tetano
Editor, Senior Moderator
PLoS One. 2015 Oct 1;10(10):e0139431. doi: 10.1371/journal.pone.0139431. eCollection 2015.
[h=1]Striking Similarities in the Presentation and Duration of Illness of Influenza A and B in the Community: A Study Based on Sentinel Surveillance Networks in France and Turkey, 2010-2012.[/h] Cohen JM[SUP]1[/SUP], Silva ML[SUP]2[/SUP], Caini S[SUP]2[/SUP], Ciblak M[SUP]3[/SUP], Mosnier A[SUP]1[/SUP], Daviaud I[SUP]2[/SUP], Matias G[SUP]4[/SUP], Badur S[SUP]3[/SUP], Valette M[SUP]5[/SUP], Enouf V[SUP]6[/SUP], Paget J[SUP]7[/SUP], Fleming DM[SUP]8[/SUP]; IBGP study team.
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza B represents a high proportion of influenza cases in some seasons (even over 50%). The Influenza B study in General Practice (IBGP) is a multicenter study providing information about the clinical, demographic and socio-economic characteristics of patients affected by lab-confirmed influenza A or B. Influenza B patients and age-matched influenza A patients were recruited within the sentinel surveillance networks of France and Turkey in 2010-11 and 2011-12 seasons. Data were collected for each patient at the swab test day, after 9?2 days and, if not recovered, after 28?5 days. It was related to patient's characteristics, symptoms at presentation, vaccination status, prescriptions of antibiotics and antivirals, duration of illness, follow-up consultations in general practice or emergency room. We performed descriptive analyses and developed a multiple regression model to investigate the effect of patients and disease characteristics on the duration of illness. Overall, 774 influenza cases were included in the study: 419 influenza B cases (209 in France and 210 in Turkey) and 355 influenza A cases (205 in France and 150 in Turkey). There were no differences between influenza A and B patients in terms of clinical presentation and number of consultations with a practitioner; however, the use of antivirals was higher among influenza B patients in both countries. The average (median) reported duration of illness in the age groups 0-14 years, 15-64 years and 65+ years was 7.4 (6), 8.7 (8) and 10.5 (9) days in France, and 6.3 (6), 8.2 (7) and 9.2 (6) days in Turkey; it increased with age but did not differ by virus type; increased duration of illness was associated with antibiotics prescription. In conclusion, our findings show that influenza B infection appears not to be milder disease than influenza A infection.
PMID: 26426119 [PubMed - in process]
[h=1]Striking Similarities in the Presentation and Duration of Illness of Influenza A and B in the Community: A Study Based on Sentinel Surveillance Networks in France and Turkey, 2010-2012.[/h] Cohen JM[SUP]1[/SUP], Silva ML[SUP]2[/SUP], Caini S[SUP]2[/SUP], Ciblak M[SUP]3[/SUP], Mosnier A[SUP]1[/SUP], Daviaud I[SUP]2[/SUP], Matias G[SUP]4[/SUP], Badur S[SUP]3[/SUP], Valette M[SUP]5[/SUP], Enouf V[SUP]6[/SUP], Paget J[SUP]7[/SUP], Fleming DM[SUP]8[/SUP]; IBGP study team.
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza B represents a high proportion of influenza cases in some seasons (even over 50%). The Influenza B study in General Practice (IBGP) is a multicenter study providing information about the clinical, demographic and socio-economic characteristics of patients affected by lab-confirmed influenza A or B. Influenza B patients and age-matched influenza A patients were recruited within the sentinel surveillance networks of France and Turkey in 2010-11 and 2011-12 seasons. Data were collected for each patient at the swab test day, after 9?2 days and, if not recovered, after 28?5 days. It was related to patient's characteristics, symptoms at presentation, vaccination status, prescriptions of antibiotics and antivirals, duration of illness, follow-up consultations in general practice or emergency room. We performed descriptive analyses and developed a multiple regression model to investigate the effect of patients and disease characteristics on the duration of illness. Overall, 774 influenza cases were included in the study: 419 influenza B cases (209 in France and 210 in Turkey) and 355 influenza A cases (205 in France and 150 in Turkey). There were no differences between influenza A and B patients in terms of clinical presentation and number of consultations with a practitioner; however, the use of antivirals was higher among influenza B patients in both countries. The average (median) reported duration of illness in the age groups 0-14 years, 15-64 years and 65+ years was 7.4 (6), 8.7 (8) and 10.5 (9) days in France, and 6.3 (6), 8.2 (7) and 9.2 (6) days in Turkey; it increased with age but did not differ by virus type; increased duration of illness was associated with antibiotics prescription. In conclusion, our findings show that influenza B infection appears not to be milder disease than influenza A infection.
PMID: 26426119 [PubMed - in process]