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The H1N1 flu vaccine could protect against the 1918 strain
Posted 06/17/1910 23:00 -
WEDNESDAY, June 16 (HealthDay News / DrTango) - The H1N1 influenza vaccine distributed in 2009 also appears to protect against the Spanish influenza virus that killed more than 50 million people almost a century ago, reveals research in mice.
The findings are derived from work funded by the National Institute of Allergy and Infectious Diseases, USA. UU., Part of the National Institutes of Health, which examined the effectiveness of the vaccine in the protection of influenza in mice.
"Although the reconstruction of the extinct virus of Spanish flu was important to help other pandemic viruses study raises some concerns about an accidental release in the laboratory or its use as an agent of bioterrorism," said study author Adolfo Garc?a-Sastre , professor of microbiology at Mount Sinai School of Medicine, in a press release from the school. "Our research shows that the H1N1 influenza vaccine protects against 2009 Spanish flu virus, an important step in preventing another devastating pandemic like that of 1918."
Garcia-Sastre and colleagues report their findings in the current issue of Nature Communications.
The authors worked with three groups of mice, one would put the flu vaccine H1N, 2009, another vaccine against seasonal influenza and the third none.
Three weeks after vaccination, all mice were exposed to a lethal dose of the Spanish flu virus of 1918. The researchers found that mice only group that had been inoculated with 2009 H1N1 vaccine could survive, although some of that group also succumbed as a result of exposure to the Spanish influenza.
In a second round of testing, Garcia-Sastre team also injected the mice blood serum of people who had been vaccinated against the H1N1 and then exposed to the Spanish flu virus. This time, the researchers found that the antibodies present in human blood exposed to the H1N1 flu vaccine also provided some protection against the Spanish influenza.
"Given the millions of people who have been vaccinated against influenza H1N1, 2009, the cross-protection against influenza virus of 1918 could also be generalized," said Garcia-Sastre. "Our research indicates that people exposed to the virus may also be protected. We hope to conduct more research on the benefits of vaccines against H1N1 2009 virus protection against deadly 1918 Spanish flu."
More
For more information about the flu epidemic of 1918, visit the University of Stanford.
The H1N1 flu vaccine could protect against the 1918 strain
Posted 06/17/1910 23:00 -
WEDNESDAY, June 16 (HealthDay News / DrTango) - The H1N1 influenza vaccine distributed in 2009 also appears to protect against the Spanish influenza virus that killed more than 50 million people almost a century ago, reveals research in mice.
The findings are derived from work funded by the National Institute of Allergy and Infectious Diseases, USA. UU., Part of the National Institutes of Health, which examined the effectiveness of the vaccine in the protection of influenza in mice.
"Although the reconstruction of the extinct virus of Spanish flu was important to help other pandemic viruses study raises some concerns about an accidental release in the laboratory or its use as an agent of bioterrorism," said study author Adolfo Garc?a-Sastre , professor of microbiology at Mount Sinai School of Medicine, in a press release from the school. "Our research shows that the H1N1 influenza vaccine protects against 2009 Spanish flu virus, an important step in preventing another devastating pandemic like that of 1918."
Garcia-Sastre and colleagues report their findings in the current issue of Nature Communications.
The authors worked with three groups of mice, one would put the flu vaccine H1N, 2009, another vaccine against seasonal influenza and the third none.
Three weeks after vaccination, all mice were exposed to a lethal dose of the Spanish flu virus of 1918. The researchers found that mice only group that had been inoculated with 2009 H1N1 vaccine could survive, although some of that group also succumbed as a result of exposure to the Spanish influenza.
In a second round of testing, Garcia-Sastre team also injected the mice blood serum of people who had been vaccinated against the H1N1 and then exposed to the Spanish flu virus. This time, the researchers found that the antibodies present in human blood exposed to the H1N1 flu vaccine also provided some protection against the Spanish influenza.
"Given the millions of people who have been vaccinated against influenza H1N1, 2009, the cross-protection against influenza virus of 1918 could also be generalized," said Garcia-Sastre. "Our research indicates that people exposed to the virus may also be protected. We hope to conduct more research on the benefits of vaccines against H1N1 2009 virus protection against deadly 1918 Spanish flu."
More
For more information about the flu epidemic of 1918, visit the University of Stanford.