tetano
Editor, Senior Moderator
Ther Apher Dial
. 2026 May 19.
doi: 10.1002/1744-9987.70157. Online ahead of print.
Initial Symptom Duration Among Vulnerable Dialysis Patients Hospitalized for Long-Term Care Correlates With Post-COVID-19 Poor Prognosis
Takayuki Hirai[SUP] 1 [/SUP], Masataka Banshodani[SUP] 2 [/SUP], Yusuke Kawai[SUP] 2 [/SUP], Nobuaki Shiraki[SUP] 1 [/SUP], Shingo Kashimura[SUP] 1 [/SUP], Atsuo Takemasa[SUP] 1 [/SUP], Seiji Marubayashi[SUP] 1 [/SUP], Michinori Imazu[SUP] 1 [/SUP], Shinichiro Tsuchiya[SUP] 2 [/SUP], Takao Masaki[SUP] 3 [/SUP], Hideki Kawanishi[SUP] 2 [/SUP]
Affiliations
Introduction: Among vulnerable dialysis patients, initial symptom duration of coronavirus disease 2019 (COVID-19) has not been investigated extensively.
Methods: We analyzed 153 dialysis patients with COVID-19 in a long-term care hospital between February 2022 and August 2023. We investigated the association between the delayed resolution of the initial symptoms (≥ 6 days), including fever or upper respiratory symptoms, and worse outcomes. These outcomes were defined as either a decrease in the Geriatric Nutritional Risk Index of ≥ 3.6% at 3 months after onset, or all-cause death within 3 months.
Results: The duration of the initial symptoms was associated with worse outcomes. This association remained significant after adjustment for patient background, COVID-19 severity, C-reactive protein levels at onset, vaccination, and antiviral therapy, using multivariate analysis.
Conclusion: The duration of the initial symptoms may be a useful indicator for predicting the poor prognosis, including nutritional deterioration after COVID-19, among vulnerable dialysis patients.
Keywords: coronavirus disease 2019; dialysis; nutritional status; symptom duration.
. 2026 May 19.
doi: 10.1002/1744-9987.70157. Online ahead of print.
Initial Symptom Duration Among Vulnerable Dialysis Patients Hospitalized for Long-Term Care Correlates With Post-COVID-19 Poor Prognosis
Takayuki Hirai[SUP] 1 [/SUP], Masataka Banshodani[SUP] 2 [/SUP], Yusuke Kawai[SUP] 2 [/SUP], Nobuaki Shiraki[SUP] 1 [/SUP], Shingo Kashimura[SUP] 1 [/SUP], Atsuo Takemasa[SUP] 1 [/SUP], Seiji Marubayashi[SUP] 1 [/SUP], Michinori Imazu[SUP] 1 [/SUP], Shinichiro Tsuchiya[SUP] 2 [/SUP], Takao Masaki[SUP] 3 [/SUP], Hideki Kawanishi[SUP] 2 [/SUP]
Affiliations
- PMID: 42156178
- DOI: 10.1002/1744-9987.70157
Introduction: Among vulnerable dialysis patients, initial symptom duration of coronavirus disease 2019 (COVID-19) has not been investigated extensively.
Methods: We analyzed 153 dialysis patients with COVID-19 in a long-term care hospital between February 2022 and August 2023. We investigated the association between the delayed resolution of the initial symptoms (≥ 6 days), including fever or upper respiratory symptoms, and worse outcomes. These outcomes were defined as either a decrease in the Geriatric Nutritional Risk Index of ≥ 3.6% at 3 months after onset, or all-cause death within 3 months.
Results: The duration of the initial symptoms was associated with worse outcomes. This association remained significant after adjustment for patient background, COVID-19 severity, C-reactive protein levels at onset, vaccination, and antiviral therapy, using multivariate analysis.
Conclusion: The duration of the initial symptoms may be a useful indicator for predicting the poor prognosis, including nutritional deterioration after COVID-19, among vulnerable dialysis patients.
Keywords: coronavirus disease 2019; dialysis; nutritional status; symptom duration.