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The use of prophylactic nebulized liposomal amphotericin B to reduce the risk of CAPA in mechanically ventilated COVID-19 patients on ICU in a large U

M

Mary Wilson

Well-known member
Published: 06 March 2023

https://doi.org/10.1093/jac/dkad054

Anna Wild, Vicki Fleming, Lauren Rose, Amelia Joseph

Pulmonary aspergillosis is now recognized as a significant cause of morbidity and mortality in coronavirus disease 2019 (COVID-19).1COVID-19-associated pulmonary aspergillosis (CAPA) appeared more prevalent in the UK’s second wave than the first.2 Plausible explanations include the greater use of immune-modulating drugs, such as dexamethasone,3 anti-IL-therapy4 and improved survival leading to protracted ICU stays.

https://watermark.silverchair.com/d...BOTZTp8GxibuCcchETQdUF8v_yYZxkdwCQXhygzAUxkCH
 
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