tetano
Editor, Senior Moderator
Sci Rep
. 2022 May 5;12(1):7395.
doi: 10.1038/s41598-022-11303-8.
Longitudinal analysis of built environment and aerosol contamination associated with isolated COVID-19 positive individuals
Patrick F Horve[SUP] 1 2 [/SUP], Leslie G Dietz[SUP] 2 [/SUP], Garis Bowles[SUP] 2 [/SUP], Georgia MacCrone[SUP] 2 [/SUP], Andreas Olsen-Martinez[SUP] 2 [/SUP], Dale Northcutt[SUP] 2 3 [/SUP], Vincent Moore[SUP] 2 [/SUP], Liliana Barnatan[SUP] 2 [/SUP], Hooman Parhizkar[SUP] 3 4 [/SUP], Kevin G Van Den Wymelenberg[SUP] 5 6 7 [/SUP]
Affiliations
Abstract
The indoor environment is the primary location for the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), largely driven by respiratory particle accumulation in the air and increased connectivity between the individuals occupying indoor spaces. In this study, we aimed to track a cohort of subjects as they occupied a COVID-19 isolation dormitory to better understand the impact of subject and environmental viral load over time, symptoms, and room ventilation on the detectable viral load within a single room. We find that subject samples demonstrate a decrease in overall viral load over time, symptoms significantly impact environmental viral load, and we provide the first real-world evidence for decreased aerosol SARS-CoV-2 load with increasing ventilation, both from mechanical and window sources. These results may guide environmental viral surveillance strategies and be used to better control the spread of SARS-CoV-2 within built environments and better protect those caring for individuals with COVID-19.
. 2022 May 5;12(1):7395.
doi: 10.1038/s41598-022-11303-8.
Longitudinal analysis of built environment and aerosol contamination associated with isolated COVID-19 positive individuals
Patrick F Horve[SUP] 1 2 [/SUP], Leslie G Dietz[SUP] 2 [/SUP], Garis Bowles[SUP] 2 [/SUP], Georgia MacCrone[SUP] 2 [/SUP], Andreas Olsen-Martinez[SUP] 2 [/SUP], Dale Northcutt[SUP] 2 3 [/SUP], Vincent Moore[SUP] 2 [/SUP], Liliana Barnatan[SUP] 2 [/SUP], Hooman Parhizkar[SUP] 3 4 [/SUP], Kevin G Van Den Wymelenberg[SUP] 5 6 7 [/SUP]
Affiliations
- PMID: 35513399
- DOI: 10.1038/s41598-022-11303-8
Abstract
The indoor environment is the primary location for the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), largely driven by respiratory particle accumulation in the air and increased connectivity between the individuals occupying indoor spaces. In this study, we aimed to track a cohort of subjects as they occupied a COVID-19 isolation dormitory to better understand the impact of subject and environmental viral load over time, symptoms, and room ventilation on the detectable viral load within a single room. We find that subject samples demonstrate a decrease in overall viral load over time, symptoms significantly impact environmental viral load, and we provide the first real-world evidence for decreased aerosol SARS-CoV-2 load with increasing ventilation, both from mechanical and window sources. These results may guide environmental viral surveillance strategies and be used to better control the spread of SARS-CoV-2 within built environments and better protect those caring for individuals with COVID-19.
