tetano
Editor, Senior Moderator
Eur J Med Chem. 2012 Oct 25;58C:361-367. doi: 10.1016/j.ejmech.2012.10.030. [Epub ahead of print]
Synthesis of fluorescent ristocetin aglycon derivatives with remarkable antibacterial and antiviral activities.
Sipos A, M?t? G, Rőth E, Borb?s A, Batta G, Bereczki I, K?ki S, J?na I, Ostorh?zi E, Rozgonyi F, Vanderlinden E, Naesens L, Herczegh P.
Source
Department of Pharmaceutical Chemistry, Medical and Health Science Centre, University of Debrecen, Egyetem t?r 1, H-4010 Debrecen, Hungary. Electronic address: sipos.attila@pharm.unideb.hu.
Abstract
Isoindole and benzoisoindole derivatives of ristocetin aglycon have been prepared by reaction with o-phthalaldehyde or naphthalene-2,3-dialdehyde and various thiols. The new compounds exhibited potent antibacterial and anti-influenza virus activity. The cluster forming and fluorescent properties of the aglycon derivatives were also studied.
Copyright ? 2012. Published by Elsevier Masson SAS.
PMID:
23149298
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23149298
Synthesis of fluorescent ristocetin aglycon derivatives with remarkable antibacterial and antiviral activities.
Sipos A, M?t? G, Rőth E, Borb?s A, Batta G, Bereczki I, K?ki S, J?na I, Ostorh?zi E, Rozgonyi F, Vanderlinden E, Naesens L, Herczegh P.
Source
Department of Pharmaceutical Chemistry, Medical and Health Science Centre, University of Debrecen, Egyetem t?r 1, H-4010 Debrecen, Hungary. Electronic address: sipos.attila@pharm.unideb.hu.
Abstract
Isoindole and benzoisoindole derivatives of ristocetin aglycon have been prepared by reaction with o-phthalaldehyde or naphthalene-2,3-dialdehyde and various thiols. The new compounds exhibited potent antibacterial and anti-influenza virus activity. The cluster forming and fluorescent properties of the aglycon derivatives were also studied.
Copyright ? 2012. Published by Elsevier Masson SAS.
PMID:
23149298
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23149298