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The impact of influenza and respiratory syncytial virus on hospitalizations for lower respiratory tract infections in young children: Slovenia, 2006-2

tetano

Editor, Senior Moderator
Influenza Other Respi Viruses. 2013 Jun 20. doi: 10.1111/irv.12134. [Epub ahead of print]
The impact of influenza and respiratory syncytial virus on hospitalizations for lower respiratory tract infections in young children: Slovenia, 2006-2011.
Učakar V, Sočan M, Trilar KP.
Source

National Institute of Public Health, Ljubljana, Slovenia.
Abstract
BACKGROUND:

Influenza and respiratory syncytial viruses (RSV) are important viral pathogens in childhood.
OBJECTIVES:

Our aim was to estimate the effect of influenza and RSV on excess hospitalizations for acute lower respiratory tract infections (ALRTI) in children aged ≤5.
METHODS:

Retrospective, population-based study was performed for five seasons (2006-2011). Slovenian national hospital discharge data and surveillance data were used to estimate the effect of influenza and/or RSV on ALRTI hospitalizations (acute bronchiolitis, pneumonia, and acute bronchitis) using rate difference method.
RESULTS:

An excess was observed in average weekly ALRTI hospitalizations per 100 000 among children aged ≤5 in all five seasons during influenza and/or RSV active period. During three seasons, there was higher excess in ALRTI hospitalizations in the period when influenza/RSV cocirculated compared with the RSV period. In pandemic season (2009/2010), the only one without influenza/RSV overlap, excess hospitalization was higher in RSV period. The highest excess of hospitalizations was found among the youngest children (0-5 months old). In all five seasons, acute bronchiolitis was the most common ALRTI recorded in hospitalized young children.
CONCLUSIONS:

Respiratory syncytial viruses was leading viral pathogen associated with ALRTI hospitalizations in children aged ≤5. The cocirculation of influenza virus increased the burden of ALRTI hospitalizations especially in seasons with A(H3) predominance.

? 2013 John Wiley & Sons Ltd.

PMID:
23782430
[PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/23782430
 
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