tetano
Editor, Senior Moderator
Ther Adv Respir Dis
. 2023 Jan-Dec;17:17534666231162252.
doi: 10.1177/17534666231162252.
Effect of coronaviruses on blood vessel permeability: potential therapeutic targets
Nicolle R Machado[SUP] 1 [/SUP], Karina T Dias[SUP] 1 [/SUP], Bryan F S Cortes[SUP] 1 [/SUP], Stephen F Rodrigues[SUP] 2 [/SUP]
Affiliations
Abstract
Coronavirus-induced diseases have afflicted humanity for several decades. This scenario was aggravated by the emergence of the coronavirus disease 2019 (named COVID-19) in Wuhan, China, in December 2019. Since then, COVID-19 has killed millions of people worldwide, probably the most devastating pandemic since HIV/AIDS. This review aimed to bring together important updated aspects related to coronavirus-induced diseases and the enhanced vascular permeability observed mainly in the lungs of affected people. The dysregulated vascular permeability in the lungs is of fundamental importance for coronaviruses-caused morbidity and mortality. Thus, as described in this review, it is a target of new and old drugs.
Keywords: blood vessels; respiratory distress; vascular permeability; virus infection.
. 2023 Jan-Dec;17:17534666231162252.
doi: 10.1177/17534666231162252.
Effect of coronaviruses on blood vessel permeability: potential therapeutic targets
Nicolle R Machado[SUP] 1 [/SUP], Karina T Dias[SUP] 1 [/SUP], Bryan F S Cortes[SUP] 1 [/SUP], Stephen F Rodrigues[SUP] 2 [/SUP]
Affiliations
- PMID: 37067023
- DOI: 10.1177/17534666231162252
Abstract
Coronavirus-induced diseases have afflicted humanity for several decades. This scenario was aggravated by the emergence of the coronavirus disease 2019 (named COVID-19) in Wuhan, China, in December 2019. Since then, COVID-19 has killed millions of people worldwide, probably the most devastating pandemic since HIV/AIDS. This review aimed to bring together important updated aspects related to coronavirus-induced diseases and the enhanced vascular permeability observed mainly in the lungs of affected people. The dysregulated vascular permeability in the lungs is of fundamental importance for coronaviruses-caused morbidity and mortality. Thus, as described in this review, it is a target of new and old drugs.
Keywords: blood vessels; respiratory distress; vascular permeability; virus infection.