tetano
Editor, Senior Moderator
Vet Microbiol. 2015 Jan 2. pii: S0378-1135(14)00595-1. doi: 10.1016/j.vetmic.2014.12.022. [Epub ahead of print]
[h=1]Serological evidence of pandemic (H1N1) 2009 virus in pigs, West and Central Africa.[/h] Snoeck CJ[SUP]1[/SUP], Abiola OJ[SUP]2[/SUP], Sausy A[SUP]1[/SUP], Okwen MP[SUP]3[/SUP], Olubayo AG[SUP]2[/SUP], Owoade AA[SUP]2[/SUP], Muller CP[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Besides birds, pigs are another important reservoir of influenza A viruses that can be transmitted to human, as highlighted by the emergence and spread of the pandemic (H1N1) virus (pdm/09) in 2009. Surveillance in pigs is therefore necessary for public health and influenza pandemic preparedness. Nevertheless, there is a serious lack of data on influenza in Africa, especially in swine. We therefore collected serum samples from pigs in Nigeria (2009, 2012) and Cameroon (2011) in which the presence of anti-influenza A neutralizing antibodies was investigated. Our serological survey suggests that, before the 2009 pandemic, only rare swine and human H3N2 or human H1N1 infections occurred in Nigeria in swine. However, in 2011-2012, 27.4% of pigs in Nigeria and 5.6% in Cameroon had antibodies against H1N1 viruses. Higher antibody titres against pdm/09 suggested that pigs were exposed to this or a similar virus, either by multiple introductions or sustained circulation, and that reactivity against American and European swine H1N1 viruses resulted from cross-reaction.
Copyright ? 2014 Elsevier B.V. All rights reserved.
[h=4]KEYWORDS:[/h] Africa; Influenza A; Neutralizing antibodies; Pandemic virus; Swine
PMID: 25631252 [PubMed - as supplied by publisher]
[h=1]Serological evidence of pandemic (H1N1) 2009 virus in pigs, West and Central Africa.[/h] Snoeck CJ[SUP]1[/SUP], Abiola OJ[SUP]2[/SUP], Sausy A[SUP]1[/SUP], Okwen MP[SUP]3[/SUP], Olubayo AG[SUP]2[/SUP], Owoade AA[SUP]2[/SUP], Muller CP[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Besides birds, pigs are another important reservoir of influenza A viruses that can be transmitted to human, as highlighted by the emergence and spread of the pandemic (H1N1) virus (pdm/09) in 2009. Surveillance in pigs is therefore necessary for public health and influenza pandemic preparedness. Nevertheless, there is a serious lack of data on influenza in Africa, especially in swine. We therefore collected serum samples from pigs in Nigeria (2009, 2012) and Cameroon (2011) in which the presence of anti-influenza A neutralizing antibodies was investigated. Our serological survey suggests that, before the 2009 pandemic, only rare swine and human H3N2 or human H1N1 infections occurred in Nigeria in swine. However, in 2011-2012, 27.4% of pigs in Nigeria and 5.6% in Cameroon had antibodies against H1N1 viruses. Higher antibody titres against pdm/09 suggested that pigs were exposed to this or a similar virus, either by multiple introductions or sustained circulation, and that reactivity against American and European swine H1N1 viruses resulted from cross-reaction.
Copyright ? 2014 Elsevier B.V. All rights reserved.
[h=4]KEYWORDS:[/h] Africa; Influenza A; Neutralizing antibodies; Pandemic virus; Swine
PMID: 25631252 [PubMed - as supplied by publisher]