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The clinical characteristics and treatment of community outbreaks of the new influenza A (H1N1) infection

tetano

Editor, Senior Moderator
Zhonghua Jie He He Hu Xi Za Zhi. 2010 Jun;33(6):419-421.
[The clinical characteristics and treatment of community outbreaks of the new influenza A (H1N1) infection.]

[Article in Chinese]

Wang P, Zhu ML, Song HJ, Xiao Q, Kong XC, Peng WH, Xing SL, Guo AM.

Department of Respiratory Medicine, 306th Hospital, Beijing 100101, China. Email: pingwang306@gmail.com.
Abstract

OBJECTIVE: To describe the clinical characteristics of 3 community outbreaks of the novel influenza A (H1N1), and to compare the treatment effects of the traditional Chinese medicine with or without Oseltamivir.

METHOD: The clinical records of 234 patients in 3 community outbreaks of the novel influenza A (H1N1) infection in June (n = 56), August (n = 96) and October (n = 82) of 2009 were analyzed, and the treatment effects of the traditional Chinese medicine with or without Oseltamivir were evaluated.

RESULTS: The baseline characteristics, including age, temperature, indices of blood tests, hepatic and renal functions were distributed evenly between the 2 treatment groups. The overall analysis suggested that there was no significant difference between the 2 treatment groups in the duration of clinical symptoms (P > 0.05), the duration of fever (P > 0.05), and the hospitalization days (P > 0.05). However, an analysis stratified by the temperature (≥ 39?C or < 39?C) suggested that patients treated by the traditional Chinese medicine with Oseltamivir tended to suffer a shorter duration of fever [40.5 (37.3, 42.0) vs 22.0 (10.5, 30.8) hr, P < 0.01) ] in the higher temperature group.

CONCLUSIONS: The traditional Chinese medicine was equivalent to oseltamivir in treating patients with the novel influenza A (H1N1) infection with lower temperature (< 39?C). Oseltamivir was effective in shortening the duration of fever in patients with temperature higher than 39?C.

PMID: 20979812 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/20979812
 
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