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Sci Rep . Coronavirus disease-related in-hospital mortality: a cohort study in a private healthcare network in Brazil

tetano

Editor, Senior Moderator
Sci Rep


. 2022 Apr 16;12(1):6371.
doi: 10.1038/s41598-022-10343-4.
Coronavirus disease-related in-hospital mortality: a cohort study in a private healthcare network in Brazil


Helidea de Oliveira Lima[SUP] 1 [/SUP], Leopoldo Muniz da Silva[SUP] 2 [/SUP], Arthur de Campos Vieira Abib[SUP] 2 [/SUP], Leandro Reis Tavares[SUP] 1 [/SUP], Daniel Wagner de Castro Lima Santos[SUP] 3 [/SUP], Ana Claudia Lopes Fernandes de Araújo[SUP] 1 [/SUP], Laise Pereira Moreira[SUP] 1 [/SUP], Saullo Queiroz Silveira[SUP] 2 [/SUP], Vanessa de Melo Silva Torres[SUP] 1 [/SUP], Deborah Simões[SUP] 1 [/SUP], Ramiro Arellano[SUP] 4 [/SUP], Anthony M-H Ho[SUP] 4 [/SUP], Glenio B Mizubuti[SUP] 5 [/SUP]



Affiliations

Abstract

COVID-19-related in-hospital mortality has been reported at 30.7-47.3% in Brazil, however studies assessing exclusively private hospitals are lacking. This is important because of significant differences existing between the Brazilian private and public healthcare systems. We aimed to determine the COVID-19-related in-hospital mortality and associated risk factors in a Brazilian private network from March/2020 to March/2021. Data were extracted from institutional database and analyzed using Cox regression model. Length of hospitalization and death-related factors were modeled based on available independent variables. In total, 38,937 COVID-19 patients were hospitalized of whom 3058 (7.8%) died. Admission to the intensive care unit occurred in 62.5% of cases, and 11.5% and 3.8% required mechanical ventilation (MV) and renal replacement therapy (RRT), respectively. In the adjusted model, age ≥ 61 years-old, comorbidities, and the need for MV and/or RRT were significantly associated with increased mortality (p < 0.05). Obesity and hypertension were associated with the need for MV and RRT (p < 0.05).
 
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