tetano
Editor, Senior Moderator
Chem Commun (Camb). 2011 Jun 10. [Epub ahead of print]
Synthesis and antiviral activity of highly water-soluble polycarboxylic derivatives of [70]fullerene.
Kornev AB, Peregudov AS, Martynenko VM, Balzarini J, Hoorelbeke B, Troshin PA.
Source
IPCP RAS, Semenov Prospect 1, Chernogolovka, 141432, Russia. troshin2003@inbox.ru.
Abstract
We report here a facile preparation of highly water-soluble derivatives C(70)[p-C(6)H(4)(CH(2))
COOH](8) (n = 2, 3) starting from readily available chlorinated [70]fullerene precursors C(70)Cl(8) and C(70)Cl(10). The synthesized fullerene derivatives showed pronounced antiviral activity in vitro, particularly against human immunodeficiency virus (HIV) and influenza A virus (subtypes H1N1 and H3N2).
PMID:
21666897
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21666897
Synthesis and antiviral activity of highly water-soluble polycarboxylic derivatives of [70]fullerene.
Kornev AB, Peregudov AS, Martynenko VM, Balzarini J, Hoorelbeke B, Troshin PA.
Source
IPCP RAS, Semenov Prospect 1, Chernogolovka, 141432, Russia. troshin2003@inbox.ru.
Abstract
We report here a facile preparation of highly water-soluble derivatives C(70)[p-C(6)H(4)(CH(2))
COOH](8) (n = 2, 3) starting from readily available chlorinated [70]fullerene precursors C(70)Cl(8) and C(70)Cl(10). The synthesized fullerene derivatives showed pronounced antiviral activity in vitro, particularly against human immunodeficiency virus (HIV) and influenza A virus (subtypes H1N1 and H3N2).PMID:
21666897
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21666897