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Science: Zika virus impairs growth in human neurospheres and brain organoids

sharon sanders

Editor-in-Chief & President
[h=1][/h] Zika virus impairs growth in human neurospheres and brain organoids

  • Patricia P. Garcez1,2,*,
  • Erick Correia Loiola2,?,
  • Rodrigo Madeiro da Costa2,?,
  • Luiza M. Higa3,?,
  • Pablo Trindade2,?,
  • Rodrigo Delvecchio3,
  • Juliana Minardi Nascimento2,4,
  • Rodrigo Brindeiro3,
  • Amilcar Tanuri3,
  • Stevens K. Rehen2,1,*





Cell death impairing brain enlargement, calcification and microcephaly is well described in congenital infections with TORCHS (3, 23, 24). Our results, together with recent reports showing brain calcification in microcephalic fetuses and newborns infected with ZIKV (10, 14) reinforce the growing body of evidence connecting congenital ZIKV outbreak to the increased number of reports of brain malformations in Brazil.

http://science.sciencemag.org/content/early/2016/04/08/science.aaf6116.full


hat tip Michael Coston and tetano for the link
 
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