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Serologic survey on pandemic influenza A (H1N1) virus among aged ≥ 3 years population from Jiangsu province in 2009, China.

tetano

Editor, Senior Moderator
Zhonghua Liu Xing Bing Xue Za Zhi. 2010 May;31(5):489-493.
[Serologic survey on pandemic influenza A (H1N1) virus among aged ≥ 3 years population from Jiangsu province in 2009, China.]

[Article in Chinese]

Tang FY, Zu RQ, Li L, Qi X, Ji H, Wu B, Xu K, Fu JG, Qin YF, Deng F, Yang HT.

Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
Abstract

OBJECTIVE: To understand the antibody levels against pandemic influenza A (H1N1) virus (2009 H1N1) among aged ≥ 3 years population in 2009, from Jiangsu province, and to describe the distribution of 2009 H1N1.

METHODS: Serum specimens were collected from natural populations at four different periods in Jiangsu, and tested with hemagglutination-inhibition (HI) assays. Rates of protective antibody against 2009 H1N1 and Geometric mean titers (GMTs) were estimated.

RESULTS: The rates of protective antibody against 2009 H1N1 rose with the progress of epidemics in Jiangsu, which were 3.46%, 7.59%, 16.94%, respectively in July, August and November, 2009. There were no significant differences on the rates of protective antibody between males and females at four different cross-sectional periods (P > 0.05), and no significant differences on GMTs were observed at different periods except for November 2009. Significant differences on rates of protective antibody and GMTs among various age groups were observed at four different periods (P < 0.05), and similar results were observed among different periods in various age groups (P < 0.05). There were significant differences on rates of protective antibody and GMTs among different areas (P < 0.05).

CONCLUSION: The 2009 H1N1 strain had been widely spread out in Jiangsu province since July 2009. People aged 12 - 17 years became the major victims after August. As of November 2009, the rate of protective antibody against 2009 H1N1 was still low, predicting that the epidemic might continue to exist for a certain period of time.

PMID: 21163021 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/21163021
 
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