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Surveillance for variant CJD: should more children with neurodegenerative diseases have autopsies?

Emily

Emily

Editor, Senior Moderator
https://adc.bmj.com/content/104/4/360.full;
Verity C, Winstone AM, Will R, et al
Surveillance for variant CJD: should more children with neurodegenerative diseases have autopsies? Archives of Disease in Childhood 2019;104:360-365.

...
  • Since 1997, the PIND Study has identified six UK children with variant Creutzfeldt-Jakob disease (vCJD).
  • In 2017, vCJD was reported in a man who was methionine/valine (MV) heterozygous at PRNP codon 129.
  • This novel finding raises the possibility of a second wave of vCJD cases in UK individuals with the MV genotype....
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