Seroincidence of Influenza Among HIV-infected and HIV-uninfected Men During the 2009 H1N1 Influenza Pandemic, Bangkok, Thailand

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Open Forum Infect Dis. 2014 Oct 10;1(3)fu082. doi: 10.1093/ofid/ofu082. eCollection 2014.
[h=1]Seroincidence of Influenza Among HIV-infected and HIV-uninfected Men During the 2009 H1N1 Influenza Pandemic, Bangkok, Thailand.[/h] Garg S[SUP]1[/SUP], Olsen SJ[SUP]2[/SUP], Fernandez S[SUP]3[/SUP], Muangchana C[SUP]4[/SUP], Rungrojcharoenkit K[SUP]3[/SUP], Prapasiri P[SUP]5[/SUP], Katz JM[SUP]6[/SUP], Curlin ME[SUP]7[/SUP], Gibbons RV[SUP]3[/SUP], Holtz TH[SUP]7[/SUP], Chitwarakorn A[SUP]8[/SUP], Dawood FS[SUP]6[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] Among 368 Thai men who have sex with men with paired serum samples collected before and during the 2009 H1N1 influenza pandemic, we determined influenza A (H1N1)pdm09 seroconversion rates (≥4-fold rise in antibody titers by hemagglutination inhibition or microneutralization assays). Overall, 66 of 232 (28%) participants seroconverted after the first year of A(H1N1)pdm09 activity, and 83 of 234 (35%) participants seroconverted after the second year. Influenza A(H1N1)pdm09 seroconversion did not differ between human immunodeficiency virus (HIV)-infected (55 of 2157 [35%]) and HIV-uninfected (71 of 2211 [34%]) participants (P = .78). Influenza A(H1N1)pdm09 seroconversion occurred in approximately one third of our Thai study population and was similar among HIV-infected and HIV-uninfected participants.


[h=4]KEYWORDS:[/h] A(H1N1)pdm09; HIV; Thailand; influenza; pandemic; serology

PMID: 25734157 [PubMed] PMCID: PMC4324228 Free PMC Article