tetano
Editor, Senior Moderator
Surg Infect (Larchmt)
. 2022 Aug 18.
doi: 10.1089/sur.2022.139. Online ahead of print.
COVID-19-Related Intussusception: A Case Series and Review of the Literature
Tyler Leiva[SUP] 1 [/SUP], Christopher Luschen[SUP] 2 [/SUP], Zhongxin Yu[SUP] 3 [/SUP], Heather Liebe[SUP] 1 [/SUP], Alena Golubkova[SUP] 1 [/SUP], Catherine J Hunter[SUP] 1 [/SUP]
Affiliations
Abstract
Background: Ileocolic intussusception is a common gastrointestinal emergency that occurs in infancy. Many cases are caused by anatomic lead points, such as hypertrophied Peyer's patches. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, which causes coronavirus disease 2019 (COVID-19), commonly presents with respiratory symptoms, however, its relation to intussusception remains unknown. Methods: Two cases are reported as well as a review of pertinent English-language literature on the topic. Results: We present two cases of intussusception in COVID-19-positive patients, including the first known case of a lead point with tissue polymerase chain reaction (PCR) confirming COVID-19 positivity, and compare these findings to a review of the recent literature. Intussusception in COVID-19-positive patients is becoming more prevalent and more often requires operative treatment. Discussion: We offer evidence that intussusception can be the presenting symptom in the absence of COVID-19-related respiratory symptoms. There also seems to be a trend toward the need for operative intervention compared with COVID-19-negative intussusception. The presence of SARS-CoV-2 can be confirmed via PCR in specific lead points (lymph nodes), directly causing the intussusception. Conclusions: Providers should have a low threshold to suspect and diagnose intussusception as operative treatment is more readily used in COVID-19-positive pediatric patients with gastrointestinal symptoms.
Keywords: COVID-10; intussusception; laparoscopy; lead point; lymphadenopathy; pathology.
. 2022 Aug 18.
doi: 10.1089/sur.2022.139. Online ahead of print.
COVID-19-Related Intussusception: A Case Series and Review of the Literature
Tyler Leiva[SUP] 1 [/SUP], Christopher Luschen[SUP] 2 [/SUP], Zhongxin Yu[SUP] 3 [/SUP], Heather Liebe[SUP] 1 [/SUP], Alena Golubkova[SUP] 1 [/SUP], Catherine J Hunter[SUP] 1 [/SUP]
Affiliations
- PMID: 35984331
- DOI: 10.1089/sur.2022.139
Abstract
Background: Ileocolic intussusception is a common gastrointestinal emergency that occurs in infancy. Many cases are caused by anatomic lead points, such as hypertrophied Peyer's patches. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, which causes coronavirus disease 2019 (COVID-19), commonly presents with respiratory symptoms, however, its relation to intussusception remains unknown. Methods: Two cases are reported as well as a review of pertinent English-language literature on the topic. Results: We present two cases of intussusception in COVID-19-positive patients, including the first known case of a lead point with tissue polymerase chain reaction (PCR) confirming COVID-19 positivity, and compare these findings to a review of the recent literature. Intussusception in COVID-19-positive patients is becoming more prevalent and more often requires operative treatment. Discussion: We offer evidence that intussusception can be the presenting symptom in the absence of COVID-19-related respiratory symptoms. There also seems to be a trend toward the need for operative intervention compared with COVID-19-negative intussusception. The presence of SARS-CoV-2 can be confirmed via PCR in specific lead points (lymph nodes), directly causing the intussusception. Conclusions: Providers should have a low threshold to suspect and diagnose intussusception as operative treatment is more readily used in COVID-19-positive pediatric patients with gastrointestinal symptoms.
Keywords: COVID-10; intussusception; laparoscopy; lead point; lymphadenopathy; pathology.