tetano
Editor, Senior Moderator
Epidemiol Infect. 2017 Apr 3:1-10. doi: 10.1017/S0950268817000590. [Epub ahead of print]
[h=1]The emergence of enterovirus D68 in England in autumn 2014 and the necessity for reinforcing enterovirus respiratory screening.[/h] Carrion Martin AI[SUP]1[/SUP], Pebody RG[SUP]2[/SUP], Danis K[SUP]1[/SUP], Ellis J[SUP]2[/SUP], Niazi S[SUP]2[/SUP], DE Lusignan S[SUP]3[/SUP], Brown KE[SUP]2[/SUP], Zambon M[SUP]2[/SUP], Allen DJ[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] In autumn 2014, enterovirus D68 (EV-D68) cases presenting with severe respiratory or neurological disease were described in countries worldwide. To describe the epidemiology and virological characteristics of EV-D68 in England, we collected clinical information on laboratory-confirmed EV-D68 cases detected in secondary care (hospitals), between September 2014 and January 2015. In primary care (general practitioners), respiratory swabs collected (September 2013-January 2015) from patients presenting with influenza-like illness were tested for EV-D68. In secondary care 55 EV-D68 cases were detected. Among those, 45 cases had clinical information available and 89% (40/45) presented with severe respiratory symptoms. Detection of EV-D68 among patients in primary care increased from 0.4% (4/1074; 95% CI 0.1-1.0) (September 2013-January 2014) to 0.8% (11/1359; 95% CI 0.4-1.5) (September 2014-January 2015). Characterization of EV-D68 strains circulating in England since 2012 and up to winter 2014/2015 indicated that those strains were genetically similar to those detected in 2014 in USA. We recommend reinforcing enterovirus surveillance through screening respiratory samples of suspected cases.
[h=4]KEYWORDS:[/h] Enterovirus D68; neurologic manifestations; respiratory infections; respiratory samples
PMID: 28367789 DOI: 10.1017/S0950268817000590
[h=1]The emergence of enterovirus D68 in England in autumn 2014 and the necessity for reinforcing enterovirus respiratory screening.[/h] Carrion Martin AI[SUP]1[/SUP], Pebody RG[SUP]2[/SUP], Danis K[SUP]1[/SUP], Ellis J[SUP]2[/SUP], Niazi S[SUP]2[/SUP], DE Lusignan S[SUP]3[/SUP], Brown KE[SUP]2[/SUP], Zambon M[SUP]2[/SUP], Allen DJ[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] In autumn 2014, enterovirus D68 (EV-D68) cases presenting with severe respiratory or neurological disease were described in countries worldwide. To describe the epidemiology and virological characteristics of EV-D68 in England, we collected clinical information on laboratory-confirmed EV-D68 cases detected in secondary care (hospitals), between September 2014 and January 2015. In primary care (general practitioners), respiratory swabs collected (September 2013-January 2015) from patients presenting with influenza-like illness were tested for EV-D68. In secondary care 55 EV-D68 cases were detected. Among those, 45 cases had clinical information available and 89% (40/45) presented with severe respiratory symptoms. Detection of EV-D68 among patients in primary care increased from 0.4% (4/1074; 95% CI 0.1-1.0) (September 2013-January 2014) to 0.8% (11/1359; 95% CI 0.4-1.5) (September 2014-January 2015). Characterization of EV-D68 strains circulating in England since 2012 and up to winter 2014/2015 indicated that those strains were genetically similar to those detected in 2014 in USA. We recommend reinforcing enterovirus surveillance through screening respiratory samples of suspected cases.
[h=4]KEYWORDS:[/h] Enterovirus D68; neurologic manifestations; respiratory infections; respiratory samples
PMID: 28367789 DOI: 10.1017/S0950268817000590