tetano
Editor, Senior Moderator
Sci Total Environ
. 2024 Apr 11:172299.
doi: 10.1016/j.scitotenv.2024.172299. Online ahead of print. Differentiated impacts of short-term exposure to fine particulate constituents on infectious diseases in 507 cities of Chinese children and adolescents: A nationwide time-stratified case-crossover study from 2008 to 2021
Li Chen[SUP] 1 [/SUP], Wen Yuan[SUP] 2 [/SUP], Mengjie Geng[SUP] 3 [/SUP], Rongbin Xu[SUP] 4 [/SUP], Yi Xing[SUP] 2 [/SUP], Bo Wen[SUP] 4 [/SUP], Yao Wu[SUP] 4 [/SUP], Xiang Ren[SUP] 3 [/SUP], Yue Shi[SUP] 3 [/SUP], Yi Zhang[SUP] 2 [/SUP], Xinli Song[SUP] 2 [/SUP], Yang Qin[SUP] 2 [/SUP], RuoLin Wang[SUP] 2 [/SUP], Jianuo Jiang[SUP] 2 [/SUP], Ziqi Dong[SUP] 2 [/SUP], Jieyu Liu[SUP] 2 [/SUP], Tongjun Guo[SUP] 2 [/SUP], Zhiying Song[SUP] 2 [/SUP], Liping Wang[SUP] 3 [/SUP], Yinghua Ma[SUP] 1 [/SUP], Yanhui Dong[SUP] 5 [/SUP], Yi Song[SUP] 6 [/SUP], Jun Ma[SUP] 1 [/SUP]
Affiliations
This study assesses the association of short-term exposure to PM[SUB]2.5[/SUB] (particles ≤2.5 μm) on infectious diseases among Chinese children and adolescents. Analyzing data from 507 cities (2008-2021) on 42 diseases, it focuses on PM[SUB]2.5[/SUB] components (black carbon (BC), ammonium (NH[SUB]4[/SUB][SUP]+[/SUP]), inorganic nitrate (NO[SUB]3[/SUB][SUP]-[/SUP]), organic matter (OM), and sulfate (SO[SUB]4[/SUB][SUP]2-[/SUP])). PM[SUB]2.5[/SUB] constituents significantly associated with incidence. Sulfate showed the most substantial effect, increasing all-cause infectious disease risk by 2.72 % per interquartile range (IQR) increase. It was followed by BC (2.04 % increase), OM (1.70 %), NO[SUB]3[/SUB][SUP]-[/SUP] (1.67 %), and NH[SUB]4[/SUB][SUP]+[/SUP] (0.79 %). Specifically, sulfate and BC had pronounced impacts on respiratory diseases, with sulfate linked to a 10.73 % increase in seasonal influenza risk and NO[SUB]3[/SUB][SUP]-[/SUP] to a 16.39 % rise in tuberculosis. Exposure to PM[SUB]2.5[/SUB] also marginally increased risks for gastrointestinal, enterovirus, and vectorborne diseases like dengue (7.46 % increase with SO[SUB]4[/SUB][SUP]2-[/SUP]). Sexually transmitted and bloodborne diseases saw an approximate 6.26 % increase in incidence, with specific constituents linked to diseases like hepatitis C and syphilis. The study concludes that managing PM[SUB]2.5[/SUB] levels could substantially reduce infectious disease incidence, particularly in China's middle-northern regions. It highlights the necessity of stringent air quality standards and targeted disease prevention, aligning PM[SUB]2.5[/SUB] management with international guidelines for public health protection.
Keywords: Child; Infectious diseases; PM(2.5); PM(2.5) constituents; Time series.
. 2024 Apr 11:172299.
doi: 10.1016/j.scitotenv.2024.172299. Online ahead of print. Differentiated impacts of short-term exposure to fine particulate constituents on infectious diseases in 507 cities of Chinese children and adolescents: A nationwide time-stratified case-crossover study from 2008 to 2021
Li Chen[SUP] 1 [/SUP], Wen Yuan[SUP] 2 [/SUP], Mengjie Geng[SUP] 3 [/SUP], Rongbin Xu[SUP] 4 [/SUP], Yi Xing[SUP] 2 [/SUP], Bo Wen[SUP] 4 [/SUP], Yao Wu[SUP] 4 [/SUP], Xiang Ren[SUP] 3 [/SUP], Yue Shi[SUP] 3 [/SUP], Yi Zhang[SUP] 2 [/SUP], Xinli Song[SUP] 2 [/SUP], Yang Qin[SUP] 2 [/SUP], RuoLin Wang[SUP] 2 [/SUP], Jianuo Jiang[SUP] 2 [/SUP], Ziqi Dong[SUP] 2 [/SUP], Jieyu Liu[SUP] 2 [/SUP], Tongjun Guo[SUP] 2 [/SUP], Zhiying Song[SUP] 2 [/SUP], Liping Wang[SUP] 3 [/SUP], Yinghua Ma[SUP] 1 [/SUP], Yanhui Dong[SUP] 5 [/SUP], Yi Song[SUP] 6 [/SUP], Jun Ma[SUP] 1 [/SUP]
Affiliations
- PMID: 38614340
- DOI: 10.1016/j.scitotenv.2024.172299
This study assesses the association of short-term exposure to PM[SUB]2.5[/SUB] (particles ≤2.5 μm) on infectious diseases among Chinese children and adolescents. Analyzing data from 507 cities (2008-2021) on 42 diseases, it focuses on PM[SUB]2.5[/SUB] components (black carbon (BC), ammonium (NH[SUB]4[/SUB][SUP]+[/SUP]), inorganic nitrate (NO[SUB]3[/SUB][SUP]-[/SUP]), organic matter (OM), and sulfate (SO[SUB]4[/SUB][SUP]2-[/SUP])). PM[SUB]2.5[/SUB] constituents significantly associated with incidence. Sulfate showed the most substantial effect, increasing all-cause infectious disease risk by 2.72 % per interquartile range (IQR) increase. It was followed by BC (2.04 % increase), OM (1.70 %), NO[SUB]3[/SUB][SUP]-[/SUP] (1.67 %), and NH[SUB]4[/SUB][SUP]+[/SUP] (0.79 %). Specifically, sulfate and BC had pronounced impacts on respiratory diseases, with sulfate linked to a 10.73 % increase in seasonal influenza risk and NO[SUB]3[/SUB][SUP]-[/SUP] to a 16.39 % rise in tuberculosis. Exposure to PM[SUB]2.5[/SUB] also marginally increased risks for gastrointestinal, enterovirus, and vectorborne diseases like dengue (7.46 % increase with SO[SUB]4[/SUB][SUP]2-[/SUP]). Sexually transmitted and bloodborne diseases saw an approximate 6.26 % increase in incidence, with specific constituents linked to diseases like hepatitis C and syphilis. The study concludes that managing PM[SUB]2.5[/SUB] levels could substantially reduce infectious disease incidence, particularly in China's middle-northern regions. It highlights the necessity of stringent air quality standards and targeted disease prevention, aligning PM[SUB]2.5[/SUB] management with international guidelines for public health protection.
Keywords: Child; Infectious diseases; PM(2.5); PM(2.5) constituents; Time series.