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Scientists identify 16 new genetic variants associated with severe Covid-19
The findings includedhow a single gene variant was enough to increase a patient’s risk of severe disease
Simon Rushton
Mar 08, 2022
Sixteen new genetic variants associated with severe Covid-19 have been identified by scientists taking part in the world’s biggest coronavirus gene study.
Patients can require extended hospital stays, with complications including blood clots, immune response and inflammation, and the study offers hopes for new treatments.
Researchers identified DNA differences that may explain why some people get more severely ill from coronavirus, and they also now know more about the virus than other conditions routinely seen in hospitals, such as sepsis and flu.
The GenOMICC consortium, a global collaboration led by University of Edinburgh, is the world's largest study of the genes involved in critical Covid-19 and included more than 57,000 people.
Sir Mark Caulfield, from Queen Mary University of London, said: "I think what we can say today is that these variants do denote people that are more likely to have a critical illness.
"And if we knew about them earlier in the course of their illness, we might be able to consider early intervention with some of the medicines we've been talking about, such as dexamethasone or others to try and prevent an adverse outcome."...
Scientists identify 16 new genetic variants associated with severe Covid-19
The findings includedhow a single gene variant was enough to increase a patient’s risk of severe disease
Simon Rushton
Mar 08, 2022
Sixteen new genetic variants associated with severe Covid-19 have been identified by scientists taking part in the world’s biggest coronavirus gene study.
Patients can require extended hospital stays, with complications including blood clots, immune response and inflammation, and the study offers hopes for new treatments.
Researchers identified DNA differences that may explain why some people get more severely ill from coronavirus, and they also now know more about the virus than other conditions routinely seen in hospitals, such as sepsis and flu.
The GenOMICC consortium, a global collaboration led by University of Edinburgh, is the world's largest study of the genes involved in critical Covid-19 and included more than 57,000 people.
Sir Mark Caulfield, from Queen Mary University of London, said: "I think what we can say today is that these variants do denote people that are more likely to have a critical illness.
"And if we knew about them earlier in the course of their illness, we might be able to consider early intervention with some of the medicines we've been talking about, such as dexamethasone or others to try and prevent an adverse outcome."...
