Shiloh
Editor, Senior Moderator
Source: https://wwwnc.cdc.gov/eid/article/24/2/17-1439_article
[h=4]Volume 24, Number 2?February 2018[/h] [h=4]Research[/h] [h=1]Macacine Herpesvirus 1 Antibody Prevalence and DNA Shedding among Invasive Rhesus Macaques, Silver Springs State Park, Florida, USA[/h] Samantha M. Wisely
, Katherine A. Sayler, C. Jane Anderson, Carisa L. Boyce, Amy R. Klegarth, and Steve A. Johnson
Author affiliations: University of Florida, Gainesville, Florida, USA (S.M. Wisely, K.A. Sayler, C.J. Anderson, C.L. Boyce, S.A. Johnson); University of Washington, Seattle, Washington, USA (A.R. Klegarth)
Abstract We compiled records on macacine herpesvirus 1 (McHV-1) seroprevalence and, during 2015?2016, collected saliva and fecal samples from the free-ranging rhesus macaques of Silver Springs State Park, a popular public park in central Florida, USA, to determine viral DNA shedding and perform sequencing. Phylogenetic analysis of the US5 and US5-US6 intragenic sequence from free-ranging and laboratory McHV-1 variants did not reveal genomic differences. In animals captured during 2000?2012, average annual seroprevalence was 25% ? 9 (mean ? SD). We found 4%?14% (95% CI 2%?29%) of macaques passively sampled during the fall 2015 mating season shed McHV-1 DNA orally. We did not observe viral shedding during the spring or summer or from fecal samples. We conclude that these macaques can shed McHV-1, putting humans at risk for exposure to this potentially fatal pathogen. Management plans should be put in place to limit transmission of McHV-1 from these macaques.
[h=4]Volume 24, Number 2?February 2018[/h] [h=4]Research[/h] [h=1]Macacine Herpesvirus 1 Antibody Prevalence and DNA Shedding among Invasive Rhesus Macaques, Silver Springs State Park, Florida, USA[/h] Samantha M. Wisely
, Katherine A. Sayler, C. Jane Anderson, Carisa L. Boyce, Amy R. Klegarth, and Steve A. JohnsonAuthor affiliations: University of Florida, Gainesville, Florida, USA (S.M. Wisely, K.A. Sayler, C.J. Anderson, C.L. Boyce, S.A. Johnson); University of Washington, Seattle, Washington, USA (A.R. Klegarth)
Abstract We compiled records on macacine herpesvirus 1 (McHV-1) seroprevalence and, during 2015?2016, collected saliva and fecal samples from the free-ranging rhesus macaques of Silver Springs State Park, a popular public park in central Florida, USA, to determine viral DNA shedding and perform sequencing. Phylogenetic analysis of the US5 and US5-US6 intragenic sequence from free-ranging and laboratory McHV-1 variants did not reveal genomic differences. In animals captured during 2000?2012, average annual seroprevalence was 25% ? 9 (mean ? SD). We found 4%?14% (95% CI 2%?29%) of macaques passively sampled during the fall 2015 mating season shed McHV-1 DNA orally. We did not observe viral shedding during the spring or summer or from fecal samples. We conclude that these macaques can shed McHV-1, putting humans at risk for exposure to this potentially fatal pathogen. Management plans should be put in place to limit transmission of McHV-1 from these macaques.