Taiwan CDC Confirms First Case of metallo-β-lactamase Enterobacteriaceae

[Missouriwatcher]

On January 14, 2010, Taiwan CDC confirmed this year?s first case of New Delhi metallo-β-lactamase 1 Enterobacteriaceae infection (NDM-1 Enterobacteriaceae infection). The case is a 56-year-old male with a history of uremia. In October, 2010, he traveled to Jiangxi, China for a kidney transplant. In late October, the case returned to Taiwan and the case sought medical attention at a hospital due to lower abdominal pain. An abdominal MRI showed an accumulation of fluid in the abdominal cavity. On November 5, 2010, he was treated with drainage. The drainage fluid was collected for bacteria culture and identification. The laboratory test results showed that the drainage fluid was culture-positive for carbapenem resistant Klebsiella pneumoniae. Subsequently, the drainage fluid collected on November 17 and the urine samples collected on November 27 and December 21 were all culture-positive for carbapenem resistant Klebsiella pneumoniae. The isolated carbapenem resistant Klebsiella pneumoniae was screened for drug resistant-associated genes by the drug resistance monitoring system in the hospital and the bacteria was highly suspected to carry the NDM-1 gene. On January 10, 2011, the hospital reported the case to the health authority as required by law. As the hospital always implements all relevant infection control measures such as isolation/quarantine when a carbapenem-resistant Enterobacteriaceae case is discovered, the abovementioned case has been receiving medical treatment in a single room since his admission to the hospital. During October to December, 2010, the case was the only case tested culture-positive for carbapenem-resistant Enterobacteriaceae (CRE) in the hospital. Thus far, no evidence has shown nosocomial transmission of the bacteria has occurred in the hospital. In Taiwan, Taiwan CDC, major medical centers and research institutes keep about 1,000 CRE strains in collection and no NDM-1-positive Enterobacteriaceae has been isolated from any of the strains. Therefore, the case is suspected to be an imported case though more information is needed to confirm that...
http://www.cdc.gov.tw/ct.asp?xItem=32177&ctNode=960&mp=5