Laidback Al
Well-known member
Surveillance of H5N1 highly pathogenic avian influenza viruses in wild bird in Surabaya, Indonesia
Djoko E. Poetranto, Masaoki Yamaoka, Fedik Abdul Rantam, Adi.Prijo. Rahardjo, Suwarno Nanik Sianita, Rahayu Ernawati Jola Rahmani, Aldise M. Nastri, Luh AAV. Kxisna, Hanif Rahman, Laksmi Wulandari, Resti Yudhawti, Landia Setiawati, Retno Asih Setyoningrum, Terindah Ermala Ginting, Akiko Makino, Kyoko Shinya, Yoshiro Kawaoka
Waterfowl were originally considered to be natural hosts for influenza A viruses. Consistent with this, H5N1 highly pathogenic avian influenza viruses were reported to be nonpathogenic in wild waterfowl, including ducks (Shortridge et al., 1998). Yet, since 2002, avian H5N1 viruses have been shown to be lethal in wild waterfowl (Chen et al., 2006; Chen et al., 2005: Sturm- Ramirez et al., 2002), suggesting the need to monitor this population. Although H5N1 viruses have spread worldwide among domestic poultry, Indonesia seems to be the hardest hit in terms of H5NI infections. However, the prevalence of H5NI among waterfowl in this country remains unknown.
In 2004 and 2006, the year before and after human victims began to appear in Indonesia (WHO, 2011), we conducted sero-surveillance of H5N1 viruses in wild local waterfowl in Surabaya, Indonesia. During this study, we collected a total of 73 serum samples between May and July 2004. Eleven samples were positive for the hemagglutinin inhibition (HI) test of the H5 subtype. We subsequently collected a total of 30 serum samples from waterfowl between March and May 2006, and found one positive sample by the HI test. In 2007, the year in which reports of human victims were widespread (WHO, 2011), we isolated viruses and carried out hemagglutinin (HA) and HI tests for a total of 113 wild waterfowl samples (85 samples from wild local waterfowl and 28 samples from wild migratory waterfowl) between March and October 2007. There were 16 antibody-positive samples and four samples positive for virus isolation among the 85 local waterfowl samples, and one antibody/virus isolation positive sample among the 28 migratory waterfowl samples.
These samples were obtained along the seashore near Surabaya, Indonesia, at which many local and migratory waterfowl gather. This provides opportunities for local waterfowl to come in contact with both of migratory birds and domestic poultry. Our results underscore the importance of monitoring wild waterfowl and domestic poultry for pandemic preparation in Indonesia.
References
Shortridge, K. F., etal., 1998. Virology-252, 331-342. Chen, H., et al., 2006. J Virol 80, 5976-5983. Chen, H., etal., 2005. Nature 436, 191-192. Sturm-Ramirez, K. M., et al., 2004. J Virol 78,4892-4901.
From: Asian-African Research Forum on Emerging and Reemerging Infections 2012 Date January 11 Wed. to 12 Thu., 2012 Venue Kobe International Conference Center
Conference Schedule and Abstracts - http://www.med.kobe-u.ac.jp/jgrid/sh...ctions2012.pdf
Credits to mixin for pointing out these conference abstracts
Djoko E. Poetranto, Masaoki Yamaoka, Fedik Abdul Rantam, Adi.Prijo. Rahardjo, Suwarno Nanik Sianita, Rahayu Ernawati Jola Rahmani, Aldise M. Nastri, Luh AAV. Kxisna, Hanif Rahman, Laksmi Wulandari, Resti Yudhawti, Landia Setiawati, Retno Asih Setyoningrum, Terindah Ermala Ginting, Akiko Makino, Kyoko Shinya, Yoshiro Kawaoka
Waterfowl were originally considered to be natural hosts for influenza A viruses. Consistent with this, H5N1 highly pathogenic avian influenza viruses were reported to be nonpathogenic in wild waterfowl, including ducks (Shortridge et al., 1998). Yet, since 2002, avian H5N1 viruses have been shown to be lethal in wild waterfowl (Chen et al., 2006; Chen et al., 2005: Sturm- Ramirez et al., 2002), suggesting the need to monitor this population. Although H5N1 viruses have spread worldwide among domestic poultry, Indonesia seems to be the hardest hit in terms of H5NI infections. However, the prevalence of H5NI among waterfowl in this country remains unknown.
In 2004 and 2006, the year before and after human victims began to appear in Indonesia (WHO, 2011), we conducted sero-surveillance of H5N1 viruses in wild local waterfowl in Surabaya, Indonesia. During this study, we collected a total of 73 serum samples between May and July 2004. Eleven samples were positive for the hemagglutinin inhibition (HI) test of the H5 subtype. We subsequently collected a total of 30 serum samples from waterfowl between March and May 2006, and found one positive sample by the HI test. In 2007, the year in which reports of human victims were widespread (WHO, 2011), we isolated viruses and carried out hemagglutinin (HA) and HI tests for a total of 113 wild waterfowl samples (85 samples from wild local waterfowl and 28 samples from wild migratory waterfowl) between March and October 2007. There were 16 antibody-positive samples and four samples positive for virus isolation among the 85 local waterfowl samples, and one antibody/virus isolation positive sample among the 28 migratory waterfowl samples.
These samples were obtained along the seashore near Surabaya, Indonesia, at which many local and migratory waterfowl gather. This provides opportunities for local waterfowl to come in contact with both of migratory birds and domestic poultry. Our results underscore the importance of monitoring wild waterfowl and domestic poultry for pandemic preparation in Indonesia.
References
Shortridge, K. F., etal., 1998. Virology-252, 331-342. Chen, H., et al., 2006. J Virol 80, 5976-5983. Chen, H., etal., 2005. Nature 436, 191-192. Sturm-Ramirez, K. M., et al., 2004. J Virol 78,4892-4901.
From: Asian-African Research Forum on Emerging and Reemerging Infections 2012 Date January 11 Wed. to 12 Thu., 2012 Venue Kobe International Conference Center
Conference Schedule and Abstracts - http://www.med.kobe-u.ac.jp/jgrid/sh...ctions2012.pdf
Credits to mixin for pointing out these conference abstracts