tetano
Editor, Senior Moderator
Emerg Infect Dis. 2011 Apr;17(4):639-44.
Shedding of Pandemic (H1N1) 2009 Virus among Health Care Personnel, Seattle, Washington, USA.
Kay M, Zerr DM, Englund JA, Cadwell BL, Kuypers J, Swenson P, Kwan-Gett TS, Bell SL, Duchin JS.
Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M. Kay, B.L. Cadwell); Public Health-Seattle and King County, Seattle, Washington, USA (M. Kay, P. Swenson, T.S. Kwan-Gett, J.S. Duchin); Seattle Children's Hospital, Seattle (D.M. Zerr, J.A. Englund, S.L. Bell); and University of Washington, Seattle (J. Kuypers, T.S. Kwan-Gett, J.S. Duchin).
Abstract
The Centers for Disease Control and Prevention (CDC) recommends that health care personnel (HCP) infected with pandemic influenza (H1N1) 2009 virus not work until 24 hours after fever subsides without the use of antipyretics. During an influenza outbreak, we examined the association between viral shedding and fever among infected HCP. Participants recorded temperatures daily and provided nasal wash specimens for 2 weeks after symptom onset. Specimens were tested by using PCR and culture. When they met CDC criteria for returning to work, 12 of 16 HCP (75%) (95% confidence interval 48%-93%) had virus detected by PCR, and 9 (56%) (95% confidence interval 30%-80%) had virus detected by culture. Fever was not associated with shedding duration (p = 0.65). HCP might shed virus even when meeting CDC exclusion guidelines. Further research is needed to clarify the association between viral shedding, symptoms, and infectiousness.
PMID: 21470453 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/21470453
Shedding of Pandemic (H1N1) 2009 Virus among Health Care Personnel, Seattle, Washington, USA.
Kay M, Zerr DM, Englund JA, Cadwell BL, Kuypers J, Swenson P, Kwan-Gett TS, Bell SL, Duchin JS.
Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M. Kay, B.L. Cadwell); Public Health-Seattle and King County, Seattle, Washington, USA (M. Kay, P. Swenson, T.S. Kwan-Gett, J.S. Duchin); Seattle Children's Hospital, Seattle (D.M. Zerr, J.A. Englund, S.L. Bell); and University of Washington, Seattle (J. Kuypers, T.S. Kwan-Gett, J.S. Duchin).
Abstract
The Centers for Disease Control and Prevention (CDC) recommends that health care personnel (HCP) infected with pandemic influenza (H1N1) 2009 virus not work until 24 hours after fever subsides without the use of antipyretics. During an influenza outbreak, we examined the association between viral shedding and fever among infected HCP. Participants recorded temperatures daily and provided nasal wash specimens for 2 weeks after symptom onset. Specimens were tested by using PCR and culture. When they met CDC criteria for returning to work, 12 of 16 HCP (75%) (95% confidence interval 48%-93%) had virus detected by PCR, and 9 (56%) (95% confidence interval 30%-80%) had virus detected by culture. Fever was not associated with shedding duration (p = 0.65). HCP might shed virus even when meeting CDC exclusion guidelines. Further research is needed to clarify the association between viral shedding, symptoms, and infectiousness.
PMID: 21470453 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/21470453