tetano
Editor, Senior Moderator
Scand J Immunol
. 2024 Feb;99(2):e13345.
doi: 10.1111/sji.13345. Epub 2023 Dec 6. To be remembered: B cell memory response against SARS-CoV-2 and its variants in vaccinated and unvaccinated individuals
Nafees Ahmed[SUP] 1 [/SUP], Atharv Athavale[SUP] 1 [/SUP], Ankita H Tripathi[SUP] 2 [/SUP], Adarsh Subramaniam[SUP] 1 [/SUP], Santosh K Upadhyay[SUP] 2 [/SUP], Anil Kumar Pandey[SUP] 3 [/SUP], Ramesh Chandra Rai[SUP] 1 [/SUP], Amit Awasthi[SUP] 1 [/SUP]
Affiliations
COVID-19 disease has plagued the world economy and affected the overall well-being and life of most of the people. Natural infection as well as vaccination leads to the development of an immune response against the pathogen. This involves the production of antibodies, which can neutralize the virus during future challenges. In addition, the development of cellular immune memory with memory B and T cells provides long-lasting protection. The longevity of the immune response has been a subject of intensive research in this field. The extent of immunity conferred by different forms of vaccination or natural infections remained debatable for long. Hence, understanding the effectiveness of these responses among different groups of people can assist government organizations in making informed policy decisions. In this article, based on the publicly available data, we have reviewed the memory response generated by some of the vaccines against SARS-CoV-2 and its variants, particularly B cell memory in different groups of individuals.
Keywords: SARS‐CoV‐2; hybrid immunity; immune response; memory B cell; vaccine.
. 2024 Feb;99(2):e13345.
doi: 10.1111/sji.13345. Epub 2023 Dec 6. To be remembered: B cell memory response against SARS-CoV-2 and its variants in vaccinated and unvaccinated individuals
Nafees Ahmed[SUP] 1 [/SUP], Atharv Athavale[SUP] 1 [/SUP], Ankita H Tripathi[SUP] 2 [/SUP], Adarsh Subramaniam[SUP] 1 [/SUP], Santosh K Upadhyay[SUP] 2 [/SUP], Anil Kumar Pandey[SUP] 3 [/SUP], Ramesh Chandra Rai[SUP] 1 [/SUP], Amit Awasthi[SUP] 1 [/SUP]
Affiliations
- PMID: 38441373
- DOI: 10.1111/sji.13345
COVID-19 disease has plagued the world economy and affected the overall well-being and life of most of the people. Natural infection as well as vaccination leads to the development of an immune response against the pathogen. This involves the production of antibodies, which can neutralize the virus during future challenges. In addition, the development of cellular immune memory with memory B and T cells provides long-lasting protection. The longevity of the immune response has been a subject of intensive research in this field. The extent of immunity conferred by different forms of vaccination or natural infections remained debatable for long. Hence, understanding the effectiveness of these responses among different groups of people can assist government organizations in making informed policy decisions. In this article, based on the publicly available data, we have reviewed the memory response generated by some of the vaccines against SARS-CoV-2 and its variants, particularly B cell memory in different groups of individuals.
Keywords: SARS‐CoV‐2; hybrid immunity; immune response; memory B cell; vaccine.