Giuseppe
Emeritus
[Source: The Lancet Infectious Diseases, full page: (LINK). Abstract, edited.]
------
The Lancet Infectious Diseases, Early Online Publication, 2 July 2013
doi:10.1016/S1473-3099(13)70136-1
Copyright ? 2013 Elsevier Ltd All rights reserved.
Molecular epidemiology of community-associated meticillin-resistant Staphylococcus aureus in Asia
Original Text
Yu-Yu Chuang MD a, Prof Yhu-Chering Huang MD b c
Summary
In Asia, most reports on the epidemiology of community-associated meticillin-resistant Staphylococcus aureus (CA-MRSA) are from developed countries, with few data from resource-limited countries, not because of low actual prevalence, but probably because of scarce diagnostic facilities. The rate of MRSA in all community-associated S aureus infections in Asian countries ranges from 2?5% to 39%. Unlike the predominance of USA300-sequence type (ST) 8 staphylococcal cassette chromosome mec (SCCmec) type IV in the USA, the molecular epidemiology of CA-MRSA in Asia is characterised by clonal heterogeneity, similar to that in Europe. The emergence of CA-MRSA is a threat in both community and hospital settings because such strains are now more prevalent than are health-care-associated MRSA (HA-MRSA) strains. Many epidemic clones are in circulation in Asia and with scarce data available, concern has arisen that CA-MRSA could have devastating results if it becomes epidemic in resource-poor regions. The epidemiology of CA-MRSA in Asia is closely linked with the health of both developing and developed countries. The present situation of CA-MRSA in Asia is important not only for local public health, but also to provide a better understanding of the successful epidemic clones of this global pathogen.
________
a Department of Pediatrics, St Mary's Hospital, Luodong, Taiwan; b Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Kweishan, Taiwan; c Department of Chinese Medicine, Chang Gung University College of Medicine, Kweishan, Taiwan
Correspondence to: Prof Yhu-Chering Huang, Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Kweishan, Taiwan
-doi:10.1016/S1473-3099(13)70136-1
Copyright ? 2013 Elsevier Ltd All rights reserved.
Molecular epidemiology of community-associated meticillin-resistant Staphylococcus aureus in Asia
Original Text
Yu-Yu Chuang MD a, Prof Yhu-Chering Huang MD b c
Summary
In Asia, most reports on the epidemiology of community-associated meticillin-resistant Staphylococcus aureus (CA-MRSA) are from developed countries, with few data from resource-limited countries, not because of low actual prevalence, but probably because of scarce diagnostic facilities. The rate of MRSA in all community-associated S aureus infections in Asian countries ranges from 2?5% to 39%. Unlike the predominance of USA300-sequence type (ST) 8 staphylococcal cassette chromosome mec (SCCmec) type IV in the USA, the molecular epidemiology of CA-MRSA in Asia is characterised by clonal heterogeneity, similar to that in Europe. The emergence of CA-MRSA is a threat in both community and hospital settings because such strains are now more prevalent than are health-care-associated MRSA (HA-MRSA) strains. Many epidemic clones are in circulation in Asia and with scarce data available, concern has arisen that CA-MRSA could have devastating results if it becomes epidemic in resource-poor regions. The epidemiology of CA-MRSA in Asia is closely linked with the health of both developing and developed countries. The present situation of CA-MRSA in Asia is important not only for local public health, but also to provide a better understanding of the successful epidemic clones of this global pathogen.
________
a Department of Pediatrics, St Mary's Hospital, Luodong, Taiwan; b Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Kweishan, Taiwan; c Department of Chinese Medicine, Chang Gung University College of Medicine, Kweishan, Taiwan
Correspondence to: Prof Yhu-Chering Huang, Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Kweishan, Taiwan
------