tetano
Editor, Senior Moderator
Int J Infect Dis. 2015 Oct 16. pii: S1201-9712(15)00243-X. doi: 10.1016/j.ijid.2015.10.009. [Epub ahead of print]
[h=1]Successful treatment of avian-origin influenza A (H7N9) infection using convalescent plasma.[/h] Wu XX[SUP]1[/SUP], Gao HN[SUP]1[/SUP], Wu HB[SUP]1[/SUP], Peng XM[SUP]1[/SUP], Ou HL[SUP]1[/SUP], Li LJ[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] In January 2015, there was an outbreak of avian-origin influenza A (H7N9) virus in Zhejiang province, China. A 45-year-old man was admitted to the First Affiliated Hospital of Zhejiang University with a high fever that had lasted 7-days, chills, and a cough with yellow sputum. Laboratory testing confirmed infection with the H7N9 virus, likely obtained from contact with poultry at a local live poultry market. A large dense shadow was apparent in the patient's left lung at the time of admission. Treatment with oseltamivir (75mg twice daily) did not improve the patient's condition. The decision was made to try using convalescent plasma to treat the infection. Convalescent plasma was administered three days after the patient was admitted to the hospital and led to marked improvement. To our knowledge, this is the first case to report successfully using convalescent plasma to treat an H7N9 infection in China. Our results suggest that the combination of convalescent plasma and antiviral drugs may be effective for treating avian-origin H7N9 infection.
Copyright ? 2015. Published by Elsevier Ltd.
[h=4]KEYWORDS:[/h] Convalescent plasma; H7N9; Oseltamivir
PMID: 26482389 [PubMed - as supplied by publisher]
[h=1]Successful treatment of avian-origin influenza A (H7N9) infection using convalescent plasma.[/h] Wu XX[SUP]1[/SUP], Gao HN[SUP]1[/SUP], Wu HB[SUP]1[/SUP], Peng XM[SUP]1[/SUP], Ou HL[SUP]1[/SUP], Li LJ[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] In January 2015, there was an outbreak of avian-origin influenza A (H7N9) virus in Zhejiang province, China. A 45-year-old man was admitted to the First Affiliated Hospital of Zhejiang University with a high fever that had lasted 7-days, chills, and a cough with yellow sputum. Laboratory testing confirmed infection with the H7N9 virus, likely obtained from contact with poultry at a local live poultry market. A large dense shadow was apparent in the patient's left lung at the time of admission. Treatment with oseltamivir (75mg twice daily) did not improve the patient's condition. The decision was made to try using convalescent plasma to treat the infection. Convalescent plasma was administered three days after the patient was admitted to the hospital and led to marked improvement. To our knowledge, this is the first case to report successfully using convalescent plasma to treat an H7N9 infection in China. Our results suggest that the combination of convalescent plasma and antiviral drugs may be effective for treating avian-origin H7N9 infection.
Copyright ? 2015. Published by Elsevier Ltd.
[h=4]KEYWORDS:[/h] Convalescent plasma; H7N9; Oseltamivir
PMID: 26482389 [PubMed - as supplied by publisher]