tetano
Editor, Senior Moderator
Science
. 2022 May 24;eabq4411.
doi: 10.1126/science.abq4411. Online ahead of print.
Twin peaks: The Omicron SARS-CoV-2 BA.1 and BA.2 epidemics in England
Paul Elliott[SUP] 1 2 3 4 5 6 [/SUP], Oliver Eales[SUP] #[/SUP][SUP] 1 7 [/SUP], Nicholas Steyn[SUP] #[/SUP][SUP] 8 9 [/SUP], David Tang[SUP] #[/SUP][SUP] 1 2 [/SUP], Barbara Bodinier[SUP] 1 2 [/SUP], Haowei Wang[SUP] 1 7 [/SUP], Joshua Elliott[SUP] 3 10 [/SUP], Matthew Whitaker[SUP] 1 2 [/SUP], Christina Atchison[SUP] 1 3 [/SUP], Peter J Diggle[SUP] 11 [/SUP], Andrew J Page[SUP] 12 [/SUP], Alexander J Trotter[SUP] 12 [/SUP], Deborah Ashby[SUP] 1 [/SUP], Wendy Barclay[SUP] 10 [/SUP], Graham Taylor[SUP] 10 [/SUP], Helen Ward[SUP] 1 3 4 7 [/SUP], Ara Darzi[SUP] 3 4 13 [/SUP], Graham S Cooke[SUP] 3 4 10 [/SUP], Christl A Donnelly[SUP] #[/SUP][SUP] 1 7 8 [/SUP], Marc Chadeau-Hyam[SUP] #[/SUP][SUP] 1 2 [/SUP]
Affiliations
Abstract
Rapid transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has led to record-breaking incidence rates around the world. The REal-time Assessment of Community Transmission-1 (REACT-1) study has tracked SARS-CoV-2 infection in England using reverse transcription polymerase chain reaction (RT-PCR) results from self-administered throat and nose swabs from randomly selected participants aged 5+ years, approximately monthly from May 2020 to March 2022. Weighted prevalence in March 2022 was the highest recorded in REACT-1 at 6.37% (N=109,181) with Omicron BA.2 largely replacing BA.1. Prevalence was increasing overall with the greatest increase in those aged 65-74 and 75+ years. This was associated with increased hospitalizations and deaths but at much lower levels than in previous waves against a backdrop of high levels of vaccination.
. 2022 May 24;eabq4411.
doi: 10.1126/science.abq4411. Online ahead of print.
Twin peaks: The Omicron SARS-CoV-2 BA.1 and BA.2 epidemics in England
Paul Elliott[SUP] 1 2 3 4 5 6 [/SUP], Oliver Eales[SUP] #[/SUP][SUP] 1 7 [/SUP], Nicholas Steyn[SUP] #[/SUP][SUP] 8 9 [/SUP], David Tang[SUP] #[/SUP][SUP] 1 2 [/SUP], Barbara Bodinier[SUP] 1 2 [/SUP], Haowei Wang[SUP] 1 7 [/SUP], Joshua Elliott[SUP] 3 10 [/SUP], Matthew Whitaker[SUP] 1 2 [/SUP], Christina Atchison[SUP] 1 3 [/SUP], Peter J Diggle[SUP] 11 [/SUP], Andrew J Page[SUP] 12 [/SUP], Alexander J Trotter[SUP] 12 [/SUP], Deborah Ashby[SUP] 1 [/SUP], Wendy Barclay[SUP] 10 [/SUP], Graham Taylor[SUP] 10 [/SUP], Helen Ward[SUP] 1 3 4 7 [/SUP], Ara Darzi[SUP] 3 4 13 [/SUP], Graham S Cooke[SUP] 3 4 10 [/SUP], Christl A Donnelly[SUP] #[/SUP][SUP] 1 7 8 [/SUP], Marc Chadeau-Hyam[SUP] #[/SUP][SUP] 1 2 [/SUP]
Affiliations
- PMID: 35608440
- DOI: 10.1126/science.abq4411
Abstract
Rapid transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant has led to record-breaking incidence rates around the world. The REal-time Assessment of Community Transmission-1 (REACT-1) study has tracked SARS-CoV-2 infection in England using reverse transcription polymerase chain reaction (RT-PCR) results from self-administered throat and nose swabs from randomly selected participants aged 5+ years, approximately monthly from May 2020 to March 2022. Weighted prevalence in March 2022 was the highest recorded in REACT-1 at 6.37% (N=109,181) with Omicron BA.2 largely replacing BA.1. Prevalence was increasing overall with the greatest increase in those aged 65-74 and 75+ years. This was associated with increased hospitalizations and deaths but at much lower levels than in previous waves against a backdrop of high levels of vaccination.