tetano
Editor, Senior Moderator
Saudi Med J
. 2020 Nov;41(11):1204-1210.
doi: 10.15537/smj.2020.11.25466.
Acute cardiac injury is associated with adverse outcomes, including mortality in COVID-19 patients. A single-center experience
Kashif B Naeem[SUP] 1 [/SUP], Mahmood Y Hachim, Ibrahim Y Hachim, Ayman Chkhis, Rajesh Quadros, Haifa Hannawi, Issa Al Salmi, Fahdah Alokaily, Suad Hannawi
Affiliations
Abstract
Objectives: To evaluate acute cardiac injury in COVID-19 patients and its association with adverse outcomes including mortality in the United Arab Emirates (UAE) population.
Methods: A retrospective study conducted between February and June 2020 in Dubai, UAE, for all laboratory-confirmed Coronavirus disease-19 patients. Demographic, clinical, laboratory, radiological, and clinical outcomes were compared between patients with and without acute cardiac injury.
Results: During the study period, 203 patients were included, of which, 44 (21.7%) had evidence of acute cardiac injury. Compared with patients without acute cardiac injury, patients with acute cardiac injury were: older, had more shortness of breath, diabetes, hypertension, and more bilateral airspace shadowing on admission chest radiography. These patients also had a higher neutrophil count, C-reactive protein, procalcitonin, ferritin, D-dimers and lactate dehydrogenase but lower lymphocyte count. Regarding outcomes, these patients had higher intensive care admissions; a higher rate of complications including acute kidney and liver injury, acidosis, septic shock, acute respiratory distress syndrome, needed more mechanical ventilation, and had a significantly higher risk of death.
Conclusion: Acute cardiac injury is common among Coronavirus disease-19 patients. These patients present with higher comorbidities, have high inflammatory markers and have greater risk for in-hospital multi-organ damage, need for mechanical ventilation, and death. Prompt full assessment and intervention are recommended.
. 2020 Nov;41(11):1204-1210.
doi: 10.15537/smj.2020.11.25466.
Acute cardiac injury is associated with adverse outcomes, including mortality in COVID-19 patients. A single-center experience
Kashif B Naeem[SUP] 1 [/SUP], Mahmood Y Hachim, Ibrahim Y Hachim, Ayman Chkhis, Rajesh Quadros, Haifa Hannawi, Issa Al Salmi, Fahdah Alokaily, Suad Hannawi
Affiliations
- PMID: 33130840
- DOI: 10.15537/smj.2020.11.25466
Abstract
Objectives: To evaluate acute cardiac injury in COVID-19 patients and its association with adverse outcomes including mortality in the United Arab Emirates (UAE) population.
Methods: A retrospective study conducted between February and June 2020 in Dubai, UAE, for all laboratory-confirmed Coronavirus disease-19 patients. Demographic, clinical, laboratory, radiological, and clinical outcomes were compared between patients with and without acute cardiac injury.
Results: During the study period, 203 patients were included, of which, 44 (21.7%) had evidence of acute cardiac injury. Compared with patients without acute cardiac injury, patients with acute cardiac injury were: older, had more shortness of breath, diabetes, hypertension, and more bilateral airspace shadowing on admission chest radiography. These patients also had a higher neutrophil count, C-reactive protein, procalcitonin, ferritin, D-dimers and lactate dehydrogenase but lower lymphocyte count. Regarding outcomes, these patients had higher intensive care admissions; a higher rate of complications including acute kidney and liver injury, acidosis, septic shock, acute respiratory distress syndrome, needed more mechanical ventilation, and had a significantly higher risk of death.
Conclusion: Acute cardiac injury is common among Coronavirus disease-19 patients. These patients present with higher comorbidities, have high inflammatory markers and have greater risk for in-hospital multi-organ damage, need for mechanical ventilation, and death. Prompt full assessment and intervention are recommended.