Science: Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

Treyfish · Aug 28, 2014

Ebola Outbreak Strains Sequenced

Ninety-nine publicly available genomes could help researchers working to develop diagnostics, vaccines, and therapies.
By Tracy Vence | August 28, 2014

Augustine Goba of Kenema Government Hospital diagnosed the first case of Ebola in Sierra Leone.STEPHEN GIRE

An international team led by investigators at Harvard University has sequenced 99 Ebola virus genomes isolated from the blood of 78 patients in Sierra Leone—one of four countries at the center of the largest-ever Ebola outbreak. Within these sequences, which were each made public within a matter of days post-assembly, the researchers found evidence of the rapid accumulation of mutations affecting biologically meaningful targets, which could have implications for the development of diagnostics, vaccines, and therapies. The team’s analysis of all 99 genomes was published today (August 28) in Science.

“This analysis will provide the backbone for tracking the virus as it spreads, and to see if future outbreaks outside of these countries are connected both epidemiologically and genetically,” emerging infectious diseases researcher Matthew Frieman from the University of Maryland School of Medicine who was not involved in the work told The Scientist in an e-mail. “The ability to deep sequence virus samples rapidly, inexpensively, and safely has opened up a window in to genomic surveillance that did not exist before.”

snip

“We’ve been really overwhelmed by what’s going on,” said Sabeti. “This is an extraordinary emergency on an unprecedented scale.”

Five healthcare workers who assisted the team on the ground in Sierra Leone died of Ebola. All five were infected with the virus while caring for sick patients or family members, Sabeti said. In their paper, the authors honored their deceased colleagues—five would-be coauthors on the work—who gave their lives to help others.
“These individuals were heroic and battling something extraordinarily dangerous,” said Sabeti. “Without them, this wouldn’t be possible.”
S.K. Gire et al., “Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak,” Science, doi: 10.1126/science.1259657, 2014.:tiphat:http://www.the-scientist.com/?articles.view/articleNo/40896/title/Ebola-Outbreak-Strains-Sequenced/

Treyfish · Aug 28, 2014

Re: Ebola Outbreak Strains Sequenced

Re: Ebola Outbreak Strains Sequenced

28 August 2014 Last updated at 14:00 ET

Genetic clues to spread of Ebola

By Helen Briggs Health editor, BBC News website

Scientists have tracked the spread of Ebola in West Africa, revealing genetic clues to the course of the outbreak.
Genetic analysis of patient samples suggests the virus spread from Guinea to Sierra Leone at a single funeral.
The virus is mutating and must be contained rapidly, warn African and US experts. But they say there is no evidence the virus is changing its behaviour.

The current outbreak is the largest ever, with more than 3,000 cases.
The number of cases could exceed 20,000 before the outbreak is stemmed, according to the World Health Organization.
"We've uncovered more than 300 genetic clues about what sets this outbreak apart from previous outbreaks," said Stephen Gire from the Broad Institute and Harvard University in the US.
The isolation ward at Kenema Government Hospital in Kenema, Sierra Leone
"Although we don't know whether these differences are related to the severity of the current outbreak, by sharing these data with the research community, we hope to speed up our understanding of this epidemic and support global efforts to contain it."
The data, published in Science, suggests the virus made the leap from animals to humans only once in the current outbreak.

“Start Quote

Clearly this virus is evolving, but what's not clear is whether or not the mutations it's accumulating affect the way it behaves.”

Prof Jonathan Ball Nottingham University

snip

Five of the 58 experts named on the paper died from Ebola in Sierra Leone during the study.:tiphat:http://www.bbc.com/news/health-28958495

Treyfish · Aug 28, 2014

Re: West Africa: Ebola Outbreak Strains Sequenced

Re: West Africa: Ebola Outbreak Strains Sequenced

...For starters, the data show that the virus is rapidly accumulating new mutations as it spreads through people. "We've found over 250 mutations that are changing in real time as we're watching."
While moving through the human population in West Africa, she says, the virus has been collecting mutations about twice as quickly as did while circulating in animals for the last decade or so.
"The more time you give a virus to mutate and the more human-to-human transmission you see," she says, "the more opportunities you give it to fall upon some [mutation] that could make it more easily transmissible or more pathogenic.".. :tiphat:http://www.npr.org/blogs/goatsandso...dly-mutating-as-it-spreads-across-west-africa

sharon sanders · Aug 28, 2014

Re: West Africa: Ebola Outbreak Strains Sequenced

Re: West Africa: Ebola Outbreak Strains Sequenced

<cite>
Science DOI: 10.1126/science.1259657 </cite>

Report

Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

+ Author Affiliations

<address>1Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA. </address>
<address>2Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. </address>
<address>3Kenema Government Hospital, Kenema, Sierra Leone. </address>
<address>4Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. </address>
<address>5Eastern Polytechnic College, Kenema, Sierra Leone. </address>
<address>6Institute of Evolutionary Biology, University of Edinburgh, Edinburgh EH9 3JT, UK. </address>
<address>7Systems Biology, Harvard Medical School, Boston, MA 02115, USA. </address>
<address>8Tulane University Medical Center, New Orleans, LA 70112, USA. </address>
<address>9Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. </address>
<address>10Redeemer?s University, Ogun State, Nigeria. </address>
<address>11University of Sierra Leone, Freetown, Sierra Leone. </address>
<address>12Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA. </address>
<address>13Centre for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh EH9 3JT, UK. </address>

+ Author Notes

↵? Deceased.

↵?Corresponding author. E-mail: andersen@broadinstitute.org (K.G.A.); augstgoba@yahoo.com (A.G.); psabeti@oeb.harvard.edu (P.C.S.)

↵* These authors contributed equally to this work.
↵? These authors jointly supervised this work.

Abstract

In its largest outbreak, Ebola virus disease is spreading through Guinea, Liberia, Sierra Leone, and Nigeria. We sequenced 99 Ebola virus genomes from 78 patients in Sierra Leone to ~2,000x coverage. We observed a rapid accumulation of interhost and intrahost genetic variation, allowing us to characterize patterns of viral transmission over the initial weeks of the epidemic. This West African variant likely diverged from Middle African lineages ~2004, crossed from Guinea to Sierra Leone in May 2014, and has exhibited sustained human-to-human transmission subsequently, with no evidence of additional zoonotic sources. Since many of the mutations alter protein sequences and other biologically meaningful targets, they should be monitored for impact on diagnostics, vaccines, and therapies critical to outbreak response.

Received for publication 5 August 2014.
Accepted for publication 21 August 2014.

http://www.sciencemag.org/content/e...ract?sid=1da1a723-ac42-480d-8206-96feb3fcb57c

Shiloh · Aug 28, 2014

Re: West Africa: Ebola Outbreak Strains Sequenced

Re: West Africa: Ebola Outbreak Strains Sequenced

Source: http://www.npr.org/blogs/goatsandso...dly-mutating-as-it-spreads-across-west-africa

Ebola Is Rapidly Mutating As It Spreads Across West Africa
by Michaeleen Doucleff
August 28, 2014 2:08 PM ET

"In general, these viruses are amazing because they are these tiny things that can do a lot of damage," says the study's lead author, . She's a computational biology at Harvard University...

...For starters, the data show that the virus is rapidly accumulating new mutations as it spreads through people. "We've found over 250 mutations that are changing in real time as we're watching."

While moving through the human population in West Africa, she says, the virus has been collecting mutations about twice as quickly as did while circulating in animals for the last decade or so.

"The more time you give a virus to mutate and the more human-to-human transmission you see," she says, "the more opportunities you give it to fall upon some [mutation] that could make it more easily transmissible or more pathogenic."
A scientist tests a patient's blood for Ebola at the European Mobile Laboratory in Gueckedou, Guinea. The first cases reported in the outbreak occurred in a small village about eight miles outside Gueckedou.

Sabeti says she doesn't know if that's happening yet. But the rapid change in the virus' DNA could weaken the tools we have to detect Ebola or potentially treat patients...

sharon sanders · Aug 28, 2014

Re: West Africa: Ebola Outbreak Strains Sequenced

Re: West Africa: Ebola Outbreak Strains Sequenced

GenBank sequences:

http://www.ncbi.nlm.nih.gov/nuccore/?term=ebola+zaire+2014

JJackson · Aug 28, 2014

Re: West Africa: Ebola Outbreak Strains Sequenced

Re: West Africa: Ebola Outbreak Strains Sequenced

Do any of you understand EBOV sequences? I have downloaded and aligned some of the genebank sequences but have no understanding of the important sites on the genes, as I would for flu sequences. Where are the primary antigenic sites, binding sites, sites know to relate to virulance or transmission etc?

Its an -ssRNA virus, like flu, but with a single strand. It is slightly larger overall but seems to have more non-coding AAs. As with all negative sense viruses it must provide its own RNP components which I would expect to take up about half the genome - assuming they are much like influenza's.

Donners · Aug 28, 2014

Re: West Africa: Ebola Outbreak Strains Sequenced

Re: West Africa: Ebola Outbreak Strains Sequenced

While moving through the human population in West Africa, she says, the virus has been collecting mutations about twice as quickly as did while circulating in animals for the last decade or so.

That line is confusing.

Do they mean it is mutating at twice the normal rate (as "twice as quickly" seems to indicate) or twice the level of mutations that would be expected over a decade (as the latter part of the sentence seems to say).

JJackson · Aug 28, 2014

Re: West Africa: Ebola Outbreak Strains Sequenced

Re: West Africa: Ebola Outbreak Strains Sequenced

Donners said:
That line is confusing.

Do they mean it is mutating at twice the normal rate (as "twice as quickly" seems to indicate) or twice the level of mutations that would be expected over a decade (as the latter part of the sentence seems to say).

I think they mean the same. You count the number of single nucleotide changes that occur over a given time.
They found a given rate of change over time while it was replicating in its wild host but over the same period of time in humans they got twice that rate.
An increase in the rate of mutations is found when any organism is adapting to a new environment. Here I suspect the virus is adapting to its new host so the rate of apparent change has doubled. Note it is apparent rate that has changed i.e. the rate that changes have become fixed in the population. The actual rate of SNP substitution probably will not have changed but, absent selection pressure, they are out performed by the wild type. To get actual rate change I would go for an energetic ionizing radiation source - plutonium would do the trick.

Vibrant62 · Aug 28, 2014

Re: West Africa: Ebola Outbreak Strains Sequenced

Re: West Africa: Ebola Outbreak Strains Sequenced

Powerful article from Washington Post

Ebola virus has mutated during course of outbreak

Ebola virus has mutated during course of outbreak

By Brady Dennis August 28 at 2:02 PM
http://www.washingtonpost.com/natio...235aaa-2ecb-11e4-bb9b-997ae96fad33_story.html

The Ebola virus sweeping through West Africa has mutated repeatedly during the current outbreak, a fact that could hinder diagnosis and treatment of the devastating disease, according to scientists who have genetically sequenced the virus in scores of victims.

snip

It also provided another reminder of the deep toll the outbreak has taken on health workers and others in the affected areas, as five of the paper?s more than 50 co-authors died from Ebola before publication.

In a collaboration led by scientists at Harvard University and aided by officials at Sierra Leone?s health ministry, researchers sequenced Ebola virus genomes from 78 patients beginning in the early days of the outbreak this spring. Those 99 samples ? some patients were tested more than once ? suggested that the outbreak began with a single human infection before spreading rapidly, like a spark that grows into a wildfire.

snip

Researchers said the data suggests that the virus spread from an animal host, possibly bats, and that diverged around 2004 from an Ebola strain in central Africa, where previous outbreaks have occurred.

snip

Thursday?s study also details hundreds of genetic mutations that make the current Ebola outbreak different from any in the past. Some of those changes have the potential to affect the accuracy of diagnostic tests or the effectiveness of vaccines and treatments under development for the disease.

?We?ve uncovered more than 300 genetic clues about what sets this outbreak apart from previous outbreaks,? Stephen Gire, one of the study?s co-authors and an infectious disease researcher at Harvard, said in an announcement about the findings. ?Although we don?t know whether these differences are related to the severity of the current outbreak, by sharing these data with the research community, we hope to speed up our understanding of this epidemic and support global efforts to contain it.?

Sabeti said researchers are expecting to receive additional Ebola samples soon from Nigeria. They plan to sequence those, as well, and release the data as soon as possible.

snip

Fauci said Thursday?s findings also underscore the necessity to get the outbreak under control before the Ebola virus continues to morph.

?We?re left with a situation where if, in fact, this thing smolders on and on, we know mutations will accumulate,? he said. ?And that has its own set of problems. We?ve really got to get this thing shut off.?

Sabeti said she that since she and her colleagues published the sequencing data, they have heard from companies working on vaccines and treatments, as well as by researchers developing new diagnostic tests, who want to understand how the mutations could affect those efforts. Only through such collaboration, she said, can scientists tackle the current outbreak with the speed it deserves.

?There?s nothing you should crowdsource more than an epidemic. It has this urgency where we need every person working on it,? Sabeti said. ?It took a village to make this paper happen. It will take a planet to help get this virus under control.?

Donners · Aug 28, 2014

Re: West Africa: Ebola Outbreak Strains Sequenced

Re: West Africa: Ebola Outbreak Strains Sequenced

This part is fascinating:

The analysis reveals that the outbreak in Sierra Leone was sparked by at least two distinct viruses, introduced from Guinea at about the same time. It is unclear whether the herbalist was infected with both variants, or whether perhaps another funeral attendee was independently infected. One Ebola virus lineage disappears from patient samples taken later in the outbreak, while a third lineage appears. That lineage—tied to a nurse who was traveling to reach a hospital but died along the way—seems to have originated when one of the lineages present at the funeral gained a new mutation. This third lineage was spread, Garry says, via a truck driver who transported the nurse, as well as others who cared for her in the town where she died.

Gemineye · Aug 28, 2014

Genomic sequencing reveals more than 300 mutations in 2014 Ebola virus

Genomic sequencing reveals more than 300 mutations in 2014 Ebola virus

From Healio Infectious News
Gire SK. Science. 2014;doi:10.1126/science.1259657.

August 28, 2014

...With collaboration with the Sierra Leone Ministry of Health and Sanitation, Pardis Sabeti, MD, DPhil, of the Broad Institute and Harvard University, and colleagues sequenced Ebola virus genomes collected from 78 patients with the virus in Sierra Leone during the first 24 days of the outbreak. Along with the mutations, which make the 2014 Ebola virus distinct from the viral genomes tied to previous Ebola outbreaks, the researchers found sequence variations indicating that the outbreak started from a single introduction into humans...

http://www.healio.com/infectious-di...s-more-than-300-mutations-in-2014-ebola-virus

gsgs · Sep 24, 2014

Re: Science: Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

http://www.virology.ws/2014/09/18/wh...t-ebola-virus/
http://www.twiv.tv/2014/09/21/twiv-303/

here http://www.sciencemag.org/content/345/6202/1369.full they gibe 8e-4 mutations per site per year,
which would be roughly 1/4 of influenza-A, 1/2 of influenza-B.
they don't mention the 1997 paper which wikipedia refers to when they say
ebola mutates 100 times slower than influenza :
http://mbe.oxfordjournals.org/content/14/8/800

only the glycoprotein, the rest mutates faster ?
the full 1976 virus is at genbank, it has 561 differences to the 2014 strain,
it seems to be a (almost) direct ancester, thus giving a rate of
561/18000/38=8e-4 mutations per site per year

5 types of ebola, the other 4 types are very different, e.g. Reston-Ebola
has 6184 differences (--> >300years)

-----------------------------
http://www.ncbi.nlm.nih.gov/nuccore/?term=ebola
Zaire Ebola virus virion spike glycoprotein and small secreted non-structural glycoprotein
sGP (GP) gene, complete cds
2,408 bp linear RNA
http://www.ncbi.nlm.nih.gov/nuccore/U77384.1
positions 5898-8344 out of 18959 in my (1976,1996,2014) alignment
83 mutations 1976-2014 in that area --> rate = 83/2447/38 = 8.9e-4 per site per year
-------------------------------

ahh, the 1997 paper considers _nonsynonymous mutations_ !
> Molecular evolutionary analyses for Ebola and Marburg viruses were conducted with the
> aim of elucidating evolutionary features of these viruses. In particular, the rate of
> nonsynonymous substitutions for the glycoprotein gene of Ebola virus was estimated
> to be, on the average, 3.6 X 1O-5 per site per year.
> Marburg virus was also suggested to be evolving at a similar rate. Those rates were
> a hundred times slower than those of retroviruses and human influenza A virus,

so it seems they compared nonsynonymous ebola mutations with synonymous influenza
to arrive at their "hundred times slower" , which would be really silly.
And wikipedia repeats it.
http://en.wikipedia.org/wiki/Ebolavirus

incredible ... one of the co-authors himself examined the influenza mutation rate in 1994
and that paper was referred to :

GOJOBORI, T., Y. YAMAGUCHI, K. IKEO, and M. MIZOKAMI.
1994. Evolution of pathogenic viruses with special refer-
ence to the rates of synonymous and nonsynonymous sub-
stitutions. Jpn. J. Genet. 69:48 l-488.

https://www.jstage.jst.go.jp/article...5_481/_article

they give 13.1e-3 for synonymous flu-A-HA and 3.59e-3 for nonsynonymous
(only at antigenic sites ?)

referring to Gojobori et.al., 1990 , molecular clock ... :

---------------------------------------------------
Collecting the reports on human H3 hemagglutinin gene
sequences, K. Oguchi and T. Gojobori (personal communi-
cation) estimated the rates of synonymous and nonsynony-
mous substitutions by the method of Nei and Gojobori (12).
The rate (13.1 x 10-3 per site per year) of synonymous
substitutions was much higher than that (3.59x 10-3 per site
per year) ofnonsynonymous substitutions (Fig. 1).
------------------------------------------------------
12. Nei, M. & Gojobori, T. (1986) Mol. Biol. Evol. 3, 418-426.
so, now we are at 1986 as the base for the wiki-quote.
Much happened since then wrt. sequencing.

the word "influenza" was not found with OCR in that 1986 article

so they didn't compare nonsynonymous ebola with synonymous influenza
but it remains unclear how they arrived at their erraneous influenza
mutation rates in the first place in 1986 and maintained that until
at least 1994. [and wikipedia still has it in 2014 !]

however, checking mutations in HA of nowadays available
H3N2 , I get ~4e-3 mutations per nucleotide-position per year in HA,
upto 5e-3 after hostswitch or important reassortments and
about 1/3 of these are nonsynonymous.
4e-3 in HA, 3e-3 in other segments. Nothing whatsoever justifies
that "100 times slower". Maybe 5 times slower when compared with
flu-A HAs in humans.

gsgs · Sep 24, 2014

Re: West Africa: Ebola Outbreak Strains Sequenced

Re: West Africa: Ebola Outbreak Strains Sequenced

sharon sanders said:
GenBank sequences:

http://www.ncbi.nlm.nih.gov/nuccore/?term=ebola+zaire+2014

I'm not sure how to get all the sequences.
You may have to search also for "ebolavirus" (one word)

I have got 296 full genomes of the ebola (Zaire) now. (fasta)
And the headers are not so nice as with flu, dates and locations

when I have several of the 5 ebolatypes (Zaire,Bundibugya,Reston,Sudan,Tai_Forest)
mixed in one file, then I can't align them with mafft or kalign

gsgs · Sep 24, 2014

Re: West Africa: Ebola Outbreak Strains Sequenced

Re: West Africa: Ebola Outbreak Strains Sequenced

JJackson said:
Do any of you understand EBOV sequences? I have downloaded and aligned some of the genebank sequences but have no understanding of the important sites on the genes, as I would for flu sequences. Where are the primary antigenic sites, binding sites, sites know to relate to virulance or transmission etc?

Its an -ssRNA virus, like flu, but with a single strand. It is slightly larger overall but seems to have more non-coding AAs. As with all negative sense viruses it must provide its own RNP components which I would expect to take up about half the genome - assuming they are much like influenza's.

7 proteins, genbank also lists them, but I don't know yet what they do,
where antigenic sites are etc.

http://en.wikipedia.org/wiki/Ebolavirus

gb

gsgs · Sep 24, 2014

Re: West Africa: Ebola Outbreak Strains Sequenced

Re: West Africa: Ebola Outbreak Strains Sequenced

JJackson said:
I think they mean the same. You count the number of single nucleotide changes that occur over a given time.
They found a given rate of change over time while it was replicating in its wild host but over the same period of time in humans they got twice that rate.
An increase in the rate of mutations is found when any organism is adapting to a new environment. Here I suspect the virus is adapting to its new host so the rate of apparent change has doubled. Note it is apparent rate that has changed i.e. the rate that changes have become fixed in the population. The actual rate of SNP substitution probably will not have changed but, absent selection pressure, they are out performed by the wild type. To get actual rate change I would go for an energetic ionizing radiation source - plutonium would do the trick.

twice as much -if correct- would be a surprisingly big increase,
as compared with flu, where I get a ~30% increase and in HA only
in the years after the 1968 pandemic.
The mutation rate itself could be somehow encoded in the genome,
so flu-B mutates at only half the rate as flu-A.
But I never observed an actual change of mutation rate by mutation ?!?

gsgs · Sep 24, 2014

Re: Science: Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

OK, I got 142 different full ebola_zaire genomes from genbank, (into file: ebozai2)
and aligned them.
I'd count 6 different strains

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                                                                                                                                739050270506147134563609478158299440104492531900254393434816897995707675760324358237395579439229725954956690396700692572840924362303642813014309701561864328129258893752326647813681787048680778359014916284338081081102485139501240295856746148103938749657202434253318513260679806719192820280191055727232637845923023207512833582451456760264538188010476047091178112343060787128741094423267810905233123791223571259972446726891565516128592367038998505139581524868881580372907034718348495293628982246959204658297743249670774604695664076061456525894949076834536862596842347562905272862680668188079237998192914548252024365706981714065246451615191806427298200729068965890713897129545921717468142035247484416555727524643461053967045386408420173303315197632852246265912967753384014810358061670069452528234143953962254301860140894620936929815294943436227323302061687839056106376866641223798272302665028466796181034334767157306942768795437893144483228314647709810257746519226672547541907040781002612707172455979401588647045188448271654658606369233541357 
-codon-position-----------------------------------------------------------------------------------------------------------------112 2 211222222 2 1122  22  11212121221 11121 21 11111112111121111111111111111111 111111111111211 121111 1    122 111111111121111 1111 11 1   121121111111211 22  2 2112   212  22222 12 221 2 21121222122222222221 2222222222 2 111 1  1221 2 1122 121 22212222221222222222222222222221222222 212  2 21 2   12 1 22 11222212  211121111 2  1 22 2112 2  112 22222222 22122222222222212222  2221    11  2112 21 2 22112 1  21 12 2 2 11221 2 222 122 2122222222222 22 22221  22 2121112 1122  1 12    22121   1212111211211111111121 1211112112211  121111  221 12212 2 21  1211  2 2  12121 2121 221  1212112  111   22 2 122222221 222222222 2 2112211222221221  121  1 1  2 122121211  2 222222222 22222 22222 2222  2 222 2 22222222222 2222222222221222222222222222222 222222212 222221222222 222222222222222222 12 222222222222 1 22221222  222222 22222222222222222121222212222222222 22222 22222 222  12 21222   2 1 1122 222 222 1 121222 222222222212222 122   222 2222222222 22 2222222222222 2 11 12   1 1 1  1222 1 1 2121   21112121112 1 1  11121221111 2 11 2  
---Index------------------------------------------------------------------------------------------------------------------------TGTACCGGAATCATGTAACGTTACCCCACGCCAATAGAGCGATAAATGGGTTCCATTTATTCAACTGGCCTGAGTGTTCAGGAATTACGGCACCGACGCGCCCGGACCCCCGAGTCTTCCCCATTATTAATTCCATAATTAGACTTTTGCTGCTCAAGTTTTAACCGTTTAGGCTGCCCCTGGCATCGCTGTTAGAAGGTCAGCATTTGTAGAATTCTGGAAACTTAACTTCAGATACTGACCTTAATAGTCGAGGTCCGCCTTCGCGTACTTTTATACGTCTCGAGTTCATATCATCTAACTCGGCTTAGAGCTCACCTACACGGGGGAGATATCTTGACTGAAGTAGTTGTTATATGCTGGGACTCATCGTGGTTCTGGCGCGCAGAAAAGTCTCTCACCTGTGTGAGCCCTTTACGTTCTGCATTGAAGATCTTACACGACGCTGACCTCTCAATCTCCCAACTACCAGCCCCAAGGGAAAAAATCGACACCTTTCAACCACCGATAGCACACAAACATAGAATATATACCCGGTTTATTTACTCTGTCACGGTACAGCAAGCATTCCTCGGTAGGAATACGCGACCTTGAAAGTAAGACAACGTAATCCTAGCACCTACGTATATACAGGACAGGGAACTCCTGTTCTTCAGACTGAAACCGTCACTGGAATAAAGATTCTTGCATCGCACATAGTAGCTCGCTTGCGGAACTCAAACTCATACGAAAGTCTGCCGGCTTTAAAACGCGAGCAATGTCTGCGCCCTAGTTACTAGCCATCCAGTTTAGCTGTTATGCCAACTAAGGTATCAGGCCTAATAAAGAACGTTCAAGCGGACCTACTCCACTTTGTATTATCCCACAGCGAATTTCCCACTTAGGGGAACGGAAGCGAGGAGCTCCAACAGATTCACATGAGCGCATGCAGGTGCTGCTCCGCGGTGGCTCCTAGGGCGATTTTCACACTTTTCCTGTTGTGGATCCAGGTACTGCGCTCTGGATCACGCGGGAATGCTATTCCTTAATCGTCGATGC 
   1 >gi667852840gbKM233069.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3770.1, partial genome     ..........................................................................................................................................................................................G.....................................................................................................................................................................................................................................................................................................................................................................................................................A.......................................................................................................................................A.....................................................................................................................................................................................................................................................................................................................        3      3 ,      3      3       1:>gi667852840gbKM233069.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3770.1, partial genome     
   2 >gi667852851gbKM233070.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3770.2, partial genome     ..........................................................................................................................................................................................G.....................................................................................................................................................................................................................................................................................................................................................................................................................A.......................................................................................................................................A.....................................................................................................................................................................................................................................................................................................................        3      3 ,      3      3       2:>gi667852851gbKM233070.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3770.2, partial genome     
   3 >gi667852562gbKM233042.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM119, partial genome       ..........................................................................................................................................................................................G.....................................................................................................................................................................................................................................................................................................................................................................................................................A.......................................................................................................................................A.....................................................................................................................................................................................................................................................................................................................        4      3 ,      3      3       3:>gi667852562gbKM233042.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM119, partial genome       
   4 >gi667853072gbKM233091.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3817, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        7      1 ,      4      1       4:>gi667853072gbKM233091.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3817, partial genome       
   5 >gi667853259gbKM233109.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3846, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        3      1 ,      3      1       5:>gi667853259gbKM233109.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3846, partial genome       
   6 >gi667852788gbKM233064.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3765.2, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.........................................................................................................................................................................................................................................................................................................................................................................................................................................................----       10      5 ,      1      1       6:>gi667852788gbKM233064.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3765.2, partial genome     
   7 >gi667852696gbKM233055.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3734.1, partial genome     ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        3      0 ,      0      0       7:>gi667852696gbKM233055.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3734.1, partial genome     
   8 >gi667853343gbKM233117.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-NM042.2, partial genome     --..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.......................................................................................................................................................................................................................................................................................................................................................................................................................................................------       14      9 ,      1      1       8:>gi667853343gbKM233117.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-NM042.2, partial genome     
   9 >gi667852656gbKM233051.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3713.3, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A..............................................................................................................................................................................................T..............................................................................................................................................................................................................................................................        2      2 ,      2      2       9:>gi667852656gbKM233051.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3713.3, partial genome     
  10 >gi667852635gbKM233049.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3707, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      1 ,      1      1      10:>gi667852635gbKM233049.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3707, partial genome       
  11 >gi667852489gbKM233035.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM104, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        3      1 ,      2      1      11:>gi667852489gbKM233035.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM104, partial genome       
  12 >gi667853353gbKM233118.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-NM042.3, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A...............................................................................................................................................................................................................................................................................................................................................................................................................................................--------------       20     15 ,      1      1      12:>gi667853353gbKM233118.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-NM042.3, partial genome     
  13 >gi667852726gbKM233058.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3750.1, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A....C........................................................................................................................................................................................................................................................................................................................................................................................................................................................        5      2 ,      2      2      13:>gi667852726gbKM233058.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3750.1, partial genome     
  14 >gi667852736gbKM233059.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3750.2, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A....C.....................................................................................................................................................................................................................................................................................................................................................................................................................................................---        9      5 ,      2      2      14:>gi667852736gbKM233059.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3750.2, partial genome     
  15 >gi667852706gbKM233056.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3735.1, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      1 ,      1      1      15:>gi667852706gbKM233056.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3735.1, partial genome     
  16 >gi667853311gbKM233114.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3856.3, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.........................................................................................................................................C...................................................................................................................................................................................................................................................................................................................        2      2 ,      2      2      16:>gi667853311gbKM233114.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3856.3, partial genome     
  17 >gi667853301gbKM233113.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3856.1, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.........................................................................................................................................C...................................................................................................................................................................................................................................................................................................................        2      2 ,      2      2      17:>gi667853301gbKM233113.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3856.1, partial genome     
  18 >gi667853280gbKM233111.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3850, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.........................................................................................................................................................................................................................................................................................................................................................................................................................................................----       10      5 ,      1      1      18:>gi667853280gbKM233111.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3850, partial genome       
  19 >gi667852967gbKM233081.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3800, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      0 ,      0      0      19:>gi667852967gbKM233081.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3800, partial genome       
  20 >gi667852988gbKM233083.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3805.2, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A............................................................................................................................................................................................................................................................................................................................................................................................................................................................-        5      2 ,      1      1      20:>gi667852988gbKM233083.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3805.2, partial genome     
  21 >gi667853020gbKM233086.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3809, partial genome       ..............................................................................................................................................................................................................................................................................A.................................................................................................................................................................................................................................................................................................................................A............................................................................................................................................................................................................................................................................................................................................................................................................................................................-        6      3 ,      2      2      21:>gi667853020gbKM233086.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3809, partial genome       
  22 >gi667853062gbKM233090.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3816, partial genome       ..............................................................................................................................................................................................................................................................................A.................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        5      2 ,      2      2      22:>gi667853062gbKM233090.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3816, partial genome       
  23 >gi667853228gbKM233106.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3840, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      1 ,      1      1      23:>gi667853228gbKM233106.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3840, partial genome       
  24 >gi667853113gbKM233095.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3821, partial genome       ..............................................................................................................................................................................................................................................................................A.................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        5      2 ,      2      2      24:>gi667853113gbKM233095.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3821, partial genome       
  25 >gi667853124gbKM233096.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3822, partial genome       ..............................................................................................................................................................................................................................................................................A.................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        2      2 ,      2      2      25:>gi667853124gbKM233096.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3822, partial genome       
  26 >gi667853332gbKM233116.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-NM042.1, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        2      1 ,      1      1      26:>gi667853332gbKM233116.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-NM042.1, partial genome     
  27 >gi667852625gbKM233048.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM124.4, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A................................................................................................................................................................................C...........................................................................................................................................................................................................................................................................-        6      3 ,      2      2      27:>gi667852625gbKM233048.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM124.4, partial genome     
  28 >gi667852614gbKM233047.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM124.3, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        2      1 ,      1      1      28:>gi667852614gbKM233047.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM124.3, partial genome     
  29 >gi667852552gbKM233041.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM115, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        4      1 ,      1      1      29:>gi667852552gbKM233041.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM115, partial genome       
  30 >gi661348705gbKM034560.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3682.1, partial genome     ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        0      0 ,      0      0      30:>gi661348705gbKM034560.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3682.1, partial genome     
  31 >gi667852500gbKM233036.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM106, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        4      1 ,      1      1      31:>gi667852500gbKM233036.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM106, partial genome       
  32 >gi667852510gbKM233037.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM110, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        2      1 ,      1      1      32:>gi667852510gbKM233037.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM110, partial genome       
  33 >gi667852604gbKM233046.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM124.2, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        4      1 ,      1      1      33:>gi667852604gbKM233046.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM124.2, partial genome     
  34 >gi667852676gbKM233053.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3724, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        2      1 ,      2      1      34:>gi667852676gbKM233053.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3724, partial genome       
  35 >gi667852757gbKM233061.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3752, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A................................................................................................................................................................................C............................................................................................................................................................................................................................................................................        5      2 ,      2      2      35:>gi667852757gbKM233061.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3752, partial genome       
  36 >gi667853322gbKM233115.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3857, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A................................................................................................................................................................................C...........................................................................................................................................................................................................................................................................-        6      3 ,      2      2      36:>gi667853322gbKM233115.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3857, partial genome       
  37 >gi667852861gbKM233071.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3771, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        2      1 ,      1      1      37:>gi667852861gbKM233071.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3771, partial genome       
  38 >gi667852882gbKM233073.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3786, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      0 ,      0      0      38:>gi667852882gbKM233073.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3786, partial genome       
  39 >gi667852924gbKM233077.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3795, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        2      0 ,      0      0      39:>gi667852924gbKM233077.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3795, partial genome       
  40 >gi667852934gbKM233078.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3796, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      0 ,      0      0      40:>gi667852934gbKM233078.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3796, partial genome       
  41 >gi667852957gbKM233080.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3799, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      0 ,      1      0      41:>gi667852957gbKM233080.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3799, partial genome       
  42 >gi667852999gbKM233084.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3807, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      0 ,      0      0      42:>gi667852999gbKM233084.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3807, partial genome       
  43 >gi667852903gbKM233075.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3788, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      0 ,      1      0      43:>gi667852903gbKM233075.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3788, partial genome       
  44 >gi667853239gbKM233107.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3841, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        3      0 ,      0      0      44:>gi667853239gbKM233107.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3841, partial genome       
  45 >gi667853103gbKM233094.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3820, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      0 ,      0      0      45:>gi667853103gbKM233094.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3820, partial genome       
  46 >gi667853218gbKM233105.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3838, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      0 ,      0      0      46:>gi667853218gbKM233105.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3838, partial genome       
  47 >gi667853134gbKM233097.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3823, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      0 ,      1      0      47:>gi667853134gbKM233097.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3823, partial genome       
  48 >gi667853249gbKM233108.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3845, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        2      1 ,      1      1      48:>gi667853249gbKM233108.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3845, partial genome       
  49 >gi667853270gbKM233110.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3848, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A................................................................................................................................................................................C............................................................................................................................................................................................................................................................................        2      2 ,      2      2      49:>gi667853270gbKM233110.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3848, partial genome       
  50 >gi667853291gbKM233112.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3851, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A................................................................................................................................................................................C............................................................................................................................................................................................................................................................................        3      2 ,      2      2      50:>gi667853291gbKM233112.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3851, partial genome       
  51 >gi661348675gbKM034557.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3677.2, partial genome     ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        0      0 ,      0      0      51:>gi661348675gbKM034557.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3677.2, partial genome     
  52 >gi661348665gbKM034556.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3677.1, partial genome     ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        0      0 ,      0      0      52:>gi661348665gbKM034556.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3677.1, partial genome     
  53 >gi667852582gbKM233044.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM121, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        2      0 ,      1      0      53:>gi667852582gbKM233044.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM121, partial genome       
  54 >gi667853009gbKM233085.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3808, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        3      0 ,      0      0      54:>gi667853009gbKM233085.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3808, partial genome       
  55 >gi661348625gbKM034552.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM098, partial genome       .............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................-        4      1 ,      0      0      55:>gi661348625gbKM034552.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM098, partial genome       
  56 >gi667852542gbKM233040.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM113, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        2      1 ,      1      1      56:>gi667852542gbKM233040.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM113, partial genome       
  57 >gi667852521gbKM233038.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM111, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        2      1 ,      1      1      57:>gi667852521gbKM233038.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM111, partial genome       
  58 >gi667852716gbKM233057.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3735.2, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      1 ,      1      1      58:>gi667852716gbKM233057.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3735.2, partial genome     
  59 >gi667852945gbKM233079.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3798, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        4      1 ,      1      1      59:>gi667852945gbKM233079.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3798, partial genome       
  60 >gi667852767gbKM233062.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3758, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        0      0 ,      0      0      60:>gi667852767gbKM233062.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3758, partial genome       
  61 >gi667852778gbKM233063.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3764, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      1 ,      1      1      61:>gi667852778gbKM233063.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3764, partial genome       
  62 >gi667852572gbKM233043.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM120, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        3      0 ,      1      0      62:>gi667852572gbKM233043.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM120, partial genome       
  63 >gi667853051gbKM233089.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3814, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        3      1 ,      1      1      63:>gi667853051gbKM233089.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3814, partial genome       
  64 >gi667853166gbKM233100.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3826, partial genome       ......................................................C.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        2      2 ,      2      2      64:>gi667853166gbKM233100.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3826, partial genome       
  65 >gi667853093gbKM233093.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3819, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        5      1 ,      2      1      65:>gi667853093gbKM233093.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3819, partial genome       
  66 >gi667852914gbKM233076.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3789.1, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.........................................................................................................................................................................................................................................................................................................................................................................................................................................................----        9      5 ,      1      1      66:>gi667852914gbKM233076.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3789.1, partial genome     
  67 >gi667852872gbKM233072.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3782, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        0      0 ,      0      0      67:>gi667852872gbKM233072.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3782, partial genome       
  68 >gi667852686gbKM233054.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3729, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        0      0 ,      0      0      68:>gi667852686gbKM233054.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3729, partial genome       
  69 >gi667852747gbKM233060.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3750.3, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A........................................................................................................................................................................................................................................................................................................................................................................................................................................................-----       11      6 ,      1      1      69:>gi667852747gbKM233060.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3750.3, partial genome     
  70 >gi667852592gbKM233045.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM124.1, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        3      1 ,      1      1      70:>gi667852592gbKM233045.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM124.1, partial genome     
  71 >gi667852666gbKM233052.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3713.4, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A..............................................................................................................................................................................................T..............................................................................................................................................................................................................................................................        2      2 ,      2      2      71:>gi667852666gbKM233052.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3713.4, partial genome     
  72 >gi667852646gbKM233050.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3713.2, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A..............................................................................................................................................................................................T..............................................................................................................................................................................................................................................................        2      2 ,      2      2      72:>gi667852646gbKM233050.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3713.2, partial genome     
  73 >gi667852978gbKM233082.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3805.1, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A............................................................................................................................................................................................................................................................................................................................................................................................................................................................-        5      2 ,      1      1      73:>gi667852978gbKM233082.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3805.1, partial genome     
  74 >gi667852531gbKM233039.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM112, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        1      1 ,      1      1      74:>gi667852531gbKM233039.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM112, partial genome       
  75 >gi667853176gbKM233101.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3827, partial genome       ......................................................C.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        5      2 ,      2      2      75:>gi667853176gbKM233101.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3827, partial genome       
  76 >gi667853207gbKM233104.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3834, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A................................................................................................................................................................................C............................................................................................................................................................................................................................................................................        4      2 ,      2      2      76:>gi667853207gbKM233104.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3834, partial genome       
  77 >gi667853145gbKM233098.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3825.1, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A................................................................................................................................................................................C............................................................................................................................................................................................................................................................................        2      2 ,      2      2      77:>gi667853145gbKM233098.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3825.1, partial genome     
  78 >gi667853186gbKM233102.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3829, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A................................................................................................................................................................................C............................................................................................................................................................................................................................................................................        3      2 ,      3      2      78:>gi667853186gbKM233102.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3829, partial genome       
  79 >gi667853155gbKM233099.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3825.2, partial genome     ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A................................................................................................................................................................................C............................................................................................................................................................................................................................................................................        2      2 ,      2      2      79:>gi667853155gbKM233099.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3825.2, partial genome     
  80 >gi661348635gbKM034553.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3670.1, partial genome     ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        2      0 ,      2      0      80:>gi661348635gbKM034553.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3670.1, partial genome     
  81 >gi667853041gbKM233088.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3810.2, partial genome     ............................................................................................................................................G..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A..............................................................................................................................................................................................................................................................................................................................................................................................................        3      2 ,      2      2      81:>gi667853041gbKM233088.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3810.2, partial genome     
  82 >gi667853030gbKM233087.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3810.1, partial genome     ............................................................................................................................................G..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A..............................................................................................................................................................................................................................................................................................................................................................................................................        5      2 ,      2      2      82:>gi667853030gbKM233087.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3810.1, partial genome     
  83 >gi667853082gbKM233092.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3818, partial genome       ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................................................................................................................................................................................................................................................................................................        3      1 ,      3      1      83:>gi667853082gbKM233092.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3818, partial genome       
  84 >gi661348615gbKM034551.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM096, partial genome       ........................................................................................................................................G.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................C...............................................        3      2 ,      2      2      84:>gi661348615gbKM034551.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM096, partial genome       
  85 >gi661348685gbKM034558.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3679.1, partial genome     ........................................................................................................................................G.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................C...............................................        4      2 ,      2      2      85:>gi661348685gbKM034558.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3679.1, partial genome     
  86 >gi667852893gbKM233074.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3787, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................A.................................................................................................................................................................................        5      2 ,      2      2      86:>gi667852893gbKM233074.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3787, partial genome       
  87 >gi667853197gbKM233103.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3831, partial genome       ..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.............................................................................................................................................................................A.................................................................................................................................................................................        2      2 ,      2      2      87:>gi667853197gbKM233103.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3831, partial genome       
  88 >gi667852798gbKM233065.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3769.1, partial genome     ..........................................................................................................................................................................................................................................................C.....................................C.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        3      2 ,      2      2      88:>gi667852798gbKM233065.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3769.1, partial genome     
  89 >gi667852830gbKM233068.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3769.4, partial genome     ..........................................................................................................................................................................................................................................................C.....................................C.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        3      2 ,      2      2      89:>gi667852830gbKM233068.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3769.4, partial genome     
  90 >gi667852819gbKM233067.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3769.3, partial genome     ..........................................................................................................................................................................................................................................................C.....................................C.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        3      2 ,      2      2      90:>gi667852819gbKM233067.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3769.3, partial genome     
  91 >gi667852809gbKM233066.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3769.2, partial genome     ..........................................................................................................................................................................................................................................................C.....................................C.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................        5      2 ,      2      2      91:>gi667852809gbKM233066.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3769.2, partial genome     
  92 >gi661348735gbKM034563.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3687.1, partial genome     ---------.....................................C..................................................................................---------................................................................................................................................................................................................................................................................-------.....................................................................................................A....................................................................----.........................................................................................................................................................................................................................................................................................G.......................................................................T.................................................................................................-----.......       52     38 ,      5      4      92:>gi661348735gbKM034563.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3687.1, partial genome     
  93 >gi661348655gbKM034555.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3676.2, partial genome     ..............................................C.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.................................................................................................................................................................................................................................................................................................................................................................G.......................................................................T.............................................................................................................        4      4 ,      4      4      93:>gi661348655gbKM034555.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3676.2, partial genome     
  94 >gi661348695gbKM034559.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3680.1, partial genome     ..............................................C.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.................................................................................................................................................................................................................................................................................................................................................................G.......................................................................T.............................................................................................................        6      4 ,      5      4      94:>gi661348695gbKM034559.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3680.1, partial genome     
  95 >gi661348605gbKM034550.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM095, partial genome       ..............................................C.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................A....................................................................--...........................................................................................................................................................................................................................................................................................G.......................................................................T.............................................................................................................        7      6 ,      4      4      95:>gi661348605gbKM034550.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-EM095, partial genome       
  96 >gi661348595gbKM034549.1, Zaire ebolavirus isolate H.sapiens-wt/SLE/2014/ManoRiver-EM095B, partial genome                  ..............................................C.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................A....................................................................--...........................................................................................................................................................................................................................................................................................G.......................................................................T............................................................................................................-       11      7 ,      4      4      96:>gi661348595gbKM034549.1, Zaire ebolavirus isolate H.sapiens-wt/SLE/2014/ManoRiver-EM095B, partial genome                  
  97 >gi661348645gbKM034554.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3676.1, partial genome     ..............................................C.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.................................................................................................................................................................................................................................................................................................................................................................G.......................................................................T.............................................................................................................        4      4 ,      4      4      97:>gi661348645gbKM034554.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3676.1, partial genome     
  98 >gi661348715gbKM034561.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3683.1, partial genome     ..............................................C.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.................................................................................................................................................................................................................................................................................................................................................................G.......................................................................T.............................................................................................................        8      4 ,      5      4      98:>gi661348715gbKM034561.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3683.1, partial genome     
  99 >gi661348725gbKM034562.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3686.1, partial genome     ..............................................C.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................A.................................................................................................................................................................................................................................................................................................................................................................G.......................................................................T.............................................................................................................        6      4 ,      6      4      99:>gi661348725gbKM034562.1, Zaire ebolavirus isolate Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3686.1, partial genome     
 100 >gi674810549gbKJ660346.2, Zaire ebolavirus isolate H.sapiens-wt/GIN/2014/Kissidougou-C15, complete genome                  ..............................................C.............................................T...........................................................................................................................................................................................................................................................................C.............................................................................................................................................A.................................................................................................................................................................................................................................................................................................................................................................G.......................................................................T.............................................................................................................        6      6 ,      6      6     100:>gi674810549gbKJ660346.2, Zaire ebolavirus isolate H.sapiens-wt/GIN/2014/Kissidougou-C15, complete genome                  
 101 >gi674810554gbKJ660348.2, Zaire ebolavirus isolate H.sapiens-wt/GIN/2014/Gueckedou-C05, complete genome                    ..............................................C.............................................T...........................................................................................................................................................................................................................................................................C.............................................................................................................................................A....................................................................................................................................................................................................................................................................A.............................................................................T..............G.......................................................................T.............................................................................................................       11      8 ,     11      8     101:>gi674810554gbKJ660348.2, Zaire ebolavirus isolate H.sapiens-wt/GIN/2014/Gueckedou-C05, complete genome                    
 102 >gi674810552gbKJ660347.2, Zaire ebolavirus isolate H.sapiens-wt/GIN/2014/Gueckedou-C07, complete genome                    ..............................................C.............................................T...........................................................................................................................................................................................................................................................................C.............................................................................................................................................A....................................................................................................................................................................................................................................................................A.............................................................................T..............G.......................................................................T.............................................................................................................        9      8 ,      9      8     102:>gi674810552gbKJ660347.2, Zaire ebolavirus isolate H.sapiens-wt/GIN/2014/Gueckedou-C07, complete genome                    
 103 >gi436409299gbKC242787.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/2007/23 Luebo, complete genome                    CT.GA.AA...TG.ACGGAAGC.T..T.T.TT.GA...AA..A...CAA..CT..C.CG..T..TCA.A.G.TA.ACC.GT....CGT....T.AGTA...T..A...G.T.C...C..TATGC.G.....C.T..G.CC.AG.C...ATC..ATG.AG..C....T...GAT...TTTTC...C..AT....TAG..AC......A..CG.GGCCTC.AGG..CCCG.CC..AG...AT.TGC...C...T..AA.T..TT...A...G.CAC.....A.T.T..CC..GAG.TG.T..G..TAAT.C....T.T...C.TGTA.AAAG..CGCT.....CT.GA.GA.CACC....ATCA.AG..TG..TC...C...A.A..GCA.CGG.....C.CTT.ACACA....ACCC......C.TCCC.C.A.CTC.G..T.GT.T.ACTTCT....CTC.T.GGT.G.T.....T.GA..GCGGGGCT.CG.T....TG..A.AAAGC.A.G...G.....GA...GCTG..ATAT..CG.C.TTC..A..TGAAG...ATGGAT.....CTAT..A.GG.CTA.....CC..TG..TG.....T...GC.A.G.T.TTA.T.CG..CG...AGT.AA.GTT.G..A.G.C...TG.C.G..TTA....AAAC....G..C.T.C..G..A.GAT.G.C..T.T.TCCA...GGTAA.TGA.T..GT.G..A.TCA.T.......G..T..A....GCA..CA.AT.T...C...CG.T..C..G.CC...TCA..G.AAT.TTC..AA.......TA.GGC...A...AC.TTGTTAA.T.C.TC.TGTCCC..G.....A.GT.A.AGGCC...T.ACAG...TGGT..GGA.A.AA..T.TT....A.CCA...CA.AA.TG.ATG..CAT.A..TTTTAA.A...T.CGAA.T.G..C.TGTTTCC...A.A..A.AAG.T.GA..G.CA.AT.TAA..CTGT.TAA.......G...TAC.G.T...AGC.T      539    539 ,    539    539     103:>gi436409299gbKC242787.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/2007/23 Luebo, complete genome                    
 104 >gi436409309gbKC242788.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/2007/43 Luebo, complete genome                    CT.GA.AA...TG.ACGGAAGC.T..T.T.TT.GA...AA..A...CAA..CT..C.CG..T..TCA.A.G.TA.ACC.GT....CGT....T.AGTA...T..A...G.T.C...C..TATGC.G.....C.T..G.CC.AG.C...ATC..ATG.AG..C....T...GAT...TTTTC...C..AT....TAG..AC......A..CG.GGCCTC.AGG..CCCG.CC..AG...AT.TGC...C...T..AA.T..TT...A...G.CAC.....A.T.T..CC..GAG.TG.T..G..TAAT.C....T.T...C.TGTA.AAAG..CGCT.....CT.GA.GA.CACC....ATCA.AG..TG..TC...C...A.A..GCA.CGG.....C.CTT.ACACA....ACCC......C.TCCC.C.A.CTC.G..T.GT.T.ACTTCT....CTC.T.GGT.G.T.....T.GA..GCGGGGCT.CG.T....TG..A.AAAGC.A.G...G.....GA...GCTG..ATAT..CG.C.TTC..A..TGAAG...ATGGAT.C...CTAT..A.GG.CTA.....CC..TG..TG.....T...GC.A.G.T.TTA.T.CG..CG...AGT.AA.GTT.G..A.G.C...TG.C.G..TTA....AAAC....G..C.T.C..G..A.GAT.G.C..T.T.TCCA...GGTAA.TGA.T..GT.G..A.TCA.T.......G..T..A....GCA..CA.AT.T...C...CG.T..C..G.CC...TCA..G.AAT.TTC..AA.......TA.GGC...A...AC.TTGTTAA.T.C.TC.TGTCCC..G.....A.GT.A.AGGCC...T.ACAG...TGGT..GGA.A.AA..T.TT....A.CCA...CA.AA.TG.ATG..CAT.A..TTTTAA.A...T.CGAA.T.G..C.TGTTTCC...A.A..A.AAG.T.GA..G.CA.AT.TAA..CTGT.TAA.......G...TAC.G.T...AGC.T      547    540 ,    547    540     104:>gi436409309gbKC242788.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/2007/43 Luebo, complete genome                    
 105 >gi436409279gbKC242785.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/2007/0 Luebo, complete genome                     CT.GA.AAG..TG.ACGGAAGC.T..T.T.TT.GA...AA..A...CAA..CT..C.CG..T..TCA.A.G.TA.ACC.GT....CGT....T.AGTA...T..A...G.T.C...C..TATGC.G.....C.T..G.CC.AG.C...ATC..ATG.AG..C....T...GAT...TTTTC...C..AT....TAG..AC......A..CG.GGCCTC.AGG..CCCG.CC..AG...AT.TGC...C...T..AA.T..T....A...G.CAC.....A.T.T..CC..GAG.TG.T..G..TAAT.C....T.T...C.TGTA.AAAG..CGCT.....CT.GA.GA.CACC....ATCA.AG..TG..TC...C...A.A..GCA.CGG.....C.CTT.ACACA....ACCC......C.TCCC.C.A.CTC.G..T.GT.T.ACTTCT....CTC.T.GGT.G.T.....T.GA..GCGGGGCT.CG.T....TG..A.AAAGC.A.G...G.....GA...GCTG..ATAT..CG.C.TTC..A..TGAAG...ATGGAT.....CTAT..A.GG.CTA.....CC..TG..TG.....T...GC.A.G.T.TTA.T.CG..CG...AGT.AA.GTT.G..A.G.C...TG.C.G..TTA....AAAC....G..C.T.C..G..A.GAT.G.C..T.T.TCCA...GGTAA.TGA.T..GT.G..A.TCA.T.......G..T..A....GCA..CA.AT.T...C...CG.T..C..G.CC...TCA..G.AAT.TTC..AA.......TA.GGC...A...AC.TTGTTAA.T.C.TC.TGTCCC..G.....A.GT.A.AGGCC...T.ACAG...TGGT..GGA.A.AA..T.TT....A.CCA...CA.AA.TG.ATG..CAT.A..TTTTAA.A...T.CGAA.T.G..C.TGTTTCC...A.A..A.AAG.T.GA..G.CA.AT.TAA..CTGT.TAA.......G...TAC.G.T...AGC.T      542    539 ,    542    539     105:>gi436409279gbKC242785.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/2007/0 Luebo, complete genome                     
 106 >gi436409329gbKC242790.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/2007/5 Luebo, complete genome                     CT.GA.AAG..TG.ACGGAAGC.T..T.T.TT.GA...AA..A...CAA..CT..C.CG..T..TCA.A.G.TA.ACC.GT....CGT....T.AGTA...T..A...G.T.C...C..TATGC.G.....C.T..G.CC.AG.C...ATC..ATG.AG..C...TT...GAT...TTTTC...C..AT....TAG..AC......A..CG.GGCCTC.AGG..CCCG.CC..AG...AT.TGCC..C...T..AA.T..T....A...G.CAC.....A.T.T..CC..GAG.TG.T..G..TAAT.C....T.T...C.TGTA.AAAG..CGCT.....CT.GA.GA.CACC....ATCA.AG..TG..TC...C...A.A..GCA.CGG.....C.CTT.ACACA....ACCC......C.TCCC.C.A.CTC.G..T.GT.T.ACTTCT....CTC.T.GGT.G.T.....T.GA..GCGGGGCT.CG.T....TG..A.AAAGC.A.G...G.....GA...GCTG..ATAT..CG.C.TTC..A..TGAAG...ATGGAT.....CTAT..A.GG.CTA.....CC..TG..TG.....T...GC.A.G.T.TTA.T.CG..CG...AGT.AA.GTT.G..A.G.C...TG.C.G..TTA....AAAC....G..C.T.C..G..A.GAT.G.C..T.T.TCCA...GGTAA.TGA.T..GT.G..A.TCA.T.......G..T..A....GCA..CA.AT.T...C...CG.T..C..G.CC...TCA..G.AAT.TTC..AA.......TA.GGC...A...AC.TTGTTAA.T.C.TC.TGTCCC..G.....A.GT.A.AGGCC...T.ACAG...TGGT..GGA.A.AA..T.TT....A.CCA...CA.AA.TG.ATG..CAT.A..TTTTAA.A...T.CGAA.T.G..C.TGTTTCC...A.A..A.AAG.T.GA..G.CA.AT.TAA..CTGT.TAA.......G...TAC.G.T...AGC.T      543    541 ,    543    541     106:>gi436409329gbKC242790.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/2007/5 Luebo, complete genome                     
 107 >gi436409269gbKC242784.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/2007/9 Luebo, complete genome                     CT.GA.AA...TG.ACGGAAGC.T..T.T.TT.GA...AA..A...CAA..CT..C.CG..T..TCA.A.G.TA.ACC.GT....CGT....T.AGTA...T..A...G.T.C...C..TATGC.G.....C.T..G.CC.AG.C...ATC..ATG.AG..C....T...GAT...TTTTC...C..AT....TAG..AC......A..CG.GGCCTC.AGG..CCCG.CC..AG...AT.TGC...C...T..AA.T..T....A...G.CAC.....A.T.T..CC..GAG.TG.T..G..TAAT.C....T.T...C.TGTA.AAAG..CGCT.....CT.GA.GA.CACC....ATCA.AG..TG..TC...C...A.A..GCA.CGG.....C.CTT.ACACA....ACCC......C.TCCC.C.A.CTC.G..T.GT.T.ACTTCT....CTC.T.GGT.G.T.....T.GA..GCGGGGCT.CG.T....TG..A.AAAGC.A.G...G.....GA...GCTG..ATAT..CG.C.TTC..A..TGAAG...ATGGAT.....CTAT..A.GG.CTA.....CC..TG..TG.....T...GC.A.G.T.TTA.T.CG..CG...AGT.AA.GTT.G..A.G.C...TG.C.G..TTA....AAAC....G..C.T.C..G..A.GAT.G.C..T.T.TCCA...GGTAA.TGA.T..GT.G..A.TCA.T.......G..T..A....GCA..CA.AT.T...C...CG.T..C..G.CC...TCA..G.AAT.TTC..AA.......TA.GGC...A...AC.TTGTTAA.T.C.TC.TGTCCC..G.....A.GT.A.AGGCC...T.ACAG...TGGT..GGA.A.AA..T.TT....A.CCA...CA.AA.TG.ATG..CAT.A..TTTTAA.A...TTCGAA.T.G..C.TGTTTCC...A.A..A.AAG.T.GA..G.CA.AT.TAA..CTGT.TAA.......G...TAC.G.T...AGC.T      542    539 ,    542    539     107:>gi436409269gbKC242784.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/2007/9 Luebo, complete genome                     
 108 >gi355344232gbHQ613403.1, Zaire ebolavirus isolate M-M, partial genome                                                     CT.GA.AA...TG.ACGGAAGC.T..T.T.TT.GA...AA..A...CAA..CT..C.CG..T..TCA.A.G.TA.ACC.GT....CGT....T.AGTA...T..A...G.T.C...C..TATGC.G.....C.T..G.CC.AG.C...ATC..ATG.AG..C....T...GAT...TTTTC...C..AT....TAG..AC......A..CG.GGCCTC.AGG..CCCG.CC..AG...AT.TGC...C...T..AA.T..T....A...G.CAC.....A.T.T..CC..GAG.TG.T..G..TAAT.C....T.T...C.TGTA.AAAG..CGCT.....CT.GA.GA.CACC....ATCA.AG..TG..TC...C...A.A..GCA.CGG.....C.CTT.ACACA....ACCC......C.TCCC.C.A.CTC.G..T.GT.T.ACTTCT....CTC.T.GGT.G.T.....T.GA..GCGGGGCT.CG.T....TG..A.AAAGC.A.G...G.....GA...GCTG..ATAT..CG.C.TTC..A..TGAAG...ATGGAT.....CTAT..A.GG.CTA.....CC..TG..TG.....T...GC.A.G.T.TTA.T.CG..CG...AGT.AA.GTT.G..A.G.C...TG.C.G..TTA....AAAC....G..C.T.C..G..A.GAT.G.C..T.T.TCCA...GGTAA.TGA.T..GT.G..A.TCA.T.......G..T..A....GCA..CA.AT.T...C...CG.T..C..G.CC...TCA..G.AAT.TTC..AA.......TA.GGC...A...AC.TTGTTAA.T.C.TC.TGTCCC..G.....A.GT.A.AGGCC...T.ACAG...TGGT..GGA.A.AA..T.TT....A.CCA...CA.AA.TG.ATG..CAT.A..TTTTAA.A...TTCGAA.T.G..C.TGTTTCC...A.A..A.AAG.T.GA..G.CA.AT.TAA..CTGT.TAA.......G...TAC.G.T...A----      545    540 ,    536    536     108:>gi355344232gbHQ613403.1, Zaire ebolavirus isolate M-M, partial genome                                                     
 109 >gi355344222gbHQ613402.1, Zaire ebolavirus isolate 034-KS, partial genome                                                  CT.GA.AA...TG.ACGGAAGC.T..T.T.TT.GA...AA..A...CAA..CT..C.CG..T..TCA.A.G.TA.ACC.GT....CGT....T.AGTA...T..A...G.T.C...C..TATGC.G.....C.T..G.CC.AG.C...ATC..ATG.AG..C....T...GAT...TTTTC...C..AT....TAG..AC......A..CG.GGCCTC.AGG..CCCG.CC..AG...AT.TGC...C...T..AA.T..T....A...G.CAC.....A.T.T..CC..GAG.TG.T..G..TAAT.C....T.T...C.TGTA.AAAG..CGCT.....CT.GA.GA.CACC....ATCA.AG..TG..TC...C...A.A..GCA.CGG.....C.CTT.ACACA....ACCC......C.TCCC.C.A.CTC.G..T.GT.T.ACTTCT....CTC.T.GGT.G.T.....T.GA..GCGGGGCT.CG.T....TG..A.AAAGC.A.G...G.....GA...GCTG..ATAT..CG.C.TTC..A..TGAAG...ATGGAT.....CTAT..A.GG.CTA.....CC..TG..TG.....T...GC.A.G.T.TTA.T.CG..CG...AGT.AA.GTT.G..A.G.C...TG.C.G..TTA....AAAC....G..C.T.C..G..A.GAT.G.C..T.T.TCCA...GGTAA.TGA.T..GT.G..A.TCA.T.......G..T..A....GCA..CA.AT.T...C...CG.T..C..G.CC...TCA..G.AAT.TTC..AA.......TA.GGC...A...AC.TTGTTAA.T.C.TC.TGTCCC..G.....A.GT.A.AGGCC...T.ACAG...TGGT..GGA.A.AA..T.TT....A.CCA...CA.AA.TG.ATG..CAT.A..TTTTAA.A...T.CGAA.T.G..C.TGTTTCC...A.A..A.AAG.T.GA..G.CA.AT.TAA..CTGT.TAA.......G...TAC.G.T...A----      554    539 ,    545    535     109:>gi355344222gbHQ613402.1, Zaire ebolavirus isolate 034-KS, partial genome                                                  
 110 >gi436409319gbKC242789.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/2007/4 Luebo, complete genome                     CT.GA.AA...TG.ACGGAAGC.T..T.T.TT.GA...AA..A...CAA..CT..C.CG..T..TCA.A.G.TA.ACC.GT....CGT....T.AGTA...T..A...G.T.C...C..TATGC.G.....C.T..G.CC.AG.C...ATC..ATG.AG..C....T...GAT...TTTTC...C..AT....TAG..AC......A..CG.GGCCTC.AGG..CCCG.CC..AG...AT.TGC...C...T..AA.T..T....A...G.CAC.....A.T.T..CC..GAG.TG.T..G..TAAT.C....T.T...C.TGTA.AAAG..CGCT.....CT.GA.GA.CACC....ATCA.AG..TG..TC...C...A.A..GCA.CGG.....C.CTT.ACACA....ACCC......C.TCCC.C.A.CTC.G..T.GT.T.ACTTCT....CTC.T.GGT.G.T.....T.GA..GCGGGGCT.CG.T....TG..A.AAAGC.A.G...G.....GA...GCTG..ATAT..CG.C.TTC..A..TGAAG...ATGGAT.....CTAT..A.GG.CTA.....CC..TG..TG.....T...GC.A.G.T.TTA.T.CG..CG...AGT.AA.GTT.G..A.G.C...TG.C.G..TTA....AAAC....G..C.T.C..G..A.GAT.G.C..T.T.TCCA...GGTAA.TGA.T..GT.G..A.TCA.T.......G..T..A....GCA..CA.AT.T...C...CG.T..C..G.CC...TCA..G.AAT.TTC..AA.......TA.GGC...A...AC.TTGTTAA.TTC.TC.TGTCCC..G.....A.GT.A.AGGCC...T.ACAG...TGGT..GGA.A.AA..T.TT....A.CCA...CA.AA.TG.ATG..CAT.A..TTTTAA.A...T.CGAA.T.G..C.TGTTTCC...A.A..A.AAG.T.GA..G.CA.AT.TAA..CTGT.TAA.......G...TAC.G.T...AGC.T      541    539 ,    541    539     110:>gi436409319gbKC242789.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/2007/4 Luebo, complete genome                     
 111 >gi436409289gbKC242786.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/2007/1 Luebo, complete genome                     CT.GA.AA...TG.ACGGAAGC.T..T.T.TT.GA...AA..A...CAA..CT..C.CG..T..TCA.A.G.TA.ACC.GT....CGT....T.AGTA...T..A...G.T.C...C..TATGC.G.....C.T..G.CC.AG.C...ATC..ATG.AG..C....T...GAT...TTTTC...C..AT....TAG..AC......A..CG.GGCCTC.AGG..CCCG.CC..AG...AT.TGC...C...T..AA.T..T....A...G.CAC.....A.T.T..CC..GAG.TG.T..G..TAAT.C....T.T...C.TGTA.AAAG..CGCT.....CT.GA.GA.CACC....ATCA.AG..TG..TC...C...A.A..GCA.CGG.....C.CTT.ACACA....ACCC......C.TCCC.C.A.CTC.G..T.GT.T.ACTTCT....CTC.T.GGT.G.T.....T.GA..GCGGGGCT.CG.T....TG..A.AAAGC.A.G...G.....GA...GCTG..ATAT..CG.C.TTC..A..TGAAG...ATGGAT.....CTAT..A.GG.CTA.....CC..TG..TG.....T...GC.A.G.T.TTA.T.CG..CG...AGT.AA.GTT.G..A.G.C...TG.C.G..TTA....AAAC....G..C.T.C..G..A.GAT.G.C..T.T.TCCA...GGTAA.TGA.T..GT.G..A.TCA.T.......G..T..A....GCA..CA.AT.T...C...CG.T..C..G.CC...TCA..G.AAT.TTC..AA.......TA.GGC...A...AC.TTGTTAA.TTC.TC.TGTCCC..G.....A.GT.A.AGGCC...T.ACAG...TGGT..GGA.A.AA..T.TT....A.CCA...CA.AA.TG.ATG..CAT.A..TTTTAA.A...T.CGAA.T.G..C.TGTTTCC...A.A..A.AAG.T.GA..G.CA.AT.TAA..CT.T.TAA.......G...TAC.G.T...AGC.T      538    538 ,    538    538     111:>gi436409289gbKC242786.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/2007/1 Luebo, complete genome                     
 112 >gi436409429gbKC242800.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/GAB/2002/Ilembe, complete genome                      C.C.A.AA...T..ACG.A..C.T..T.T.TT.GG.......A...CAA...T....CG..T..T.A.A...TA.AC...T..........GT.AG.A...T......G.T.C.C....TAT...GC....C.T..G..C..G.C....TC..ATG.AG..C....T...G.T...T.......C...T.....AG.A..........AC....CCT.A.G...CC.G.C....G...AT.T.C...C...T.....T..T....A..CG.CA..........T..A....AG.TG.T...T..A.T.C....T.T...C...T...AAG..C.CT.....CT..A..A..ACC....A.CA..G......CC...C...A....G...C.G....TC.C.....ACA.....CCC......C.T..C.C.A.C...G..T.GT...ACTTC.....CTC.T.GGT.G.T..T..T.G...GCGGGGCT.CG.T....TG..A.AAAG..A.G.........GA...GCTG.T.T.T..C..C.........TGA.G..CA.GGAT....TC.AT.....G..........C...GA.T......T...GC.....T.T.AGT.CG..CG....GT..A..TT......G.C...TG.C.G...TA....AA.C....G..C......G..A..A..G.C..T.T.TCCA...G...A.T.A.T...T.G..A..CA.T.......G..T..A....GCA..CA.A......C....G.T.GC.....C....C...G.AATGC.C..AA........A.GGC...A...AC.T.GT.AA.T.C..C.TGTC.C..G.......GT...A.GCC.....A..G...TGG...G.A.A.A...T.T....G..C.....C......G.AT.....T.A..TTTTA..A...T.C.AA.T.G..C..GTT.CC...AGA..A..A..T..A..G.CA..T..AA..CT.T.TAA.........-.TA..G.....AGC.T      601    390 ,    600    389     112:>gi436409429gbKC242800.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/GAB/2002/Ilembe, complete genome                      
 113 >gi566573369gbKF827427.1, Mutant Zaire ebolavirus, complete sequence                                                       C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC....TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CGT.TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG......TCT.A.T.CG..CG.T..GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.AGC.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      562    560 ,    562    560     113:>gi566573369gbKF827427.1, Mutant Zaire ebolavirus, complete sequence                                                       
 114 >gi23630482gbAY142960.1, Zaire Ebola virus strain Mayinga subtype Zaire, complete genome                                   C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC....TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CG..TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG......TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      559    559 ,    559    559     114:>gi23630482gbAY142960.1, Zaire Ebola virus strain Mayinga subtype Zaire, complete genome                                   
 115 >gi436409339gbKC242791.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/1977/Bonduni, complete genome                     C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC....TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.......C.AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CG..TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG......TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      560    560 ,    560    560     115:>gi436409339gbKC242791.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/1977/Bonduni, complete genome                     
 116 >gi298226048,emb,HC874665.1, Sequence 11 from Patent WO2010053573                                                          C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.AGG.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC..C.TCATATGGAGCCC.GA.T...G.TTCAT.......C...T.....AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.......C.AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC...CA.CA..GT.....TC...C.CAAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CG..TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTGGT.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG.T....TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....CC...C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GTG..A.GCCGTT..A..GA.ATGG...G.A.A.A.C.TGT..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      568    568 ,    568    568     116:>gi298226048,emb,HC874665.1, Sequence 11 from Patent WO2010053573                                                          
 117 >gi269841403,emb,HC069221.1, Sequence 12 from Patent WO2009128867                                                          C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.AGG.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC..C.TCATATGGAGCCC.GA.T...G.TTCAT.......C...T.....AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.......C.AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC...CA.CA..GT.....TC...C.CAAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CG..TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTGGT.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG.T....TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....CC...C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GTG..A.GCCGTT..A..GA.ATGG...G.A.A.A.C.TGT..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      568    568 ,    568    568     117:>gi269841403,emb,HC069221.1, Sequence 12 from Patent WO2009128867                                                          
 118 >gi21702647gbAF499101.1, Zaire Ebola virus strain Mayinga, complete genome                                                 C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.AGG.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC..C.TCATATGGAGCCC.GA.T...G.TTCAT.......C...T.....AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.......C.AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC...CA.CA..GT.....TC...C.CAAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CG..TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTGGT.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG.T....TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....CC...C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GTG..A.GCCGTT..A..GA.ATGG...G.A.A.A.C.TGT..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      568    568 ,    568    568     118:>gi21702647gbAF499101.1, Zaire Ebola virus strain Mayinga, complete genome                                                 
 119 >gi269841401,emb,HC069217.1, Sequence 7 from Patent WO2009128867                                                           C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC....TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CG..TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG......TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      559    559 ,    559    559     119:>gi269841401,emb,HC069217.1, Sequence 7 from Patent WO2009128867                                                           
 120 >gi436409439gbKC242801.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/1976/deRoover, complete genome                    C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC....TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CG..TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG......TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      560    559 ,    560    559     120:>gi436409439gbKC242801.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/1976/deRoover, complete genome                    
 121 >gi298226046,emb,HC874661.1, Sequence 7 from Patent WO2010053573                                                           C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC....TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CG..TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG......TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      559    559 ,    559    559     121:>gi298226046,emb,HC874661.1, Sequence 7 from Patent WO2010053573                                                           
 122 >gi347641082,emb,JA489037.1, Sequence 20 from Patent EP2350270                                                             C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC....TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CGT.TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG......TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      560    560 ,    560    560     122:>gi347641082,emb,JA489037.1, Sequence 20 from Patent EP2350270                                                             
 123 >gi298226054,emb,HC874677.1, Sequence 23 from Patent WO2010053573                                                          C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC....TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CGT.TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG......TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      560    560 ,    560    560     123:>gi298226054,emb,HC874677.1, Sequence 23 from Patent WO2010053573                                                          
 124 >gi269841409,emb,HC069235.1, Sequence 26 from Patent WO2009128867                                                          C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC....TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CGT.TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG......TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      560    560 ,    560    560     124:>gi269841409,emb,HC069235.1, Sequence 26 from Patent WO2009128867                                                          
 125 >gi10141003gbAF086833.2, Ebola virus - Mayinga, Zaire, 1976, complete genome                                               C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC....TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CGT.TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG......TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      560    560 ,    560    560     125:>gi10141003gbAF086833.2, Ebola virus - Mayinga, Zaire, 1976, complete genome                                               
 126 >gi10313991,ref,NC_002549.1, Zaire ebolavirus isolate Ebola virus H.sapiens-tc/COD/1976/Yambuku-Mayinga, complete genome   C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC....TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CGT.TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG......TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      560    560 ,    560    560     126:>gi10313991,ref,NC_002549.1, Zaire ebolavirus isolate Ebola virus H.sapiens-tc/COD/1976/Yambuku-Mayinga, complete genome   
 127 >gi269841411,emb,HC069239.1, Sequence 30 from Patent WO2009128867                                                          C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC....TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CGT.TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG......TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      560    560 ,    560    560     127:>gi269841411,emb,HC069239.1, Sequence 30 from Patent WO2009128867                                                          
 128 >gi298226056,emb,HC874681.1, Sequence 27 from Patent WO2010053573                                                          C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.GTT.CAC..G.TAT...G..G..C.T.CG..C..GTC....TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CGT.TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG......TCT.A.T.CG..CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      560    560 ,    560    560     128:>gi298226056,emb,HC874681.1, Sequence 27 from Patent WO2010053573                                                          
 129 >gi298226057,emb,HC874683.1, Sequence 29 from Patent WO2010053573                                                          C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GTTAG.A...TT..GTTGTT.CAC..G.TAT...G..G..C.T.CG..C..GTCCC..TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CGT.TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.A.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG.....ATCT.A.T.CGC.CGTTA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A....G.C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      568    568 ,    568    568     129:>gi298226057,emb,HC874683.1, Sequence 29 from Patent WO2010053573                                                          
 130 >gi269841412,emb,HC069241.1, Sequence 32 from Patent WO2009128867                                                          C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GTTAG.A...TT..GTTGTT.CAC..G.TAT...G..G..C.T.CG..C..GTCCC..TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CGT.TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.A.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG.....ATCT.A.T.CGC.CGTTA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A....G.C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      568    568 ,    568    568     130:>gi269841412,emb,HC069241.1, Sequence 32 from Patent WO2009128867                                                          
 131 >gi11761745gbAF272001.1, Zaire Ebola virus strain Mayinga, complete genome                                                 C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GTTAG.A...TT..GTTGTT.CAC..G.TAT...G..G..C.T.CG..C..GTCCC..TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...T..A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CGT.TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.A.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG.....ATCT.A.T.CGC.CGTTA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A....G.C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CTG..C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      568    568 ,    568    568     131:>gi11761745gbAF272001.1, Zaire Ebola virus strain Mayinga, complete genome                                                 
 132 >gi297340571gbEU224440.2, Zaire ebolavirus strain Mayinga, complete genome                                                 C.C.A.AA..CT..ACG.A..CGT.TTGTATT.GA.AG..A.A.G.CAAA..T...CCG.CT..T.A.AT.AT..AC...T.....G....GT.AG.A...TT..GT.ATT.CAC.CG.TA..CCGC.G.CC.T.CG..C..GTC....TCATATGGAGCCC.GA.T...G.TTCAT.......C...T...C.AG...C.......C.C.A..CCT.A..G..CC.GAC..G.G..TAT.T.C.GG....TAG..C...T..C.AT..G.CA.........AT..A..T.AGCTGCT...TC.A.T..G..AT.T..TCG..T.A.AAG..C.CT...G.CTG.ACGAC.ACC....A.CA..GT.....TC...C..AAT.T.G..GC.GA..CTCTC.....ACA..TT.CCC..A..TCAT.CC.C.A.CT.CGT.TAGT...ACTTC.C...CTC.TAGG.CGTT..T..TCGA..GCGGGGCT.CG.TA...TGG.A.AAAG..A.G..T......GAGGCGCTG.T.T.T..C.CC....A..CGTGA.G..TA.GGATG...TC.ATC....GA......TT.C...GA.T...T..T.CGG.....ATCT.A.T.CGC.CG.TA.GTGAA..TT...C..G.C..TTG.CAGC.TTACA.TAA.CGCGGGA.C.T...AG.TA..A.CG.C.AT.T.TCCAT.AG...A.T.ACTC..T.G.GAC.CATT.A.C.C.G..TA.A.A.GGCA.TCA.A......C....G.TTGC.....C....C.CCG.AATGC.C..AAC..TTAT.AAGGC...A...AC.T.GT.AA.T.CG.CTTGTC.CA.G....T..GT...A.GCCGTT..A..GA.ATGG...G.A.A.A.C.T.T..CT...C.....C....A.GCAT..A.AT.AT.TTTTA..AATGT.C.AAAT.G.CC..GTT.CC.CTA.ACCA....CTT.A..G.CAT.T..AA..CT.TATAA.T.C....C..TA..GG....AGC.T      576    566 ,    576    566     132:>gi297340571gbEU224440.2, Zaire ebolavirus strain Mayinga, complete genome                                                 
 133 >gi436409399gbKC242797.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/GAB/1996/1Oba, complete genome                        C.C.ATAA.G.T..ACG.A..CGT.TT.T.TTGGG......GA.GGCAAAC.T....CGC.T..T.AAAT.AT.CAC.T.TAGG..G....GT.AG.ATATTT.....G.TACACA...TA....G.A..CCTT..GG.C..G.C....TCATATG.AGCCC.GA.T...G.T.CAT....AA.C...TCACC.AG...CT.A....C.C....CCT.A..G..CC.G.C..G.GCTTAT.T.C.G.CG..TAG..C...T...TA.ACG.CA.C.GGT...ATTGA....AGCTG.TAG.T..A.TG..AGAT.TG..C...T...AAGTCC.C.CCAGTCT..A.GA..ACCGCG.A.CAA.G....G.TC..CCT.AAT..AG..GC.G..T..C.C..C..ACACA...C.CG.A.CTCAT.CC.C.A.CT.CG.GTAGTA.CACTTC..TGGCTCGT.GG.CGTT.ATTTTCGAAAGCGGGGCTACGGTA...TGGAATAAAG.GA.G.G..CGTG.GAGG.GCTG...T.TCCC..C........GTTA.GG.TA.GGAT.CCTTC.ATCG...G....TAG.T.C.T.GA.T.AG..GTACGG......TCT.A.TACG..CG..A.GT..A..TT..T..CGTCCTTTGTCAGCGTTACAGTAA.CGCG.G.GCCTC...GGTAT.A.CGACGAT.TATCCA.AAG...A.T.ACTCCGT.G..A..CATTA.TC.CGGG.TATACAT.GCAC.CATA.T...ACCGT.GATTGC.T.A.C.G..C.CCG.AATGC.C.CAA....TAT.GAGGCGCTAGGTACCT.GT.AA.T.C..C.T.TC.CACGC......GT..TA.GCC.TT.GA..GAA.TGG..AG.ATAGA.C.T.T..C.G.GC..G..C......G.AT.AA..TCA..TTTTA.AA.T.T.C.AAATAG.CCG.GTT.CCCC.AC..CA....CT..AT.G.CAT.T..AAA.CT.T.TAA.....AC....TA.GGG.T..AGCAT      644    644 ,    644    644     133:>gi436409399gbKC242797.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/GAB/1996/1Oba, complete genome                        
 134 >gi436409359gbKC242793.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/GAB/1996/1Eko, complete genome                        C.C.ATAA.G.T..ACG.A..CGT.TT.T.TTGGG......GA.GGCAAAC.T....CGC.T..T.AAAT.AT.CAC.T.TAGG..G....GT.AG.ATATTT.....G.TACACA...TA....G.A..CCTT..GG.C..G.C....TCATATG.AGCCC.GA.T...G.T.CAT....AA.C...TCACC.AG...CT.A....C.C....CCT.A..G..CC.G.C..G.GCTTAT.T.C.G.CG..TAG..C...T...TA.ACG.CA.C.GGT...ATTGA....AGCTG.TAG.T..A.TG..AGAT.TG..C...T...AAGTCC.C.CCAGTCT..A.GA..ACCGCG.A.CAA.G....G.TC..CCT.AAT..AG..GC.G..T..C.C..C..ACACA...C.CG.A.CTCAT.CC.C.A.CT.CG.GTAGTA.CACTTC..TGGCTCGT.GG.CGTT.ATTTTCGAAAGCGGGGCTACGGTA...TGGAATAAAG.GA.G.G..CGTG.GAGG.GCTG...T.TCCC..C........GTTA.GG.TA.GGAT.CCTTC.ATCG...G....TAG.T.C.T.GA.T.AG..GTACGG......TCT.A.TACG..CG..A.GT..A..TT..T..CGTCCTTTGTCAGCGTTACAGTAA.CGCG.G.GCCTC...GGTAT.A.CGACGAT.TATCCA.AAG...A.T.ACTCCGT.G..A..CATTA.TC.CGGG.TATACAT.GCAC.CATA.T...ACCGT.GATTGC.T.A.C.G..C.CCG.AATGC.C.CAA....TAT.GAGGCGCTAGGTACCT.GT.AA.T.C..C.T.TC.CACGC......GT..TA.GCC.TT.GA..GAA.TGG..AG.ATAGA.C.T.T..C.G.GC..G..C......G.AT.AA..TCA..TTTTA.AA.T.T.C.AAATAG.CCG.GTT.CCCC.AC..CA....CT..AT.G.CAT.T..AAA.CT.T.TAA.....AC....TA.GGG.T..AGCAT      644    644 ,    644    644     134:>gi436409359gbKC242793.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/GAB/1996/1Eko, complete genome                        
 135 >gi436409379gbKC242795.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/GAB/1996/1Mbie, complete genome                       C.C.ATAA.G.T..ACG.A..CGT.TT.T.TTGGG......GA.GGCAAAC.T....CGC.T..T.AAAT.AT.CAC.T.TAGG..G....GT.AG.ATATTT.....G.TACACA...TA....G.A..CCTT..GG.C..G.C....TCATATG.AGCCC.GA.T...G.T.CAT....AA.C...TCACC.AG...CT.A....C.C....CCT.A..G..CC.G.C..G.GCTTAT.T.C.G.CG..TAG..C...T...TA.ACG.CA.C.GGT...ATTGA....AGCTG.TAG.T..A.TG..AGAT.TG..C...T...AAGTCC.C.CCAGTCT..A.GA..ACCGCG.A.CAA.G....G.TC..CCT.AAT..AG..GC.G..T..C.C..C..ACACA...C.CG.A.CTCAT.CC.C.A.CT.CG.GTAGTA.CACTTC..TGGCTCGT.GG.CGTT.ATTTTCGAAAGCGGGGCTACGGTA...TGGAATAAAG.GA.G.G..CGTG.GAGG.GCTG...T.TCCC..C........GTTA.GG.TA.GGAT.CCTTC.ATCG...G....TAG.T.C.T.GA.T.AG..GTACGG......TCT.A.TACG..CG..A.GT..A..TT..T..CGTCCTTTGTCAGCGTTACAGTAA.CGCG.G.GCCTC...GGTAT.A.CGACGAT.TATCCA.AAG...A.T.ACTCCGT.G..A..CATTA.TC.CGGG.TATACAT.GCAC.CATA.T...ACCGT.GATTGC.T.A.C.G..C.CCG.AATGC.C.CAA....TAT.GAGGCGCTAGGTACCT.GT.AA.T.C..C.T.TC.CACGC......GT..TA.GCC.TT.GA..GAA.TGG..AG.ATAGA.C.T.T..C.G.GC..G..C......G.AT.AA..TCA..TTTTA.AA.T.T.C.AAATAG.CCG.GTT.CCCC.AC..CA....CT..AT.G.CAT.T..AAA.CT.T.TAA.....AC....TA.GGG.T..AGCAT      644    644 ,    644    644     135:>gi436409379gbKC242795.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/GAB/1996/1Mbie, complete genome                       
 136 >gi436409349gbKC242792.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/GAB/1994/Gabon, complete genome                       C.C.ATAA...T..ACG.A..CGT.TT.T.TTGGG......GA.GGCAAAC.T....CGC.T..T.AAAT.AT.CAC.T.TAGG..G....GT.AG.A.ATTT.....G.TACACA...TA....G....CCTT..GG.C..G.C....TCATATG.AGCCC.GA.T...G.T.CAT....AA.C...TCACC.AG...CT.A....C.C....CCT.A..G..CC.G.C..G.GCTTAT.T.C.G.C...TAG..C...T...TA.ACG.CA.C.GGT.A.ATTGA....AGCTG.TAG.T..A.TG..AGAT.T...C...T...AAGTCC.C.CCAGTCT..A.GA..ACCGCG.A.CAA.G....G.TC..CCT.AAT..AG..GC.G..T..C.C..C..ACACA...C.CG.A.CTCAT.CC.C.A.CT.CG.GTAGTA.CACTTC..TGGCTC.T.GG.CGTT..TTTTCGAAAGCGGGGCTACGGTA...TGGAATAAAG.GA.G.G....TG.GAGG.GCTG...T.TCCC..C........GTTA.GG.TA.GGAT.CCTTC.ATCG...G....TAG.T.C.T.GA.T.AG...TACGG......TCT.A.TACG..CG..A.GT..A..TT..T..CG.CCTTTGTCAGCGTTACAGTAA.CGCG.G.GCCTC...G.TAT.A.CGACGAT.TATCCA..AG...A.T.ACTCCGT.G..A..CATT..TC.CGGG.TATACA..GCAC.CATA.T...ACCGT.GATTGC.T.A.C.G..C.CCG.AATGC.C.CAA....TAT.AAGGCGCTAGGTAC.T.GT.AA.T.C..C.T.TC.CACGC......GT..TA.GCC.TT.GA..GAA.TGG..AG.ATA.A.C.T.T..C.G.GC..G..C......G.AT.AA..TCA..TTTTA.AA.T.T.C.AAATAG.CCG.GTT.CC.C.AC..CA....CT..AT.G.CAT.T..AAA.CT.T.TAA.....A.....TA.GGG.T..AGCAT      640    626 ,    640    626     136:>gi436409349gbKC242792.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/GAB/1994/Gabon, complete genome                       
 137 >gi436409409gbKC242798.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/GAB/1996/1Ikot, complete genome                       C.C.ATAA...T..ACG.A..CGT.TT.T.TTGGG......GA.GGCAAA..T....CGC.TG.T.AAAT.AT.CAC.T.T..GC.G....GT.AG.A..TTT.....G.T.CACA...TA....G...GCCTT..GG.C..G.C....TCCTATG.AGCCC.GATTCC.G.T.CAT....AATC...TCACC.AGG..CTGA..C.C.C....CCT.A..G..CCGG.C.TG.GCTTAT.T.C.G.C...TAG..C.TTT...TA.ACG.CA.C.GGT...ATTGA....AGCTG.TA..T..A.TG..AGAT.T...C...T...AAGTCC.C.CCAGTCT..A.GA..ACCGCG.A.CAA.G....GTTCA.CCT.AAT..AG..GC.G.CT..C.C..C..ACACA...C.CG.A.CTCAT.CCAC.A.CT.CG.GTAGTA.CACTTC..TGGCTC.T.GG.CGTTG.TTTTCGAAAGCGGGGCTACGGTACCCTGGAATAAAG.GA.G......TGCGAGGCGCTG...T.TC....C.....C..GTTA.GG.TA.GGAT.CCTTC.ATCG...G....TAG.T.C.T.GA.T.AG...TACGG......TCT.AGTACG..CG..A.GT..A..TT.....CG.CCTTTGTCAGCGTTACAGTAA.CGCG.G.GCCTC...G.TAT.A.CGACGAT.TATCCA..AG...AGT.ACTCCGT.G..A..CATT..TC.CGGGGTATACA..GCAC.CATA.T...ACCGT.GATTGC.T.A.C.G..C.CCG.AATGC.C..AA..C.TAT.AAGGCGCTAGGTAC.T.GT.AACT.C..C.T.TC.CACGCC....TGT..TA.GCC.TT.GA..GAA.TGG..AG.ATA.A.C.T.T.GC.G..C..G..C.G....G.AT.AA..TCA..TTTTA.AA.TCT.C.AAATAGCCCG.GTT.CC.C.AC..CAC...CT..AT.G.CAT.TG.AAA.CT.T.TAA.....A...C.TA.GGG.TC.A.CAT      652    652 ,    652    652     137:>gi436409409gbKC242798.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/GAB/1996/1Ikot, complete genome                       
 138 >gi436409369gbKC242794.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/GAB/1996/2Nza, complete genome                        C.C.ATAA...T..ACG.A..CGT.TT.T.TTGGG......GA.GGCAAA..T....CGC.TG.T.AAAT.AT.CAC.T.T..GC.G....GT.AG.A..TTT.....G.T.CACA...TA....G...GCCTT..GG.C..G.C....TCCTATG.AGCCC.GATTCC.G.T.CAT....AATC...TCACC.AGG..CTGA..C.C.C....CCT.A..G..CCGG.C.TG.GCTTAT.T.C.G.C...TAG..C.TTT...TA.ACG.CA.C.GGT...ATTGA....AGCTG.TA..T..A.TG..AGAT.T...C...T...AAGTCC.C.CCAGTCT..A.GA..ACCGCG.A.CAA.G....GTTCA.CCT.AAT..AG..GC.G.CT..C.C..C..ACACA...C.CG.A.CTCAT.CCAC.A.CT.CG.GTAGTA.CACTTC..TGGCTC.T.GG.CGTTG.TTTTCGAAAGCGGGGCTACGGTACCCTGGAATAAAG.GA.G......TGCGAGGCGCTG...T.TC....C.....C..GTTA.GG.TA.GGAT.CCTTC.ATCG...G....TAG.T.C.T.GA.T.AG...TACGG......TCT.AGTACG..CG..A.GT..A..TT.....CG.CCTTTGTCAGCGTTACAGTAA.CGCG.G.GCCTC...G.TAT.A.CGACGAT.TATCCA..AG...AGT.ACTCCGT.G..A..CATT..TC.CGGGGTATACA..GCAC.CATA.T...ACCGT.GATTGC.T.A.C.G..C.CCG.AATGC.C..AA..C.TAT.AAGGCGCTAGGTAC.T.GT.AACT.C..C.T.TC.CACGCC....TGT..TA.GCC.TT.GA..GAA.TGG..AG.ATA.A.C.T.T.GC.G..C..G..C.G....G.AT.AA..TCA..TTTTA.AA.TCT.C.AAATAGCCCG.GTT.CC.C.AC..CAC...CT..AT.G.CAT.TG.AAA.CT.T.TAA.....A...C.TA.GGG.TC.A.CAT      652    652 ,    652    652     138:>gi436409369gbKC242794.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/GAB/1996/2Nza, complete genome                        
 139 >gi33860540gbAY354458.1, Zaire ebolavirus strain Zaire 1995, complete genome                                               C.C.ATAA...T.CACG.A..CGTTTT.T.TT.GAC.....GA.G.CAAA..TT...CGC.T.CT.AAAT.AT.CAC...T..G..G.AATGT.AG.A..TTTA....G.T.CAC...TTA...CGC....C.TG.G..C..G.C....TCATATG.AGCCCGGA.T..CG.T.CAT....AA.CC..TC.CC.AG.C.C..ATT..CAC....CCT.A..GCTCC.G.C..G.G.TTATGT.CCG...A.TAG..C...T.A..A..CG.CA.CG.GT...ATTGA....AGCTG.T...TC.A.T.....ATCT.A.C...T...AAG.CC.C.C.AG.CT..A.GA..ACCGC..A.CA..G.C....TC.A.CT.AAT..AG..GC.G.....C.C..C..ACA.....CCCGTACCTCAT.CC.CGAGCT.CG.GTAGT..CACTTC.....CTC.T.GG.CGTT..TTTTCGA..GCGGGGCTACG.TA...TGG.ATAAAG..ATGT.....TG.GAGGCGCTG...T.TC.C..CC.......GTGA.GGTTA.GGAT..C.TC.AT...A.G........T.C.T.GA.T..G.C.T.CGG...A..TCT.A.TACG.GCG..AAGT..A..TTG....CG.C.TTTG.CAGT.TTACAGTAA.CGCG.G..C.T....G.TAT.A.CG.C.AT.T.TCCA..AG...AGT.ACTC.GT.G..A...ATT...C.C.G..TA.A.A..GCA..CA.A.T...AC....G.TTGC.T.A....A.C.CCG.AATGC.CG.AA.G..TAT.AAGTC.CTAG..AC.T.GT.AA.T.C..C.T.TC.CA.G..G....GT..TA.GCC.TT..A.AGA..TGG.A.G.ATA.A.CTT.T..C.G..C...TGC......G.AT..A..TCA.CTTTTA.AA.T.T.C.AAATAG.CC..GTT.CC.C.A...CA....CT..A..GACAT.T..AAAGCT.T.TAAA.G.A.....TTA..GG.T.TAGCAT      596    595 ,    596    595     139:>gi33860540gbAY354458.1, Zaire ebolavirus strain Zaire 1995, complete genome                                               
 140 >gi384406804gbJQ352763.1, Zaire ebolavirus strain Kikwit, complete genome                                                  C.C.ATAA...T.CACG.A..CGTTTT.T.TT.GAC.....GA.G.CAAA..TT...CGC.T.CT.AAAT.AT.CAC...T..G..G.AATGT.AG.A..TTTA....G.T.CAC...TTA...CGC....C.TG.G..C..G.C....TCATATG.AGCCCGGA.T..CG.T.CAT....AA.CC..TC.CC.AG.C.C..ATT..CAC....CCT.A..GCTCC.G.C..G.G.TTATGT.CCG...A.TAG..C...T.A..A..CG.CA.CG.GT...ATTGA....AGCTG.T...TC.A.T.....ATCT.A.C...T...AAG.CC.C.C.AG.CT..A.GA..ACCGC..A.CA..G.C....TC.A.CT.AAT..AG..GC.G.....C.C..C..ACA.....C.CGTACCTCAT.CC.CGAGCT.CG.GTAGT..CACTTC.....CTC.T.GG.CGTT..TTTTCGA..GCGGGGCTACG.TA...TGG.ATAAAG..ATGT.....TG.GAGGCGCTG...T.TC.C..CC.......GTGA.GGTTA.GGAT..C.TC.AT...A.G........T.C.T.GA.T..G.C.T.CGG...A..TCT.A.TACG.GCG..AAGT..A..TTG....CG.C.TTTG.CAGT.TTACAGTAA.CGCG.G..C.T....G.TAT.A.CG.C.AT.T.TCCA..AG...AGT.ACTC.GT.G..A...ATT...C.C.G..TA.A.A..GCA..CA.A.T...AC....G.TTGC.T.A....A.C.CCG.AATGC.CG.AA.G..TAT.AAGTC.CTAG..AC.T.GT.AA.T.C..C.T.TC.CA.G..G....GT..TA.GCC.TT..A.AGA..TGG.A.G.ATA.A.CTT.T..C.G..C...TGC......G.AT..A..TCA.CTTTTA.AA.T.T.C.AAATAG.CC..GTT.CC.C.A...CA....CT..A..GACAT.T..AAAGCT.T.TAAA.G.A.....TTA..GG.T.TAGCAT      598    594 ,    598    594     140:>gi384406804gbJQ352763.1, Zaire ebolavirus strain Kikwit, complete genome                                                  
 141 >gi436409419gbKC242799.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/1995/13709 Kikwit, complete genome                C.C.ATAA...T.CACG.A..CGTTTT.T.TT.GAC.....GA.G.CAAA..TT...CGC.T.CT.AAAT.AT.CAC...T..G..G.AATGT.AG.A..TTTA....G.T.CAC...TTA...CGC....C.TG.G..C..G.C....TCATATG.AGCCCGGA.T..CG.T.CAT....AA.CC..TC.CC.AG.C.C..ATT..CAC....CCT.A..GCTCC.G.C..G.G.TTATGT.CCG...A.TAG..C...T.A..A..CG.CA.CG.GT...ATTGA....AGCTG.T...TC.A.T.....ATCT.A.C...T...AAG.CC.C.C.AG.CT..A.GA..ACCGC..A.CA..G.C....TC.A.CT.AAT..AG..GC.G.....C.C..C..ACA.....C.CGTACCTCAT.CC.CGAGCT.CG.GTAGT..CACTTC.....CTC.T.GG.CGTT..TTTTCGA..GCGGGGCTACG.TA...TGG.ATAAAG..ATGT.....TG.GAGGCGCTG...T.TC.C..CC.......GTGA.GGTTA.GGAT..C.TC.AT.....G........T.C.T.GA.T..G...T.CGG...A..TCT.A.TACG..CG..AAGT..A..TTG....CG.C.TTTG.CAGT.TTACAGTAA.CGCG.G..C.T....G.TAT.A.CG.C.ATCT.TCCA..AG...AGT.ACTC.GT.G..A...ATT...CGC.G..TA.A.A..GCA..CA.A.T...AC....G.TTGC.T.A....A.C.CCGAAATGC.CG.AA.G..TAT.AAGTC.CTAG..AC.T.GT.AA.T.C..C.T.TC.CA.G..G....GT..TA.GCC.TT..A.AGA..TGG.A.G.ATA.A.C.T.T..C.G..C...TGC......G.AT..A..TCA.CTTTTA.AA.T.T.C.AAATAG.CC..GTT.CC.C.A...CA....CT..A..GACAT.T..AAAGCT.T.TAAA.G.A.....TTA..GG.T.TAGCAT      593    593 ,    593    593     141:>gi436409419gbKC242799.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/1995/13709 Kikwit, complete genome                
 142 >gi436409389gbKC242796.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/1995/13625 Kikwit, complete genome                C.C.ATAA...T.CACG.A..CGTTTT.T.TT.GAC.....GA.G.CAAA..TT...CGC.T.CT.AAAT.AT.CAC...T..G..G.AATGT.AG.A..TTTA....G.T.CAC...TTA...CGC....C.TG.G..C..G.C....TCATATG.AGCCCGGA.T..CG.T.CAT....AA.CC..TC.CC.AG.C.C..ATT..CAC....CCT.A..GCTCC.G.C..G.G.TTATGT.CCG...A.TAG..C...T.A..A..CG.CA.CG.GT...ATTGA....AGCTG.T...TC.A.T.....ATCT.A.C...T...AAG.CC.C.C.AG.CT..A.GA..ACCGC..A.CA..G.C....TC.A.CT.AAT..AG..GC.G.....C.C..C..ACA.....C.CGTACCTCAT.CC.CGAGCT.CG.GTAGT..CACTTC.....CTC.T.GG.CGTT..TTTTCGA..GCGGGGCTACG.TA...TGG.ATAAAG..ATGT.....TG.GAGGCGCTG...T.TC.C..CC.......GTGA.GGTTA.GGAT..C.TC.AT.....G........T.C.T.GA.T..G...T.CGG...A..TCT.A.TACG..CG..AAGT..A..TTG....CG.C.TTTG.CAGT.TTACAGTAA.CGCG.G..C.T....G.TAT.A.CG.C.ATCT.TCCA..AG...AGT.ACTC.GT.G..A...ATT...CGC.G..TA.A.A..GCA..CA.A.T...AC....G.TTGC.T.A....A.C.CCGAAATGC.CG.AA.G..TAT.AAGTC.CTAG..AC.T.GT.AA.T.C..C.T.TC.CA.G..G....GT..TA.GCC.TT..A.AGA..TGG.A.G.ATA.A.C.T.T..C.G..C...TGC......G.AT..A..TCA.CTTTTA.AA.T.T.C.AAATAG.CC..GTT.CC.C.A...CA....CT..A..GACAT.T..AAAGCT.T.TAAA.G.A.....TTA..GG.T.TAGCAT      594    593 ,    594    593     142:>gi436409389gbKC242796.1, Zaire ebolavirus isolate EBOV/H.sapiens-tc/COD/1995/13625 Kikwit, complete genome                
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
---Index------------------------------------------------------------------------------------------------------------------------TGTACCGGAATCATGTAACGTTACCCCACGCCAATAGAGCGATAAATGGGTTCCATTTATTCAACTGGCCTGAGTGTTCAGGAATTACGGCACCGACGCGCCCGGACCCCCGAGTCTTCCCCATTATTAATTCCATAATTAGACTTTTGCTGCTCAAGTTTTAACCGTTTAGGCTGCCCCTGGCATCGCTGTTAGAAGGTCAGCATTTGTAGAATTCTGGAAACTTAACTTCAGATACTGACCTTAATAGTCGAGGTCCGCCTTCGCGTACTTTTATACGTCTCGAGTTCATATCATCTAACTCGGCTTAGAGCTCACCTACACGGGGGAGATATCTTGACTGAAGTAGTTGTTATATGCTGGGACTCATCGTGGTTCTGGCGCGCAGAAAAGTCTCTCACCTGTGTGAGCCCTTTACGTTCTGCATTGAAGATCTTACACGACGCTGACCTCTCAATCTCCCAACTACCAGCCCCAAGGGAAAAAATCGACACCTTTCAACCACCGATAGCACACAAACATAGAATATATACCCGGTTTATTTACTCTGTCACGGTACAGCAAGCATTCCTCGGTAGGAATACGCGACCTTGAAAGTAAGACAACGTAATCCTAGCACCTACGTATATACAGGACAGGGAACTCCTGTTCTTCAGACTGAAACCGTCACTGGAATAAAGATTCTTGCATCGCACATAGTAGCTCGCTTGCGGAACTCAAACTCATACGAAAGTCTGCCGGCTTTAAAACGCGAGCAATGTCTGCGCCCTAGTTACTAGCCATCCAGTTTAGCTGTTATGCCAACTAAGGTATCAGGCCTAATAAAGAACGTTCAAGCGGACCTACTCCACTTTGTATTATCCCACAGCGAATTTCCCACTTAGGGGAACGGAAGCGAGGAGCTCCAACAGATTCACATGAGCGCATGCAGGTGCTGCTCCGCGGTGGCTCCTAGGGCGATTTTCACACTTTTCCTGTTGTGGATCCAGGTACTGCGCTCTGGATCACGCGGGAATGCTATTCCTTAATCGTCGATGC 
-codon-position-----------------------------------------------------------------------------------------------------------------112 2 211222222 2 1122  22  11212121221 11121 21 11111112111121111111111111111111 111111111111211 121111 1    122 111111111121111 1111 11 1   121121111111211 22  2 2112   212  22222 12 221 2 21121222122222222221 2222222222 2 111 1  1221 2 1122 121 22212222221222222222222222222221222222 212  2 21 2   12 1 22 11222212  211121111 2  1 22 2112 2  112 22222222 22122222222222212222  2221    11  2112 21 2 22112 1  21 12 2 2 11221 2 222 122 2122222222222 22 22221  22 2121112 1122  1 12    22121   1212111211211111111121 1211112112211  121111  221 12212 2 21  1211  2 2  12121 2121 221  1212112  111   22 2 122222221 222222222 2 2112211222221221  121  1 1  2 122121211  2 222222222 22222 22222 2222  2 222 2 22222222222 2222222222221222222222222222222 222222212 222221222222 222222222222222222 12 222222222222 1 22221222  222222 22222222222222222121222212222222222 22222 22222 222  12 21222   2 1 1122 222 222 1 121222 222222222212222 122   222 2222222222 22 2222222222222 2 11 12   1 1 1  1222 1 1 2121   21112121112 1 1  11121221111 2 11 2  
                                                                                                                                000000000000000000000000000000000000000000000000000000111111111111111111111111111111111111111111111111111122222222222222222222222222222222222222222222222222222222222222222222222222223333333333333333333333333333333333334444444444444444444444444444444444444444444444444444455555555555555555555555555555555555555555555555555555555555555555555555556666666666666666666666666666666666666666666777777777777777777777777777777777777777777777777777777777777777777777788888888888888888888888888888888888888888888888899999999999999999999999999999999999999999999999999999999999990000000000000000000000000000000000000000000000000000000000000000001111111111111111111111111111111111111111111111111111111111222222222222222222222222222222222222222222223333333333333333333333333333333333344444444444444444444444444444444444444444444444555555555555555555555555555555555555555556666666666666666666666666666666666666666666666666666666666666666666777777777777777777777777777777777777888888888888888888888888888888888888888888888888888888888888888888888888888888 
                                                                                                                                111111111222222222233333333333344444455566667788889999000111112233444444555555666666667788888888899999999900000000000011111222222222233333333333444444555566666777777788888999999999990000111111112233333334555667778889990000111111122222222333333333444455566666667788889999900000111122233444445555555555555566666666667777777777788888888889999999990000000111112222223445555566667777788889999000011111111122222222223333333333333333444555555566666777777778888888900000001111111112222233333334444444455666777999900000001122344444455555555555566666677777777777778888889999990000000000001111111111111222222222233333444444455555566666667888990000111111122333333333334444444444556666677778888889999999001111222233333444455555566666778888888888990001111122233444445566666788888899900011111111222222333344455556666666677778888999000001111113333344455566666777777788888990000001111222233333334444445555555556666677777777778888889999999999000012233344444455555666777788888899000111222222223333333333333333444444444445555555556666666666777777777778888888 
                                                                                                                                234558889133555666912566777888901236904912582205590117299045993407124579014459014668990601344567901145678914445567889902567022334566612344566789011246138913459011335915568012233378880589112345673511235993037260335890465677566678814455799011244568133903612346780313671247726799145615516345681223344556899912344566791244457889912234456675566778990002344446991357882770245836790113723466789234613466667800013566780022255556667899015023347825678134566771134489817889990123477891466725667781235669903122788124801234790224903367901223556666925568800224566678895556671678990011223568990025667888999012334677700125045669925567700125668367084568012455708014455777780012344568060157934471348992334789493678124835677467902379901279480234578889581491268926628223460234456802557800224900224578111358147814801450034778936781339135015581122590357834900104567135779915799261345793467247922345670011290244556693556802345566780245570012345679156843436711347813677159334501367819579569123344561112344455566779113344578992344556892344556679012344666780247779 
                                                                                                                                739050270506147134563609478158299440104492531900254393434816897995707675760324358237395579439229725954956690396700692572840924362303642813014309701561864328129258893752326647813681787048680778359014916284338081081102485139501240295856746148103938749657202434253318513260679806719192820280191055727232637845923023207512833582451456760264538188010476047091178112343060787128741094423267810905233123791223571259972446726891565516128592367038998505139581524868881580372907034718348495293628982246959204658297743249670774604695664076061456525894949076834536862596842347562905272862680668188079237998192914548252024365706981714065246451615191806427298200729068965890713897129545921717468142035247484416555727524643461053967045386408420173303315197632852246265912967753384014810358061670069452528234143953962254301860140894620936929815294943436227323302061687839056106376866641223798272302665028466796181034334767157306942768795437893144483228314647709810257746519226672547541907040781002612707172455979401588647045188448271654658606369233541357

JJackson · Sep 24, 2014

Re: West Africa: Ebola Outbreak Strains Sequenced

Re: West Africa: Ebola Outbreak Strains Sequenced

gsgs said:
twice as much -if correct- would be a surprisingly big increase, as compared with flu, where I get a ~30% increase and in HA only in the years after the 1968 pandemic.

30% compared to what?
1968 was a reassortment event rather than a zoonotic emergence so there is no non human reservoir in which it is endemic for comparison purposes.

One other point to consider, in some of the wilder genetic mutation scenarios, is flu has a segmented genome where as EBOV is single stranded. Both are -ssRNA viruses so need to supply their own RNP. In flu this accounts for about half the coding region and I assume the same would apply for EBOV which (I think) has a slightly larger exon. The big difference is reassortment which allows flu to make instant massive changes - this is not an option for single stranded Ebola.

gsgs · Sep 24, 2014

Re: Science: Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

30% as compared to later years

it was a new host, HA was a bit "nervous" to adapt ?!?

what you mean with "half the coding region " ?

in flu almost everything codes (>90%) and some regions even twice
with different reading frames

ps. I'm updating the list and graph above now with partial sequences included,
wait until after lunch
------------edit-------------
well, only 6 partials, so I skipped that
so, I have 148 ebola-zaire sequences, file ebozai6

--------edit---------glycoprotein amino-acids mutation-picture added

Science: Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

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