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Serological survys on anti-H1N1 IgG of blood donors in Dongguan

tetano

Editor, Senior Moderator
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2012 Aug;26(4):263-5.
[Serological survys on anti-H1N1 IgG of blood donors in Dongguan].
[Article in Chinese]
Wang DW, Liu FP, Liang B.
Source

Central Blood Station of City, 523930 Guangdong, China. wdwn163@163.com
Abstract
OBJECTIVE:

To access the sustained immune effect in influenza A H1N1 vaccine vaccinated-blood donors as well as the level of anti-H1N1 IgG in unvaccinated-blood donors in order to provide reference for preventing and treating influenza A H1N1.
METHODS:

Anti-H1N1 IgG was detected in 1166 vaccinated-blood donors as well as 1265 unvaccinated-blood donors by ELISA method in Dongguan from January 2010 to June 2010.
RESULTS:

The mean positive rate and high-titer rate of anti-H1N1 IgG were 78.82% and 46.57% respectively, both of which were sustained at relatively high level after reaching their peak at vaccination time of 71-90 d. The mean positive rate of anti-H1N1 IgG in unvaccinated-blood donors was 26.01%. No difference was found in the positive rate of anti-H1N1 IgG among different gender or age groups (P > 0.05).
CONCLUSION:

The influenza A H1N1 vaccine, with good sustained immune effect, plays an important role in preventing and treating influenza A H1N1. The positive rate of anti-H1N1 IgG in influenza A HIN1 vaccine unvaccinated-blood donors is low. Vaccination should be strengthened.

PMID:
23189839
[PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/23189839
 
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