tetano
Editor, Senior Moderator
Environ Sci Technol. 2019 Nov 22. doi: 10.1021/acs.est.9b04295. [Epub ahead of print] [h=1]The Associations between Source-Specific Particulate Matter and Respiratory Infections in New York State Adults.[/h]
Croft DP, Zhang W, Lin S, Thurston SW, Hopke PK, van Wijngaarden E, Squizzato S, Masiol M, Utell MJ, Rich DQ.
[h=3]Abstract[/h] The response of respiratory infections to source-specific particulate matter (PM) is an area of active research. Using source-specific PM2.5 concentrations at 6 urban sites in New York State, a case-crossover design, and conditional logistic regression, we examined the association between source-specific PM and the rate of hospitalizations and emergency department (ED) visits for influenza or culture negative pneumonia from 2005-2016. There were at most N=14,764 influenza hospitalizations, N=57,522 influenza ED visits, N=274,226 culture negative pneumonia hospitalizations, and N=113,997 culture negative pneumonia ED visits included in our analyses. We separately estimated the rate of respiratory infection associated with increased concentrations of source-specific PM2.5, including secondary sulfate (SS), secondary nitrate (SN), biomass burning (BB), pyrolyzed organic carbon (OP), road dust (RD), residual oil (RO), diesel (DIE), and spark-ignition vehicle emissions (GAS). Increased rates of ED visits for influenza were associated with interquartile range increases in concentrations of GAS (Excess Rate [ER] = 9.2%; 95% CI: 4.3%, 14.3%) and DIE (ER = 3.9%; 95% CI: 1.1%, 6.8%) for lag days 0-3. There were similar associations between BB, SS, OP, and RO, influenza ED visits and hospitalizations, but not culture negative pneumonia hospitalizations or ED visits. Short term increases in PM2.5 from traffic and other combustion sources appear to be a potential risk factor for increased rates of influenza hospitalizations and ED visits.
PMID: 31755707 DOI: 10.1021/acs.est.9b04295
Croft DP, Zhang W, Lin S, Thurston SW, Hopke PK, van Wijngaarden E, Squizzato S, Masiol M, Utell MJ, Rich DQ.
[h=3]Abstract[/h] The response of respiratory infections to source-specific particulate matter (PM) is an area of active research. Using source-specific PM2.5 concentrations at 6 urban sites in New York State, a case-crossover design, and conditional logistic regression, we examined the association between source-specific PM and the rate of hospitalizations and emergency department (ED) visits for influenza or culture negative pneumonia from 2005-2016. There were at most N=14,764 influenza hospitalizations, N=57,522 influenza ED visits, N=274,226 culture negative pneumonia hospitalizations, and N=113,997 culture negative pneumonia ED visits included in our analyses. We separately estimated the rate of respiratory infection associated with increased concentrations of source-specific PM2.5, including secondary sulfate (SS), secondary nitrate (SN), biomass burning (BB), pyrolyzed organic carbon (OP), road dust (RD), residual oil (RO), diesel (DIE), and spark-ignition vehicle emissions (GAS). Increased rates of ED visits for influenza were associated with interquartile range increases in concentrations of GAS (Excess Rate [ER] = 9.2%; 95% CI: 4.3%, 14.3%) and DIE (ER = 3.9%; 95% CI: 1.1%, 6.8%) for lag days 0-3. There were similar associations between BB, SS, OP, and RO, influenza ED visits and hospitalizations, but not culture negative pneumonia hospitalizations or ED visits. Short term increases in PM2.5 from traffic and other combustion sources appear to be a potential risk factor for increased rates of influenza hospitalizations and ED visits.
PMID: 31755707 DOI: 10.1021/acs.est.9b04295