SV40 seroprevalence in two Latin American countries involved in field trials of candidate oral poliovaccines

[Emily]

https://www.sciencedirect.com/science/article/abs/pii/S0163445319301197

SV40 seroprevalence in two Latin American countries involved in field trials of candidate oral poliovaccines
Author: Connie Wong,Shaojie Zhang,Ervin Adam,Lawrence Paszat,Janet S. Butel
Publication: Journal of Infection
Publisher:Elsevier
Date:June 2019
https://doi.org/10.1016/j.jinf.2019.04.007
Highlights


•Polyomavirus SV40 was an unrecognized contaminant of early poliovaccines administered to millions.
•People in Latin America where vaccine trials took place often have SV40 neutralizing antibodies.
•Evidence indicates that SV40 is causing human infections today.
•Results of studies of SV40 infections in humans depend on the populations analyzed.