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The burden of influenza A and B in Mexico from the year 2010 to 2013: An observational, retrospective, database study, on records from the Directorate

tetano

Editor, Senior Moderator
Hum Vaccin Immunother. 2018 May 10:1-9. doi: 10.1080/21645515.2018.1456281. [Epub ahead of print]
[h=1]The burden of influenza A and B in Mexico from the year 2010 to 2013: An observational, retrospective, database study, on records from the Directorate General of Epidemiology database.[/h] Cortes-Alcala R[SUP]1[/SUP], Dos Santos G[SUP]2[/SUP], DeAntonio R[SUP]3[/SUP], Devadiga R[SUP]4[/SUP], Ruiz-Matus C[SUP]5[/SUP], Jimenez-Corona ME[SUP]6[/SUP], Diaz-Quinonez JA[SUP]7,[/SUP][SUP]8[/SUP], Romano-Mazzotti L[SUP]9[/SUP], Cervantes-Apolinar MY[SUP]10[/SUP], Kuri-Morales P[SUP]8,[/SUP][SUP]11[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] Despite vaccination programs, influenza still represents a significant disease burden in Mexico. We conducted an observational, retrospective analysis to better understand the epidemiological situation of the influenza virus in Mexico. Analysis of the seasonal patterns of influenza A and B were based on the Directorate General of Epidemiology dataset of influenza-like illness(ILI), and severe acute respiratory infection(SARI) that were recorded between January 2010 and December 2013. Our objectives were 1) to describe influenza A and B activity, by age group, and subtype and, 2) to analyze the number of laboratory-confirmed cases presenting with ILI by influenza type, the regional distribution of influenza, and its clinical features. Three periods of influenza activity were captured: August 2010-January 2011, December 2011-March 2012, and October 2012-March 2013. Cases were reported throughout Mexico, with 50.3% (n = 10,320) of cases found in 18-49 year olds. Over the entire capture period, a total of 76,085 ILI/SARI episodes had swab samples analyzed for influenza, 27% were positive. During the same period, influenza A cases were higher in the 18-49 years old, and influenza B cases in both 5-17 and 18-49 age groups. Peak activity occurred in January 2012 (n = 4,159) and December 2012 (n = 348) for influenza A and B respectively. This analysis confirms that influenza is an important respiratory pathogen for children and adults in Mexico despite vaccination recommendations. School-age children and adolescents were more prone to influenza B infection; while younger adults were susceptible to both influenza A and B viruses. Over the seasons, influenza A and B co-circulated.


[h=4]KEYWORDS:[/h] Epidemiology; Influenza A; Influenza B; Influenza vaccine; Mexico, Surveillance

PMID: 29746798 DOI: 10.1080/21645515.2018.1456281
 
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