tetano
Editor, Senior Moderator
Clin Chim Acta. 2010 Sep 1. [Epub ahead of print]
The influence of influenza A (H1N1) virus on creatinine and cystatin C.
Guo Z, Wang Q, Wu Z, Zhu J, Qiu Y, Zheng L, Qiu L.
Department of Emergency, First People's Hospital of Hangzhou, Hangzhou, Zhejiang Province, People's Republic of China.
Abstract
BACKGROUND: In March 2009, the novel 2009 influenza A (H1N1) virus was first reported in the southwestern USA and Mexico. It rapidly spread to China and worldwide. We investigated possible kidney injury in patients with the 2009 influenza A (H1N1) virus in China.
METHODS: This study was a retrospective cohort investigation of the potential renal injury in patients of influenza. One hundred and seventy-two patients confirmed to have the 2009 influenza A (H1N1) virus but who had different levels of severity (non-severe, severe, critically severe) and 21 cases who were influenza A (H1N1)-negative but who had an influenza-like illness were investigated. Blood samples were obtained for the measurement of creatinine (Cr) and cystatin C (Cy-C).
RESULTS: The influenzaA (H1N1) virus caused more illness in middle-aged people in all groups. The patients in the non-severe group were younger than those in the severe group (p<0.05) and the non-influenza A (H1N1) group (p<0.01). Four subjects in the critically severe group died (3 due to respiratory failure, 1 heart injury). A significant difference in the levels of Cr and Cy-C between the groups was not observed (p>0.05).
CONCLUSION: The 2009 influenza A (H1N1) virus did not cause severe kidney injury in the acute phase in adult patients.
PMID: 20816950 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/20816950
The influence of influenza A (H1N1) virus on creatinine and cystatin C.
Guo Z, Wang Q, Wu Z, Zhu J, Qiu Y, Zheng L, Qiu L.
Department of Emergency, First People's Hospital of Hangzhou, Hangzhou, Zhejiang Province, People's Republic of China.
Abstract
BACKGROUND: In March 2009, the novel 2009 influenza A (H1N1) virus was first reported in the southwestern USA and Mexico. It rapidly spread to China and worldwide. We investigated possible kidney injury in patients with the 2009 influenza A (H1N1) virus in China.
METHODS: This study was a retrospective cohort investigation of the potential renal injury in patients of influenza. One hundred and seventy-two patients confirmed to have the 2009 influenza A (H1N1) virus but who had different levels of severity (non-severe, severe, critically severe) and 21 cases who were influenza A (H1N1)-negative but who had an influenza-like illness were investigated. Blood samples were obtained for the measurement of creatinine (Cr) and cystatin C (Cy-C).
RESULTS: The influenzaA (H1N1) virus caused more illness in middle-aged people in all groups. The patients in the non-severe group were younger than those in the severe group (p<0.05) and the non-influenza A (H1N1) group (p<0.01). Four subjects in the critically severe group died (3 due to respiratory failure, 1 heart injury). A significant difference in the levels of Cr and Cy-C between the groups was not observed (p>0.05).
CONCLUSION: The 2009 influenza A (H1N1) virus did not cause severe kidney injury in the acute phase in adult patients.
PMID: 20816950 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/20816950