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Sci Total Environ . Coronavirus-mimicking nanoparticles (CorNPs) in artificial saliva droplets and nanoaerosols: Influence of shape and environment

tetano

Editor, Senior Moderator
Sci Total Environ


. 2022 Nov 25;160503.
doi: 10.1016/j.scitotenv.2022.160503. Online ahead of print.
Coronavirus-mimicking nanoparticles (CorNPs) in artificial saliva droplets and nanoaerosols: Influence of shape and environmental factors on particokinetics/particle aerodynamics


Ajay Vikram Singh[SUP] 1 [/SUP], Aaron Katz[SUP] 2 [/SUP], Romi Singh Maharajan[SUP] 2 [/SUP], Ashish K Gadicherla[SUP] 3 [/SUP], Martin Richter[SUP] 3 [/SUP], Jan Heyda[SUP] 4 [/SUP], Pablo Del Pino[SUP] 5 [/SUP], Peter Laux[SUP] 2 [/SUP], Andreas Luch[SUP] 2 [/SUP]



Affiliations

Abstract

Severe acute respiratory syndrome coronavirus 2, abbreviated as SARS-CoV-2, has been associated with the transmission of infectious COVID-19 disease through breathing and speech droplets emitted by infected carriers including asymptomatic cases. As part of SARS-CoV-2 global pandemic preparedness, we studied the transmission of aerosolized air mimicking the infected person releasing speech aerosol with droplets containing CorNPs using a vibrating mesh nebulizer as human patient simulator. Generally speech produces nanoaerosols with droplets of <5 μm in diameter that can travel distances longer than 1 m after release. It is assumed that speech aerosol droplets are a main element of the current Corona virus pandemic, unlike droplets larger than 5 m, which settle down within a 1 m radius. There are no systemic studies, which take into account speech-generated aerosol/droplet experimental validation and their aerodynamics/particle kinetics analysis. In this study, we cover these topics and explore role of residual water in aerosol droplet stability by exploring drying dynamics. Furthermore, a candle experiment was designed to determine whether air pollution might influence respiratory virus like nanoparticle transmission and air stability.

Keywords: Aerodynamics; Gold nanourchins; Nebulization; Particokinetics; SARS-CoV-2.
 
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