1 [/SUP], Tim Eckmanns[SUP] 1 [/SUP], Marietjie Venter[SUP] 3 [/SUP], Fabian Leendertz[SUP] 1 [/SUP], Chantal Akoua-Koffi[SUP] 2 [/SUP], Sara Tomczyk[SUP] 1 [/SUP]
Affiliations
- PMID: 36153637
- DOI: 10.1093/trstmh/trac089
Abstract
Background: Reports on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread across Africa have varied, including among healthcare workers (HCWs). This study assessed the comparative SARS-CoV-2 burden and associated risk factors among HCWs in three African countries.
Methods: A multicentre study was conducted at regional healthcare facilities in Côte d'Ivoire (CIV), Burkina Faso (BF) and South Africa (SA) from February to May 2021. HCWs provided blood samples for SARS-CoV-2 serology and nasopharyngeal/oropharyngeal swabs for testing of acute infection by polymerase chain reaction and completed a questionnaire. Factors associated with seropositivity were assessed with logistic regression.
Results: Among 719 HCWs, SARS-CoV-2 seroprevalence was 34.6% (95% confidence interval 31.2 to 38.2), ranging from 19.2% in CIV to 45.7% in BF. A total of 20 of 523 (3.8%) were positive for acute SARS-CoV-2 infection. Female HCWs had higher odds of SARS-CoV-2 seropositivity compared with males, and nursing staff, allied health professionals, non-caregiver personnel and administration had higher odds compared with physicians. HCWs also reported infection prevention and control (IPC) gaps, including 38.7% and 29% having access to respirators and IPC training, respectively, in the last year.
Conclusions: This study was a unique comparative HCW SARS-CoV-2 investigation in Africa. Seroprevalence estimates varied, highlighting distinctive population/facility-level factors affecting COVID-19 burden and the importance of established IPC programmes to protect HCWs and patients.
Keywords: Africa; COVID-19; SARS-CoV-2; healthcare workers; infection prevention and control; serology.