tetano
Editor, Senior Moderator
Sci Total Environ. 2020 Apr 4;725:138277. doi: 10.1016/j.scitotenv.2020.138277. [Epub ahead of print]
COVID-19: A promising cure for the global panic.
Vellingiri B[SUP]1[/SUP], Jayaramayya K[SUP]2[/SUP], Iyer M[SUP]2[/SUP], Narayanasamy A[SUP]3[/SUP], Govindasamy V[SUP]4[/SUP], Giridharan B[SUP]5[/SUP], Ganesan S[SUP]6[/SUP], Venugopal A[SUP]7[/SUP], Venkatesan D[SUP]7[/SUP], Ganesan H[SUP]7[/SUP], Rajagopalan K[SUP]7[/SUP], Rahman PKSM[SUP]8[/SUP], Cho SG[SUP]9[/SUP], Kumar NS[SUP]10[/SUP], Subramaniam MD[SUP]11[/SUP].
Author information
Abstract
The novel Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, which is the causative agent of a potentially fatal disease that is of great global public health concern. The outbreak of COVID-19 is wreaking havoc worldwide due to inadequate risk assessment regarding the urgency of the situation. The COVID-19 pandemic has entered a dangerous new phase. When compared with SARS and MERS, COVID-19 has spread more rapidly, due to increased globalization and adaptation of the virus in every environment. Slowing the spread of the COVID-19 cases will significantly reduce the strain on the healthcare system of the country by limiting the number of people who are severely sick by COVID-19 and need hospital care. Hence, the recent outburst of COVID-19 highlights an urgent need for therapeutics targeting SARS-CoV-2. Here, we have discussed the structure of virus; varying symptoms among COVID-19, SARS, MERS and common flu; the probable mechanism behind the infection and its immune response. Further, the current treatment options, drugs available, ongoing trials and recent diagnostics for COVID-19 have been discussed. We suggest traditional Indian medicinal plants as possible novel therapeutic approaches, exclusively targeting SARS-CoV-2 and its pathways.
Copyright ? 2020 Elsevier B.V. All rights reserved.
KEYWORDS:
Coronavirus disease 2019 (COVID-19); Indian traditional medicine; Mechanism of action; SARS-CoV-2; Therapeutic approach
PMID:32278175DOI:10.1016/j.scitotenv.2020.138277
COVID-19: A promising cure for the global panic.
Vellingiri B[SUP]1[/SUP], Jayaramayya K[SUP]2[/SUP], Iyer M[SUP]2[/SUP], Narayanasamy A[SUP]3[/SUP], Govindasamy V[SUP]4[/SUP], Giridharan B[SUP]5[/SUP], Ganesan S[SUP]6[/SUP], Venugopal A[SUP]7[/SUP], Venkatesan D[SUP]7[/SUP], Ganesan H[SUP]7[/SUP], Rajagopalan K[SUP]7[/SUP], Rahman PKSM[SUP]8[/SUP], Cho SG[SUP]9[/SUP], Kumar NS[SUP]10[/SUP], Subramaniam MD[SUP]11[/SUP].
Author information
Abstract
The novel Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, which is the causative agent of a potentially fatal disease that is of great global public health concern. The outbreak of COVID-19 is wreaking havoc worldwide due to inadequate risk assessment regarding the urgency of the situation. The COVID-19 pandemic has entered a dangerous new phase. When compared with SARS and MERS, COVID-19 has spread more rapidly, due to increased globalization and adaptation of the virus in every environment. Slowing the spread of the COVID-19 cases will significantly reduce the strain on the healthcare system of the country by limiting the number of people who are severely sick by COVID-19 and need hospital care. Hence, the recent outburst of COVID-19 highlights an urgent need for therapeutics targeting SARS-CoV-2. Here, we have discussed the structure of virus; varying symptoms among COVID-19, SARS, MERS and common flu; the probable mechanism behind the infection and its immune response. Further, the current treatment options, drugs available, ongoing trials and recent diagnostics for COVID-19 have been discussed. We suggest traditional Indian medicinal plants as possible novel therapeutic approaches, exclusively targeting SARS-CoV-2 and its pathways.
Copyright ? 2020 Elsevier B.V. All rights reserved.
KEYWORDS:
Coronavirus disease 2019 (COVID-19); Indian traditional medicine; Mechanism of action; SARS-CoV-2; Therapeutic approach
PMID:32278175DOI:10.1016/j.scitotenv.2020.138277