tetano
Editor, Senior Moderator
Sci Rep
. 2021 Feb 22;11(1):4304.
doi: 10.1038/s41598-021-83654-7.
Correlation between early features and prognosis of symptomatic COVID-19 discharged patients in Hunan, China
Yeyu Cai[SUP] #[/SUP][SUP] 1 [/SUP], Jiayi Liu[SUP] #[/SUP][SUP] 1 [/SUP], Haitao Yang[SUP] 1 [/SUP], Taili Chen[SUP] 2 [/SUP], Qizhi Yu[SUP] 3 [/SUP], Juan Chen[SUP] 4 [/SUP], Deng Huang[SUP] 5 [/SUP], Zhu Chen[SUP] 1 [/SUP], Quan-Liang Shang[SUP] 1 [/SUP], Cong Ma[SUP] 1 [/SUP], Xiangyu Chen[SUP] 6 [/SUP], Enhua Xiao[SUP] 7 8 [/SUP]
Affiliations
Abstract
To determine the correlation between the clinical, laboratory, and radiological findings and the hospitalization days in Coronavirus Infectious Disease-19 (COVID-19) discharged patients. We retrospectively identified 172 discharged patients with COVID-19 pneumonia from January 10, 2020, to February 28, 2020, in Hunan province. The patients were categorized into group 1 (≤ 19 days) and group 2 (> 19 days) based on the time from symptom onset to discharge. Cough during admission occurred more commonly in group 2 (68.4%) than in group 1 (53.1%, p = 0.042). White blood cell (p = 0.045), neutrophil counts (p = 0.023), Alanine aminotransferase (p = 0.029), Aspartate aminotransferase (p = 0.027) and Lactate dehydrogenase (p = 0.021) that were above normal were more common in group 2. Patients with single lesions were observed more in group 1(17.7%, p = 0.018) and multiple lesions observed more in group 2(86.8%, p = 0.012). The number of lobes involved (p = 0.008) in the CT score (p = 0.001) for each patient was all differences between the two groups with a statistically significant difference. Mixed ground-glass opacity (GGO) and consolidation appearances were observed in most patients. GGO components > consolidation appearance was more common in group 1 (25.0%) than in group 2 (8.0%) with a significant difference (0.015), GGO < consolidation was more common in group 2(71.1%, p = 0.012). From the logistic regression analysis, the CT score (OR, 1.223; 95% CI, 1.004 to 1.491, p = 0.046) and the appearance of GGO > consolidation (OR, 0.150; 95% CI, 0.034 to 0.660, p = 0.012) were independently associated with the hospitalization days. Thus, special attention should be paid to the role of radiological features in monitoring the disease prognosis.
. 2021 Feb 22;11(1):4304.
doi: 10.1038/s41598-021-83654-7.
Correlation between early features and prognosis of symptomatic COVID-19 discharged patients in Hunan, China
Yeyu Cai[SUP] #[/SUP][SUP] 1 [/SUP], Jiayi Liu[SUP] #[/SUP][SUP] 1 [/SUP], Haitao Yang[SUP] 1 [/SUP], Taili Chen[SUP] 2 [/SUP], Qizhi Yu[SUP] 3 [/SUP], Juan Chen[SUP] 4 [/SUP], Deng Huang[SUP] 5 [/SUP], Zhu Chen[SUP] 1 [/SUP], Quan-Liang Shang[SUP] 1 [/SUP], Cong Ma[SUP] 1 [/SUP], Xiangyu Chen[SUP] 6 [/SUP], Enhua Xiao[SUP] 7 8 [/SUP]
Affiliations
- PMID: 33619362
- DOI: 10.1038/s41598-021-83654-7
Abstract
To determine the correlation between the clinical, laboratory, and radiological findings and the hospitalization days in Coronavirus Infectious Disease-19 (COVID-19) discharged patients. We retrospectively identified 172 discharged patients with COVID-19 pneumonia from January 10, 2020, to February 28, 2020, in Hunan province. The patients were categorized into group 1 (≤ 19 days) and group 2 (> 19 days) based on the time from symptom onset to discharge. Cough during admission occurred more commonly in group 2 (68.4%) than in group 1 (53.1%, p = 0.042). White blood cell (p = 0.045), neutrophil counts (p = 0.023), Alanine aminotransferase (p = 0.029), Aspartate aminotransferase (p = 0.027) and Lactate dehydrogenase (p = 0.021) that were above normal were more common in group 2. Patients with single lesions were observed more in group 1(17.7%, p = 0.018) and multiple lesions observed more in group 2(86.8%, p = 0.012). The number of lobes involved (p = 0.008) in the CT score (p = 0.001) for each patient was all differences between the two groups with a statistically significant difference. Mixed ground-glass opacity (GGO) and consolidation appearances were observed in most patients. GGO components > consolidation appearance was more common in group 1 (25.0%) than in group 2 (8.0%) with a significant difference (0.015), GGO < consolidation was more common in group 2(71.1%, p = 0.012). From the logistic regression analysis, the CT score (OR, 1.223; 95% CI, 1.004 to 1.491, p = 0.046) and the appearance of GGO > consolidation (OR, 0.150; 95% CI, 0.034 to 0.660, p = 0.012) were independently associated with the hospitalization days. Thus, special attention should be paid to the role of radiological features in monitoring the disease prognosis.