tetano
Editor, Senior Moderator
Stem Cell Res
. 2021 Jan 12;51:102168.
doi: 10.1016/j.scr.2021.102168. Online ahead of print.
The effects of novel coronavirus (SARS-CoV-2) infection on cardiovascular diseases and cardiopulmonary injuries
Ni Li[SUP] 1 [/SUP], Linwen Zhu[SUP] 2 [/SUP], Lebo Sun[SUP] 2 [/SUP], Guofeng Shao[SUP] 3 [/SUP]
Affiliations
Abstract
COVID-19 caused by a novel coronavirus named SARS-CoV-2, can elites severe acute respiratory syndrome, severe lung injury, cardiac injury, and even death and became a worldwide pandemic. SARS-CoV-2 infection may result in cardiac injury via several mechanisms, including the expression of angiotensin-converting enzyme 2 (ACE2) receptor and leading to a cytokine storm, can elicit an exaggerated host immune response. This response contributes to multi-organ dysfunction. As an emerging infectious disease, there are limited data on the effects of this infection on patients with underlying cardiovascular comorbidities. In this review, we summarize the early-stage clinical experiences with COVID-19, with particular focus on patients with cardiovascular diseases and cardiopulmonary injuries, and explores potential available evidence regarding the association between COVID-19, and cardiovascular complications.
Keywords: Cardiopulmonary diseases; Mechanism; SARS-CoV-2.
. 2021 Jan 12;51:102168.
doi: 10.1016/j.scr.2021.102168. Online ahead of print.
The effects of novel coronavirus (SARS-CoV-2) infection on cardiovascular diseases and cardiopulmonary injuries
Ni Li[SUP] 1 [/SUP], Linwen Zhu[SUP] 2 [/SUP], Lebo Sun[SUP] 2 [/SUP], Guofeng Shao[SUP] 3 [/SUP]
Affiliations
- PMID: 33485182
- PMCID: PMC7801189
- DOI: 10.1016/j.scr.2021.102168
Abstract
COVID-19 caused by a novel coronavirus named SARS-CoV-2, can elites severe acute respiratory syndrome, severe lung injury, cardiac injury, and even death and became a worldwide pandemic. SARS-CoV-2 infection may result in cardiac injury via several mechanisms, including the expression of angiotensin-converting enzyme 2 (ACE2) receptor and leading to a cytokine storm, can elicit an exaggerated host immune response. This response contributes to multi-organ dysfunction. As an emerging infectious disease, there are limited data on the effects of this infection on patients with underlying cardiovascular comorbidities. In this review, we summarize the early-stage clinical experiences with COVID-19, with particular focus on patients with cardiovascular diseases and cardiopulmonary injuries, and explores potential available evidence regarding the association between COVID-19, and cardiovascular complications.
Keywords: Cardiopulmonary diseases; Mechanism; SARS-CoV-2.