tetano
Editor, Senior Moderator
Sci Rep
. 2024 Mar 13;14(1):6072.
doi: 10.1038/s41598-024-56462-y. Factors associated with the SARS-CoV-2 immunoglobulin-G titer levels in convalescent whole-blood donors: a Chinese cross-sectional study
Donglin Tan[SUP] #[/SUP][SUP] 1 [/SUP], Xinman Du[SUP] #[/SUP][SUP] 2 [/SUP], Jingyun Tang[SUP] 2 [/SUP], Humin Liu[SUP] 3 [/SUP], Meng Li[SUP] 2 [/SUP], Jianxun Kang[SUP] 2 [/SUP], Xiaochun Li[SUP] 1 [/SUP], Ying Li[SUP] 3 [/SUP], Yue Luo[SUP] 2 [/SUP], Qing Wang[SUP] 4 [/SUP], Xiaobo Gu[SUP] 4 [/SUP], Zonghan Zhao[SUP] 4 [/SUP], Xuemei Fu[SUP] #[/SUP][SUP] 5 [/SUP], Xue Chen[SUP] #[/SUP][SUP] 6 [/SUP]
Affiliations
Blood transfusions from convalescent Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infected patients could be used to treat patients with severe infections or immunocompromised patients. However, it is necessary to select the optimal donors to maximize the utilization of resources. In this study, we investigated the associations among body mass index (BMI), tobacco smoking, exercise frequency and duration, and alcohol consumption with the SARS-CoV-2 immunoglobulin-G (IgG) antibody titer levels with in the Chinese convalescent blood donor population. Here we show that BMI, smoking habits, and exercise frequency appear to be predictive factors for IgG levels in convalescent male blood donors. However, these variables were not observed as predictive of IgG levels in female convalescent blood donors. The findings could be used to optimize the screening for potential blood donors to treat immunocompromised or severely ill COVID-19 patients.
. 2024 Mar 13;14(1):6072.
doi: 10.1038/s41598-024-56462-y. Factors associated with the SARS-CoV-2 immunoglobulin-G titer levels in convalescent whole-blood donors: a Chinese cross-sectional study
Donglin Tan[SUP] #[/SUP][SUP] 1 [/SUP], Xinman Du[SUP] #[/SUP][SUP] 2 [/SUP], Jingyun Tang[SUP] 2 [/SUP], Humin Liu[SUP] 3 [/SUP], Meng Li[SUP] 2 [/SUP], Jianxun Kang[SUP] 2 [/SUP], Xiaochun Li[SUP] 1 [/SUP], Ying Li[SUP] 3 [/SUP], Yue Luo[SUP] 2 [/SUP], Qing Wang[SUP] 4 [/SUP], Xiaobo Gu[SUP] 4 [/SUP], Zonghan Zhao[SUP] 4 [/SUP], Xuemei Fu[SUP] #[/SUP][SUP] 5 [/SUP], Xue Chen[SUP] #[/SUP][SUP] 6 [/SUP]
Affiliations
- PMID: 38480826
- DOI: 10.1038/s41598-024-56462-y
Blood transfusions from convalescent Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infected patients could be used to treat patients with severe infections or immunocompromised patients. However, it is necessary to select the optimal donors to maximize the utilization of resources. In this study, we investigated the associations among body mass index (BMI), tobacco smoking, exercise frequency and duration, and alcohol consumption with the SARS-CoV-2 immunoglobulin-G (IgG) antibody titer levels with in the Chinese convalescent blood donor population. Here we show that BMI, smoking habits, and exercise frequency appear to be predictive factors for IgG levels in convalescent male blood donors. However, these variables were not observed as predictive of IgG levels in female convalescent blood donors. The findings could be used to optimize the screening for potential blood donors to treat immunocompromised or severely ill COVID-19 patients.