AlanBaxter
Member
Has any advice been published on decontamination - chemical (bleach, oxidation, ethanol etc) or physical (UV, detergent etc)?
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Surface sterilisation for 2019-nCov
- Thread starter AlanBaxter
- Start date
sharon sanders
Editor-in-Chief & President
"Use any EPA-registered hospital disinfectant. Follow manufacturer’s recommendations for use-dilution (i.e., concentration), contact time, and care in handling."
https://www.cdc.gov/coronavirus/2019-nCoV/lab/lab-biosafety-guidelines.html
https://www.cdc.gov/coronavirus/2019-nCoV/lab/lab-biosafety-guidelines.html
gsgs
Registered User
https://www.sciencedirect.com/science/article/pii/S0195670105000447
We therefore investigated eight disinfectants for their activity against SARS-CoV
according to prEN 14476. Four hand rubs were tested at 30 s
(Sterillium, based on 45% iso-propanol, 30% n-propanol and 0.2% mecetronium etilsulphate;
Sterillium Rub,based on 80% ethanol;
Sterillium Gel, based on 85% ethanol;
Sterillium Virugard,based on 95% ethanol).
Three surface disinfectants were investigated at 0.5% for 30 min and 60 min
(Mikrobac forte, based on benzalkonium chloride and laurylamine;
Kohrsolin FF, based on benzalkonium chloride, glutaraldehyde and didecyldimonium chloride;
Dismozon pur, based on magnesium monoperphthalate),
and one instrument disinfectant was investigated at 4% for 15 min, 3% for 30 min
and 2% for 60 min
[Korsolex basic, based on glutaraldehyde and (ethylenedioxy)dimethanol].
Three types of organic load were used:
0.3% albumin, 10% fetal calf serum,
and 0.3% albumin with 0.3% sheep erythrocytes.
With all tested preparations, SARS-CoV was inactivated to below the limit of
detection (reduction factor mostly ≥4), regardless of the type of organic load.
In summary, SARS-CoV can be inactivated quite easily with many commonly
used disinfectants.
We therefore investigated eight disinfectants for their activity against SARS-CoV
according to prEN 14476. Four hand rubs were tested at 30 s
(Sterillium, based on 45% iso-propanol, 30% n-propanol and 0.2% mecetronium etilsulphate;
Sterillium Rub,based on 80% ethanol;
Sterillium Gel, based on 85% ethanol;
Sterillium Virugard,based on 95% ethanol).
Three surface disinfectants were investigated at 0.5% for 30 min and 60 min
(Mikrobac forte, based on benzalkonium chloride and laurylamine;
Kohrsolin FF, based on benzalkonium chloride, glutaraldehyde and didecyldimonium chloride;
Dismozon pur, based on magnesium monoperphthalate),
and one instrument disinfectant was investigated at 4% for 15 min, 3% for 30 min
and 2% for 60 min
[Korsolex basic, based on glutaraldehyde and (ethylenedioxy)dimethanol].
Three types of organic load were used:
0.3% albumin, 10% fetal calf serum,
and 0.3% albumin with 0.3% sheep erythrocytes.
With all tested preparations, SARS-CoV was inactivated to below the limit of
detection (reduction factor mostly ≥4), regardless of the type of organic load.
In summary, SARS-CoV can be inactivated quite easily with many commonly
used disinfectants.