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The evolution and molecular characteristics of H9N2 avian influenza viruses in Jiangxi of China

tetano

Editor, Senior Moderator
J Med Virol. 2018 Dec 17. doi: 10.1002/jmv.25363. [Epub ahead of print]
[h=1]The evolution and molecular characteristics of H9N2 avian influenza viruses in Jiangxi of China.[/h] Han L[SUP]1[/SUP], He W[SUP]1[/SUP], Yan H[SUP]1[/SUP], Li X[SUP]1[/SUP], Wang C[SUP]2[/SUP], Shi Q[SUP]3[/SUP], Zhou T[SUP]4[/SUP], Dong G[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] To understand the evolution and molecular characteristics of Jiangxi H9N2 viruses, we isolated 17 viruses in 2011 and analyzed their characteristics. Phylogenetic analyses revealed that their hemagglutinin genes originate from JS/1/00-like sublineage, neuraminidase genes originate from BJ/94-like sublineage, PB1, PA, NP, and NS genes all come from SH/F/98-like sublineage, PB2 genes originate from ST/163/04-like sublineage, while M genes come from G1-like sublineage. Genotype analysis showed that our isolates were classified as genotype 57. Molecular analyses indicated that our strains contained specific sites characteristic of low-pathogenic viruses. The current study once again highlights the necessity for continued surveillance of novel H9N2 viruses.


[h=4]KEYWORDS:[/h] H9N2 influenza virus; genotype analysis; molecular analyses; phylogenetic analyses

PMID: 30560545 DOI: 10.1002/jmv.25363
 
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