tetano
Editor, Senior Moderator
SN Compr Clin Med
. 2021 Mar 8;1-8.
doi: 10.1007/s42399-021-00851-1. Online ahead of print.
Diabetes Mellitus and Hypertension Increase Risk of Death in Novel Corona Virus Patients Irrespective of Age: a Prospective Observational Study of Co-morbidities and COVID-19 from India
Anirban Gupta[SUP] 1 [/SUP], Neelabh Nayan[SUP] 1 [/SUP], Ranjith Nair[SUP] 1 [/SUP], Krishna Kumar[SUP] 2 [/SUP], Aditya Joshi[SUP] 2 [/SUP], Shivangi Sharma[SUP] 1 [/SUP], Jasdeep Singh[SUP] 3 [/SUP], Rajan Kapoor[SUP] 1 [/SUP]
Affiliations
Abstract
Elderly people and people with co-morbidities have emerged as the most vulnerable group at risk of developing complications and succumbing to novel coronavirus (COVID-19) infection. We recorded the baseline demographic profile, baseline clinical and laboratory parameters, and prevalence of various co-morbidities and their effect on the prognosis of COVID-19 cases. We conducted a prospective observational study and analyzed baseline clinical and laboratory parameters and co-morbidities and their effect on severity and mortality in 710 COVID-19 cases. Seven hundred ten patients with laboratory-confirmed COVID-19 were recruited from the 28[SUP]th[/SUP] of March to the 31[SUP]st[/SUP] of August 2020. The mean age was 48.4 ? 16.4years. A total of 530 (74.6%) patients were male. Overall, the mean length of hospital stay was 12.7 days. In total, 645 patients(90.8%) were mild to moderate cases and did not require initial ICU care. Sixty-five (9.2%) cases required initial intensive care unit care. Fifty (7%) admitted patients succumbed to the illness. Diabetes mellitus and hypertension increased the risk of death in COVID-19 patients irrespective of age. Increasing age and co-morbidities adversely affect the prognosis of patients of COVID-19. Diabetes mellitus and hypertension increase the risk of death in COVID-19 patients and negate the incremental effect of age on death in these patients.
Keywords: COVID-19; Co-morbidities; Diabetes; Hypertension; Mortality; Prognosis.
. 2021 Mar 8;1-8.
doi: 10.1007/s42399-021-00851-1. Online ahead of print.
Diabetes Mellitus and Hypertension Increase Risk of Death in Novel Corona Virus Patients Irrespective of Age: a Prospective Observational Study of Co-morbidities and COVID-19 from India
Anirban Gupta[SUP] 1 [/SUP], Neelabh Nayan[SUP] 1 [/SUP], Ranjith Nair[SUP] 1 [/SUP], Krishna Kumar[SUP] 2 [/SUP], Aditya Joshi[SUP] 2 [/SUP], Shivangi Sharma[SUP] 1 [/SUP], Jasdeep Singh[SUP] 3 [/SUP], Rajan Kapoor[SUP] 1 [/SUP]
Affiliations
- PMID: 33718779
- PMCID: PMC7939447
- DOI: 10.1007/s42399-021-00851-1
Abstract
Elderly people and people with co-morbidities have emerged as the most vulnerable group at risk of developing complications and succumbing to novel coronavirus (COVID-19) infection. We recorded the baseline demographic profile, baseline clinical and laboratory parameters, and prevalence of various co-morbidities and their effect on the prognosis of COVID-19 cases. We conducted a prospective observational study and analyzed baseline clinical and laboratory parameters and co-morbidities and their effect on severity and mortality in 710 COVID-19 cases. Seven hundred ten patients with laboratory-confirmed COVID-19 were recruited from the 28[SUP]th[/SUP] of March to the 31[SUP]st[/SUP] of August 2020. The mean age was 48.4 ? 16.4years. A total of 530 (74.6%) patients were male. Overall, the mean length of hospital stay was 12.7 days. In total, 645 patients(90.8%) were mild to moderate cases and did not require initial ICU care. Sixty-five (9.2%) cases required initial intensive care unit care. Fifty (7%) admitted patients succumbed to the illness. Diabetes mellitus and hypertension increased the risk of death in COVID-19 patients irrespective of age. Increasing age and co-morbidities adversely affect the prognosis of patients of COVID-19. Diabetes mellitus and hypertension increase the risk of death in COVID-19 patients and negate the incremental effect of age on death in these patients.
Keywords: COVID-19; Co-morbidities; Diabetes; Hypertension; Mortality; Prognosis.