The first case of meningitis associated to SARS-Coronavirus-2 BA.2 variant infection with persistent viremia - ISID Journal Preproof

[Mary Wilson]

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Published: September 12, 2022

DOI: https://doi.org/10.1016/j.ijid.2022.09.011

Alessandra D'Abramo, Serena Vita, Francesca Colavita, Eleonora Cimini, Shalom Haggiag, Gaetano Maffongelli, Maria Beatrice Valli, Nazario Bevilacqua, Angela Corpolongo, Maria Letizia Giancola, Fabrizio Maggi, Chiara Agrati, Emanuele Nicastri

Highlights

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  Neurological disorders during COronaVIrus Disease-2019 (COVID-19) are rare
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  Plasmatic viremia could be persistent in immunocompromised patients
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  Immunosuppression and BBB injury could facilitate SARS-COV-2 entry
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  CNS SARS-COV-2 detection should be performed in neurological patients

Abstract

Severe neurological disorders and vascular events during COronaVIrus Disease-2019 (COVID-19) have been described. Here, we describe the first case of a female patient infected with Omicron SARS-CoV-2 BA.2 Variant of Concern (VoC) meningitis with newly diagnosed central demyelinating disease.

https://www.ijidonline.com/action/showPdf?pii=S1201-9712(22)00510-0