tetano
Editor, Senior Moderator
Sci Rep
. 2021 Apr 16;11(1):8380.
doi: 10.1038/s41598-021-87688-9.
SARS-CoV-2 seroprevalence in healthcare workers at a frontline hospital in Tokyo
Hiroshi Fukuda[SUP] 1 2 3 [/SUP], Kuniaki Seyama[SUP] 4 2 3 [/SUP], Kanami Ito[SUP] 2 3 [/SUP], Tomohiko Ai[SUP] 5 3 [/SUP], Shuko Nojiri[SUP] 6 3 [/SUP], Satoshi Hori[SUP] 4 2 7 8 3 [/SUP], Mitsuru Wakita[SUP] 9 3 [/SUP], Kaori Saito[SUP] 5 3 [/SUP], Yuka Shida[SUP] 2 3 [/SUP], Rie Nagura[SUP] 2 3 [/SUP], Mayu Hasegawa[SUP] 2 3 [/SUP], Chiaki Kanemoto[SUP] 2 3 [/SUP], Mayumi Tokuhara[SUP] 2 3 [/SUP], Katsunobu Okajima[SUP] 2 3 [/SUP], Yukio Yoshikawa[SUP] 2 3 [/SUP], Narimasa Katsuta[SUP] 2 9 3 [/SUP], Takamasa Yamamoto[SUP] 9 3 [/SUP], Mayumi Idei[SUP] 5 6 3 [/SUP], Yuki Horiuchi[SUP] 5 3 [/SUP], Kotoko Yamatani[SUP] 5 3 [/SUP], Shigeki Misawa[SUP] 9 3 [/SUP], Toshio Naito[SUP] 1 3 [/SUP], Takashi Miida[SUP] 5 3 [/SUP], Hiroyuki Sato[SUP] 2 3 [/SUP], Nobutaka Hattori[SUP] 2 3 10 [/SUP], Yoko Tabe[SUP] 11 12 13 [/SUP], Kazuhisa Takahashi[SUP] 4 3 [/SUP]
Affiliations
Abstract
Healthcare workers (HCWs) are highly exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The actual coronavirus disease (COVID-19) situation, especially in regions that are less affected, has not yet been determined. This study aimed to assess the seroprevalence of SARS-CoV-2 in HCWs working in a frontline hospital in Tokyo, Japan. In this cross-sectional observational study, screening was performed on consented HCWs, including medical, nursing, and other workers, as part of a mandatory health checkup. The screening test results and clinical characteristics of the participants were recorded. The antibody seroprevalence rate among the 4147 participants screened between July 6 and August 21, 2020, was 0.34% (14/4147). There was no significant difference in the seroprevalence rate between frontline HCWs with a high exposure risk and HCWs working in other settings with a low exposure risk. Of those seropositive for SARS-CoV-2, 64% (9/14) were not aware of any symptoms and had not previously been diagnosed with COVID-19. In conclusion, this study provides insights into the extent of infection and immune status in HCWs in Japan, which has a relatively low prevalence of COVID-19. Our findings aid in formulating public health policies to control virus spread in regions with low-intensity COVID-19.
. 2021 Apr 16;11(1):8380.
doi: 10.1038/s41598-021-87688-9.
SARS-CoV-2 seroprevalence in healthcare workers at a frontline hospital in Tokyo
Hiroshi Fukuda[SUP] 1 2 3 [/SUP], Kuniaki Seyama[SUP] 4 2 3 [/SUP], Kanami Ito[SUP] 2 3 [/SUP], Tomohiko Ai[SUP] 5 3 [/SUP], Shuko Nojiri[SUP] 6 3 [/SUP], Satoshi Hori[SUP] 4 2 7 8 3 [/SUP], Mitsuru Wakita[SUP] 9 3 [/SUP], Kaori Saito[SUP] 5 3 [/SUP], Yuka Shida[SUP] 2 3 [/SUP], Rie Nagura[SUP] 2 3 [/SUP], Mayu Hasegawa[SUP] 2 3 [/SUP], Chiaki Kanemoto[SUP] 2 3 [/SUP], Mayumi Tokuhara[SUP] 2 3 [/SUP], Katsunobu Okajima[SUP] 2 3 [/SUP], Yukio Yoshikawa[SUP] 2 3 [/SUP], Narimasa Katsuta[SUP] 2 9 3 [/SUP], Takamasa Yamamoto[SUP] 9 3 [/SUP], Mayumi Idei[SUP] 5 6 3 [/SUP], Yuki Horiuchi[SUP] 5 3 [/SUP], Kotoko Yamatani[SUP] 5 3 [/SUP], Shigeki Misawa[SUP] 9 3 [/SUP], Toshio Naito[SUP] 1 3 [/SUP], Takashi Miida[SUP] 5 3 [/SUP], Hiroyuki Sato[SUP] 2 3 [/SUP], Nobutaka Hattori[SUP] 2 3 10 [/SUP], Yoko Tabe[SUP] 11 12 13 [/SUP], Kazuhisa Takahashi[SUP] 4 3 [/SUP]
Affiliations
- PMID: 33863960
- DOI: 10.1038/s41598-021-87688-9
Abstract
Healthcare workers (HCWs) are highly exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The actual coronavirus disease (COVID-19) situation, especially in regions that are less affected, has not yet been determined. This study aimed to assess the seroprevalence of SARS-CoV-2 in HCWs working in a frontline hospital in Tokyo, Japan. In this cross-sectional observational study, screening was performed on consented HCWs, including medical, nursing, and other workers, as part of a mandatory health checkup. The screening test results and clinical characteristics of the participants were recorded. The antibody seroprevalence rate among the 4147 participants screened between July 6 and August 21, 2020, was 0.34% (14/4147). There was no significant difference in the seroprevalence rate between frontline HCWs with a high exposure risk and HCWs working in other settings with a low exposure risk. Of those seropositive for SARS-CoV-2, 64% (9/14) were not aware of any symptoms and had not previously been diagnosed with COVID-19. In conclusion, this study provides insights into the extent of infection and immune status in HCWs in Japan, which has a relatively low prevalence of COVID-19. Our findings aid in formulating public health policies to control virus spread in regions with low-intensity COVID-19.